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- W2081730149 abstract "Radioimmunoimaging characteristics of a new monoclonal antibody EBA-1 and its F(ab′)2 fragments utilizing nu/nu mice bearing human breast carcinoma xenografts are described. 111In-DTPA conjugates of EBA-1 localized with tumor/blood ratios of 0.99 ± 0.10 (P < 0.3) and 4.65 ± 1.60 (P < 0.05), and localization indices of 1.25 and 2.61 at 24 and 72 h, respectively. A tumor/blood ratio as high as 28.86 ± 6.90 (P < 0.025) was obtained with EBA-1 F(ab′)2 radioconjugates at 48 h. These results suggest that EBA-1 and its F(ab′)2 might be useful reagents in radioimmunoimaging and radioimmunotherapy." @default.
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- W2081730149 date "1993-04-01" @default.
- W2081730149 modified "2023-09-23" @default.
- W2081730149 title "Radioimmunoimaging of human breast carcinoma xenografts in nude mouse model with 111In-labeled new monoclonal antibody EBA-1 and F(ab′)2 fragments" @default.
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- W2081730149 doi "https://doi.org/10.1016/0969-8051(93)90055-y" @default.
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