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- W2081569286 abstract "The recently identified endogenous agonists on the μ-opioid-receptor (μOR), endomorphin-1 (EM-1) and endomorphin-2 (EM-2), induce a concentration dependent inhibition of electrical field stimulation (EFS)-induced tachykinin-mediated contractions of the guinea-pig bronchus (ED50s <10 nM for both compounds). Surprisingly, only endomorphin-1 effects could be blocked by naloxone (10 μM), whereas endomorphin-2 effects were not affected by specific antagonists for the μ-, κ-, and δ-opioid-receptor. British Journal of Pharmacology (1999) 127, 605–608; doi:10.1038/sj.bjp.0702630" @default.
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- W2081569286 date "1999-06-01" @default.
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- W2081569286 title "Naloxone blocks endomorphin-1 but not endomorphin-2 induced inhibition of tachykinergic contractions of guinea-pig isolated bronchus" @default.
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- W2081569286 doi "https://doi.org/10.1038/sj.bjp.0702630" @default.
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