Matches in SemOpenAlex for { <https://semopenalex.org/work/W2081567647> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2081567647 endingPage "227" @default.
- W2081567647 startingPage "217" @default.
- W2081567647 abstract "The lipophilic cation triphenylmethylphosphonium (TPMP+) and the potassium analog Rb+, were used to monitor the membrane potential (delta psi) of freshly isolated rabbit type II alveolar epithelial cells. Type II cells were found to accumulate TPMP+ rapidly at 37 degrees C in Hanks' balanced-salt solution with 5 microM tetraphenyl boron, but this accumulation was partially due to non-membrane potential dependent binding of TPMP+ to the cell. Lysophosphatidylcholine (lysoPC) was found to abolish delta psi and permitted correction for bound TPMP+ or Rb+. TPMP+ remaining in the cell following correction for binding represents the sum of mitochondrial and plasma membrane potential dependent accumulation. The accumulation of Rb+ by the type II cell was found to be independent of the mitochondrial membrane potential and indicated a trans-plasma membrane Rb+ distribution potential of -62.9 +/- 4 mV. A similar value was obtained by estimating the plasma membrane potential dependent accumulation of TPMP+ in type II cells whose mitochondria were depolarized with carbonylcyanide m-chlorophenylhydrazone (CCCP). The release of TPMP+ due to CCCP treatment also permitted an estimation for the trans-mitochondrial membrane potential of -141.8 +/- 10 mV. These techniques of membrane potential measurements were found to be sensitive to changes in delta psi induced by a number of inhibitors and ionophores. The ability to measure the membrane potential of the type II pneumocyte, and the changes caused by various agents, should be useful in characterizing the functional responses of this pulmonary surfactant producing cell." @default.
- W2081567647 created "2016-06-24" @default.
- W2081567647 creator A5015316695 @default.
- W2081567647 creator A5042304008 @default.
- W2081567647 creator A5089732429 @default.
- W2081567647 date "1984-04-01" @default.
- W2081567647 modified "2023-09-26" @default.
- W2081567647 title "Characterization of the plasma and mitochondrial membrane potentials of alveolar type II cells by the use of ionic probes" @default.
- W2081567647 cites W1533884306 @default.
- W2081567647 cites W1544605152 @default.
- W2081567647 cites W1757031429 @default.
- W2081567647 cites W1775749144 @default.
- W2081567647 cites W187935649 @default.
- W2081567647 cites W1975658051 @default.
- W2081567647 cites W1977779461 @default.
- W2081567647 cites W2000633160 @default.
- W2081567647 cites W2016809219 @default.
- W2081567647 cites W2019614324 @default.
- W2081567647 cites W2023489454 @default.
- W2081567647 cites W2025641397 @default.
- W2081567647 cites W2038475735 @default.
- W2081567647 cites W2092740788 @default.
- W2081567647 cites W2105979237 @default.
- W2081567647 cites W2123885139 @default.
- W2081567647 cites W2138483175 @default.
- W2081567647 cites W2159000703 @default.
- W2081567647 cites W2174107598 @default.
- W2081567647 cites W2281053656 @default.
- W2081567647 cites W2301287172 @default.
- W2081567647 doi "https://doi.org/10.1016/0005-2736(84)90536-4" @default.
- W2081567647 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6704396" @default.
- W2081567647 hasPublicationYear "1984" @default.
- W2081567647 type Work @default.
- W2081567647 sameAs 2081567647 @default.
- W2081567647 citedByCount "31" @default.
- W2081567647 countsByYear W20815676472013 @default.
- W2081567647 countsByYear W20815676472014 @default.
- W2081567647 countsByYear W20815676472018 @default.
- W2081567647 countsByYear W20815676472020 @default.
- W2081567647 countsByYear W20815676472021 @default.
- W2081567647 crossrefType "journal-article" @default.
- W2081567647 hasAuthorship W2081567647A5015316695 @default.
- W2081567647 hasAuthorship W2081567647A5042304008 @default.
- W2081567647 hasAuthorship W2081567647A5089732429 @default.
- W2081567647 hasConcept C12554922 @default.
- W2081567647 hasConcept C181911157 @default.
- W2081567647 hasConcept C185592680 @default.
- W2081567647 hasConcept C2776330855 @default.
- W2081567647 hasConcept C2778106830 @default.
- W2081567647 hasConcept C2778596009 @default.
- W2081567647 hasConcept C2778918659 @default.
- W2081567647 hasConcept C2780397019 @default.
- W2081567647 hasConcept C28859421 @default.
- W2081567647 hasConcept C41625074 @default.
- W2081567647 hasConcept C55493867 @default.
- W2081567647 hasConcept C58226133 @default.
- W2081567647 hasConcept C75385678 @default.
- W2081567647 hasConcept C86803240 @default.
- W2081567647 hasConceptScore W2081567647C12554922 @default.
- W2081567647 hasConceptScore W2081567647C181911157 @default.
- W2081567647 hasConceptScore W2081567647C185592680 @default.
- W2081567647 hasConceptScore W2081567647C2776330855 @default.
- W2081567647 hasConceptScore W2081567647C2778106830 @default.
- W2081567647 hasConceptScore W2081567647C2778596009 @default.
- W2081567647 hasConceptScore W2081567647C2778918659 @default.
- W2081567647 hasConceptScore W2081567647C2780397019 @default.
- W2081567647 hasConceptScore W2081567647C28859421 @default.
- W2081567647 hasConceptScore W2081567647C41625074 @default.
- W2081567647 hasConceptScore W2081567647C55493867 @default.
- W2081567647 hasConceptScore W2081567647C58226133 @default.
- W2081567647 hasConceptScore W2081567647C75385678 @default.
- W2081567647 hasConceptScore W2081567647C86803240 @default.
- W2081567647 hasIssue "2" @default.
- W2081567647 hasLocation W20815676471 @default.
- W2081567647 hasLocation W20815676472 @default.
- W2081567647 hasOpenAccess W2081567647 @default.
- W2081567647 hasPrimaryLocation W20815676471 @default.
- W2081567647 hasRelatedWork W2002081555 @default.
- W2081567647 hasRelatedWork W2015659974 @default.
- W2081567647 hasRelatedWork W2035370275 @default.
- W2081567647 hasRelatedWork W2064636876 @default.
- W2081567647 hasRelatedWork W2069885795 @default.
- W2081567647 hasRelatedWork W2081567647 @default.
- W2081567647 hasRelatedWork W2148200348 @default.
- W2081567647 hasRelatedWork W2153096281 @default.
- W2081567647 hasRelatedWork W3164241571 @default.
- W2081567647 hasRelatedWork W2480799483 @default.
- W2081567647 hasVolume "771" @default.
- W2081567647 isParatext "false" @default.
- W2081567647 isRetracted "false" @default.
- W2081567647 magId "2081567647" @default.
- W2081567647 workType "article" @default.