Matches in SemOpenAlex for { <https://semopenalex.org/work/W2081558711> ?p ?o ?g. }
- W2081558711 endingPage "e1600" @default.
- W2081558711 startingPage "e1600" @default.
- W2081558711 abstract "Cell polarity is an essential feature of animal cells contributing to morphogenesis. During Xenopus gastrulation, it is known that chordamesoderm cells are polarized and intercalate each other allowing anterior-posterior elongation of the embryo proper by convergent extension (CE). Although it is well known that the cellular protrusions at both ends of polarized cells exert tractive force for intercalation and that PCP pathway is known to be essential for the cell polarity, little is known about what triggers the cell polarization and what the polarization causes to control intracellular events enabling the intercalation that leads to the CE. In our research, we used EB3 (end-binding 3), a member of +TIPs that bind to the plus end of microtubule (MT), to visualize the intracellular polarity of chordamesoderm cells during CE to investigate the trigger of the establishment of cell polarity. We found that EB3 movement is polarized in chordamesoderm cells and that the notochord-somite tissue boundary plays an essential role in generating the cell polarity. This polarity was generated before the change of cell morphology and the polarized movement of EB3 in chordamesoderm cells was also observed near the boundary between the chordamesoderm tissue and naïve ectoderm tissue or lateral mesoderm tissues induced by a low concentration of nodal mRNA. These suggest that definitive tissue separation established by the distinct levels of nodal signaling is essential for the chordamesodermal cells to acquire mediolateral cell polarity." @default.
- W2081558711 created "2016-06-24" @default.
- W2081558711 creator A5006909371 @default.
- W2081558711 creator A5027200315 @default.
- W2081558711 creator A5046526010 @default.
- W2081558711 date "2008-02-13" @default.
- W2081558711 modified "2023-09-25" @default.
- W2081558711 title "Coordination of Cell Polarity during Xenopus Gastrulation" @default.
- W2081558711 cites W154439523 @default.
- W2081558711 cites W1906875137 @default.
- W2081558711 cites W1964935836 @default.
- W2081558711 cites W1965871188 @default.
- W2081558711 cites W1971326877 @default.
- W2081558711 cites W1982115148 @default.
- W2081558711 cites W1990221937 @default.
- W2081558711 cites W1993199560 @default.
- W2081558711 cites W1996982933 @default.
- W2081558711 cites W1998109805 @default.
- W2081558711 cites W2000775801 @default.
- W2081558711 cites W2001496079 @default.
- W2081558711 cites W2002858128 @default.
- W2081558711 cites W2006671195 @default.
- W2081558711 cites W2020050544 @default.
- W2081558711 cites W2027894846 @default.
- W2081558711 cites W2030446659 @default.
- W2081558711 cites W2041702752 @default.
- W2081558711 cites W2047044219 @default.
- W2081558711 cites W2057939874 @default.
- W2081558711 cites W2070548790 @default.
- W2081558711 cites W2093521812 @default.
- W2081558711 cites W2105884976 @default.
- W2081558711 cites W2110198156 @default.
- W2081558711 cites W2112178369 @default.
- W2081558711 cites W2113144687 @default.
- W2081558711 cites W2114115521 @default.
- W2081558711 cites W2121055980 @default.
- W2081558711 cites W2122718601 @default.
- W2081558711 cites W2142888319 @default.
- W2081558711 cites W2165748821 @default.
- W2081558711 cites W2218934745 @default.
- W2081558711 doi "https://doi.org/10.1371/journal.pone.0001600" @default.
- W2081558711 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2223072" @default.
- W2081558711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18270587" @default.
- W2081558711 hasPublicationYear "2008" @default.
- W2081558711 type Work @default.
- W2081558711 sameAs 2081558711 @default.
- W2081558711 citedByCount "32" @default.
- W2081558711 countsByYear W20815587112012 @default.
- W2081558711 countsByYear W20815587112013 @default.
- W2081558711 countsByYear W20815587112014 @default.
- W2081558711 countsByYear W20815587112017 @default.
- W2081558711 countsByYear W20815587112018 @default.
- W2081558711 countsByYear W20815587112019 @default.
- W2081558711 countsByYear W20815587112020 @default.
- W2081558711 countsByYear W20815587112021 @default.
- W2081558711 countsByYear W20815587112022 @default.
- W2081558711 countsByYear W20815587112023 @default.
- W2081558711 crossrefType "journal-article" @default.
- W2081558711 hasAuthorship W2081558711A5006909371 @default.
- W2081558711 hasAuthorship W2081558711A5027200315 @default.
- W2081558711 hasAuthorship W2081558711A5046526010 @default.
- W2081558711 hasBestOaLocation W20815587111 @default.
- W2081558711 hasConcept C104317684 @default.
- W2081558711 hasConcept C129536746 @default.
- W2081558711 hasConcept C145103041 @default.
- W2081558711 hasConcept C1491633281 @default.
- W2081558711 hasConcept C185592680 @default.
- W2081558711 hasConcept C192586883 @default.
- W2081558711 hasConcept C196843134 @default.
- W2081558711 hasConcept C2776133846 @default.
- W2081558711 hasConcept C2777361361 @default.
- W2081558711 hasConcept C2779535977 @default.
- W2081558711 hasConcept C2780915607 @default.
- W2081558711 hasConcept C39587587 @default.
- W2081558711 hasConcept C49353375 @default.
- W2081558711 hasConcept C54355233 @default.
- W2081558711 hasConcept C79879829 @default.
- W2081558711 hasConcept C86803240 @default.
- W2081558711 hasConcept C87073359 @default.
- W2081558711 hasConcept C95444343 @default.
- W2081558711 hasConceptScore W2081558711C104317684 @default.
- W2081558711 hasConceptScore W2081558711C129536746 @default.
- W2081558711 hasConceptScore W2081558711C145103041 @default.
- W2081558711 hasConceptScore W2081558711C1491633281 @default.
- W2081558711 hasConceptScore W2081558711C185592680 @default.
- W2081558711 hasConceptScore W2081558711C192586883 @default.
- W2081558711 hasConceptScore W2081558711C196843134 @default.
- W2081558711 hasConceptScore W2081558711C2776133846 @default.
- W2081558711 hasConceptScore W2081558711C2777361361 @default.
- W2081558711 hasConceptScore W2081558711C2779535977 @default.
- W2081558711 hasConceptScore W2081558711C2780915607 @default.
- W2081558711 hasConceptScore W2081558711C39587587 @default.
- W2081558711 hasConceptScore W2081558711C49353375 @default.
- W2081558711 hasConceptScore W2081558711C54355233 @default.
- W2081558711 hasConceptScore W2081558711C79879829 @default.
- W2081558711 hasConceptScore W2081558711C86803240 @default.
- W2081558711 hasConceptScore W2081558711C87073359 @default.
- W2081558711 hasConceptScore W2081558711C95444343 @default.