Matches in SemOpenAlex for { <https://semopenalex.org/work/W2081684855> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2081684855 endingPage "102" @default.
- W2081684855 startingPage "97" @default.
- W2081684855 abstract "It is the conventional opinion that acquired aplastic anaemia is a heterogenous disease including basically different conditions, such as idiopathic or virus induced pancytopenia, toxic-allergic marrow damage or autoimmunity. Here, an alternative concept is proposed, according to which aplastic anaemia is one disease, but multifactorial in all patients, apparent differences being due to the relative prevalence of one or the other pathophysiological component in individual patients. Bone marrow from patients in the severe phase of aplastic anaemia does not grow in culture and is therefore not suitable for experimentation. Alternatively, bone marrow from patients who have resumed some degree of autologous bone marrow function, but still have residual signs of the disease after non-invasive therapy, offers the possibility to study pathophysiological mechanisms in vitro. The majority of experiments presented in this chapter have been done in such patients, assuming that their status of disease in some way reflects the original, more serious pretreatment condition. Three major pathophysiological components will be discussed, and it will be proposed how these factors act in concert to cause or aggravate aplasia." @default.
- W2081684855 created "2016-06-24" @default.
- W2081684855 creator A5031298294 @default.
- W2081684855 date "1990-06-01" @default.
- W2081684855 modified "2023-09-26" @default.
- W2081684855 title "Pathophysiology of aplastic anaemia" @default.
- W2081684855 cites W134881487 @default.
- W2081684855 cites W1981585780 @default.
- W2081684855 cites W1992316193 @default.
- W2081684855 cites W1993411007 @default.
- W2081684855 cites W2015241436 @default.
- W2081684855 cites W2029541173 @default.
- W2081684855 cites W2043697336 @default.
- W2081684855 cites W2045147585 @default.
- W2081684855 cites W2055023639 @default.
- W2081684855 cites W2055482423 @default.
- W2081684855 cites W2066665943 @default.
- W2081684855 cites W2072503775 @default.
- W2081684855 cites W2073914227 @default.
- W2081684855 cites W2075001955 @default.
- W2081684855 cites W2150673256 @default.
- W2081684855 cites W2165858236 @default.
- W2081684855 cites W2241219494 @default.
- W2081684855 cites W2262355130 @default.
- W2081684855 cites W2320441301 @default.
- W2081684855 cites W2334877708 @default.
- W2081684855 cites W2341215680 @default.
- W2081684855 cites W2345005943 @default.
- W2081684855 cites W2395446206 @default.
- W2081684855 cites W2397156964 @default.
- W2081684855 cites W2415034734 @default.
- W2081684855 cites W2426165764 @default.
- W2081684855 cites W2431850579 @default.
- W2081684855 cites W320992867 @default.
- W2081684855 cites W348012880 @default.
- W2081684855 doi "https://doi.org/10.1016/0268-960x(90)90032-n" @default.
- W2081684855 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2194600" @default.
- W2081684855 hasPublicationYear "1990" @default.
- W2081684855 type Work @default.
- W2081684855 sameAs 2081684855 @default.
- W2081684855 citedByCount "6" @default.
- W2081684855 countsByYear W20816848552018 @default.
- W2081684855 crossrefType "journal-article" @default.
- W2081684855 hasAuthorship W2081684855A5031298294 @default.
- W2081684855 hasConcept C10162356 @default.
- W2081684855 hasConcept C109159458 @default.
- W2081684855 hasConcept C126322002 @default.
- W2081684855 hasConcept C142724271 @default.
- W2081684855 hasConcept C203014093 @default.
- W2081684855 hasConcept C2778368355 @default.
- W2081684855 hasConcept C2779134260 @default.
- W2081684855 hasConcept C2779382419 @default.
- W2081684855 hasConcept C2780007613 @default.
- W2081684855 hasConcept C2780525284 @default.
- W2081684855 hasConcept C2781440808 @default.
- W2081684855 hasConcept C28328180 @default.
- W2081684855 hasConcept C2911114841 @default.
- W2081684855 hasConcept C54355233 @default.
- W2081684855 hasConcept C71924100 @default.
- W2081684855 hasConcept C86803240 @default.
- W2081684855 hasConceptScore W2081684855C10162356 @default.
- W2081684855 hasConceptScore W2081684855C109159458 @default.
- W2081684855 hasConceptScore W2081684855C126322002 @default.
- W2081684855 hasConceptScore W2081684855C142724271 @default.
- W2081684855 hasConceptScore W2081684855C203014093 @default.
- W2081684855 hasConceptScore W2081684855C2778368355 @default.
- W2081684855 hasConceptScore W2081684855C2779134260 @default.
- W2081684855 hasConceptScore W2081684855C2779382419 @default.
- W2081684855 hasConceptScore W2081684855C2780007613 @default.
- W2081684855 hasConceptScore W2081684855C2780525284 @default.
- W2081684855 hasConceptScore W2081684855C2781440808 @default.
- W2081684855 hasConceptScore W2081684855C28328180 @default.
- W2081684855 hasConceptScore W2081684855C2911114841 @default.
- W2081684855 hasConceptScore W2081684855C54355233 @default.
- W2081684855 hasConceptScore W2081684855C71924100 @default.
- W2081684855 hasConceptScore W2081684855C86803240 @default.
- W2081684855 hasIssue "2" @default.
- W2081684855 hasLocation W20816848551 @default.
- W2081684855 hasLocation W20816848552 @default.
- W2081684855 hasOpenAccess W2081684855 @default.
- W2081684855 hasPrimaryLocation W20816848551 @default.
- W2081684855 hasRelatedWork W1598447182 @default.
- W2081684855 hasRelatedWork W1982381511 @default.
- W2081684855 hasRelatedWork W2024787846 @default.
- W2081684855 hasRelatedWork W2067127020 @default.
- W2081684855 hasRelatedWork W2081684855 @default.
- W2081684855 hasRelatedWork W2125837235 @default.
- W2081684855 hasRelatedWork W224593611 @default.
- W2081684855 hasRelatedWork W2412260717 @default.
- W2081684855 hasRelatedWork W25463327 @default.
- W2081684855 hasRelatedWork W3210399675 @default.
- W2081684855 hasVolume "4" @default.
- W2081684855 isParatext "false" @default.
- W2081684855 isRetracted "false" @default.
- W2081684855 magId "2081684855" @default.
- W2081684855 workType "article" @default.