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- W2081608688 abstract "Phospholipid liposomes that contain Ca ions in inside compartment were subjected to external alternating electric fields of square wave form at several frequencies: 10, 100 Hz, 1, 10, 100 kHz. The leakage of Ca ions from inside to bulk solution caused by the electric fields was detected by the fluorescence change due to Ca-Quin 2 (fluorescent dye) complex formation in the bulk aqueous solution. The temperature increments of the sample solution in the chamber were also measured. The amplitude of the electric field and time interval between application of the electric field were varied. The frequency dependency of both the leakage of Ca ion and the temperature increments was observed. It was observed that the efficiency of the leakage had a minimum at 1 kHz. The origin of the frequency dependency of the leakage is discussed, and it is concluded that the energy consumption on a microscopic scale in the liposome membrane zone can be the reason for membrane permeation in this experimental system." @default.
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- W2081608688 date "2004-02-01" @default.
- W2081608688 modified "2023-10-18" @default.
- W2081608688 title "Ca ion permeation through liposome membranes with heat generation by square-wave electric field" @default.
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- W2081608688 doi "https://doi.org/10.1016/j.colsurfb.2003.10.011" @default.
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