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- W2081737441 abstract "Fetal infection with toxoplasmosis can cause large damage to central nervous system. In France, maternal systematic serological screening during pregnancy allows early diagnosis of fetal infection relying on amniocentesis with PCR analysis of the amniotic fluid and mice inoculation. When a fetus is known to be infected after the first trimester, according to the age of gestation and to the initial aspect of ultrasound survey, a specific treatment can be started. including pyrimethamine and sulfadiazine. Ultrasound survey is then performed every fortnight. When an Ultrasound anomaly is detected, fetal IRM can be performed. It will not detect the hyperechogenicities but can show tissular modifications such as polymicrogyrie. We report various aspects of ultrasound survey including brain lesions as rapidly progressive ventricular dilatations, parenchymal abces, hyperechogenicities, sub ependymal cysts. Ultrasonographic images are compared to pathological aspects. When the pregnancy goes on, these brain lesions can, to some extend, respond to specific treatment, although severe anomalies never disappear leading to a compromised development." @default.
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- W2081737441 date "2003-01-01" @default.
- W2081737441 modified "2023-09-23" @default.
- W2081737441 title "P338: Fetal toxoplasmosis infection. Brain ultrasound anomalies. An update." @default.
- W2081737441 doi "https://doi.org/10.1002/uog.807" @default.
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