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• W2081498829 abstract "The effect of glycerol and desmopressin on exercise performance and hydration in triathletes. Med. Sci. Sports Exerc., Vol. 30, No. 8, pp. 1263-1269, 1998. Background: Hydration is an important determinant of athletic performance, and glycerol-containing solutions have been demonstrated to produce a state of hyperhydration. Secretion of arginine vasopressin (AVP) and/or other renal mechanisms may account for reduced urine output following glycerol ingestion. This study examined the effect of glycerol and the AVP analog desmopressin (DDAVP) on hydration and exercise performance in triathletes ingesting routine volumes of prerace fluids. Methods: Eight male triathletes ages 19 to 43 participated. After determination of their V˙O2peak, each athlete completed a strenuous exercise protocol three times involving 60 min of exercise at 70% V˙O2peak followed immediately by an incremental increase in workload every 2 min until exhaustion. Results: Pretreatment with 1 g·kg−1 glycerol or 20 μg of DDAVP intranasally failed to produce hyperhydration or any enhancement of athletic performance. There was a significant difference in reduction in body mass between DDAVP and control (P< 0.05) but no change in sweat volume. No physiologically relevant differences in plasma sodium, renin, or hemoglobin were seen with either active agent. Plasma osmolality did have a different time course in response to exercise following glycerol(P < 0.03) owing to a smaller incremental increase. Urine osmolality was also raised at baseline following glycerol (P < 0.05). Responses to exercise of plasma AVP, cortisol, and indices of carbohydrate metabolism were similar, although AVP was elevated following DDAVP administration (P< 0.01) owing to assay cross-reactivity. Conclusion: Although maintaining adequate hydration remains important for the endurance athlete, the routine use of either glycerol or DDAVP before athletic training or competition in a thermoneutral environment does not seem to confer any advantage over conventional fluid replacement." @default.
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• W2081498829 date "1998-08-01" @default.
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• W2081498829 title "The effect of glycerol and desmopressin on exercise performance and hydration in triathletes" @default.
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• W2081498829 doi "https://doi.org/10.1097/00005768-199808000-00013" @default.
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