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- W2081708097 abstract "A large majority of allogeneic hematopoietic stem cell donations are achieved using granulocyte-colony stimulating factor (G-CSF). G-CSF use has been associated with later development of myelodysplastic syndromes/acute myelogenous leukemia (MDS/AML) in several clinical circumstances. Although clinical data to date have failed to identify any increased incidence of MDS/AML in G-CSF mobilized donors, the quality of these data are insufficient to exclude a long-term risk. Physicians should explain the potential risk to donors, and where appropriate, offer donors the option of marrow donation. A large majority of allogeneic hematopoietic stem cell donations are achieved using granulocyte-colony stimulating factor (G-CSF). G-CSF use has been associated with later development of myelodysplastic syndromes/acute myelogenous leukemia (MDS/AML) in several clinical circumstances. Although clinical data to date have failed to identify any increased incidence of MDS/AML in G-CSF mobilized donors, the quality of these data are insufficient to exclude a long-term risk. Physicians should explain the potential risk to donors, and where appropriate, offer donors the option of marrow donation." @default.
- W2081708097 created "2016-06-24" @default.
- W2081708097 creator A5009719497 @default.
- W2081708097 creator A5018065917 @default.
- W2081708097 creator A5069014112 @default.
- W2081708097 date "2011-12-01" @default.
- W2081708097 modified "2023-10-16" @default.
- W2081708097 title "Can G-CSF Cause Leukemia in Hematopoietic Stem Cell Donors?" @default.
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- W2081708097 doi "https://doi.org/10.1016/j.bbmt.2011.07.003" @default.
- W2081708097 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21745453" @default.
- W2081708097 hasPublicationYear "2011" @default.
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