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- W2081717721 abstract "Integral β-barrel proteins are found in the outer membranes of mitochondria, chloroplasts, and Gram-negative bacteria. The machine that assembles these proteins contains an integral membrane protein, called YaeT in Escherichia coli , which has one or more polypeptide transport–associated (POTRA) domains. The crystal structure of a periplasmic fragment of YaeT reveals the POTRA domain fold and suggests a model for how POTRA domains can bind different peptide sequences, as required for a machine that handles numerous β-barrel protein precursors. Analysis of POTRA domain deletions shows which are essential and provides a view of the spatial organization of this assembly machine." @default.
- W2081717721 created "2016-06-24" @default.
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- W2081717721 date "2007-08-17" @default.
- W2081717721 modified "2023-10-03" @default.
- W2081717721 title "Structure and Function of an Essential Component of the Outer Membrane Protein Assembly Machine" @default.
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- W2081717721 doi "https://doi.org/10.1126/science.1143993" @default.
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