FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2081768879> ?p ?o ?g. }

• W2081768879 endingPage "367" @default.
• W2081768879 startingPage "361" @default.
• W2081768879 abstract "We have determined that developing schistosomulae and adults of Schistosoma mansoni synthesize a wide range of eicosanoids when stimulated with linoleic acid, an essential fatty acid. Developing schistosomulae secrete 64%, while adults secrete over 80% of synthesized eicosanoids. On a per milligram soluble protein basis, eicosanoid secretion is ordered as follows: adult females greater than adult males much much greater than developing schistosomulae. Together one mature adult worm pair secreted approximately 4.36 micrograms prostaglandin E, 3.41 micrograms leukotriene B4, and 15.13 micrograms 5-hydroxyeicosatetraenoic acid (HETE) as determined by radioimmunoassay (RIA). High-performance liquid chromatography (HPLC) results have determined that 15-HETE is the major HETE species secreted by adults and developing schistosomulae. The immunosuppressant roles of 15-HETE, PGE, and LTB4 are discussed in relation to a possible mechanism for S. mansoni to evade the host immune system. Adults and schistosomules of S. mansoni have evolved rather sophisticated mechanisms for evading the host immune response. These include both host antigen acquisition and antigen shedding. In addition, young schistosomes have an as yet unidentified intrinsic defense mechanism against the host immune system. We postulate that part of the defense mechanism in schistosomules and adults may involve secretion of immunosuppressant eicosanoid species." @default.
• W2081768879 created "2016-06-24" @default.
• W2081768879 creator A5066960751 @default.
• W2081768879 creator A5090559101 @default.
• W2081768879 date "1987-12-01" @default.
• W2081768879 modified "2023-10-16" @default.
• W2081768879 title "Schistosoma mansoni: A comparison of secreted vs nonsecreted eicosanoids in developing schistosomulae and adults" @default.
• W2081768879 cites W1977156872 @default.
• W2081768879 cites W1984471731 @default.
• W2081768879 cites W1987730353 @default.
• W2081768879 cites W1995847463 @default.
• W2081768879 cites W2005566381 @default.
• W2081768879 cites W2034615402 @default.
• W2081768879 cites W2041270931 @default.
• W2081768879 cites W2047031361 @default.
• W2081768879 cites W2059335071 @default.
• W2081768879 cites W2065990680 @default.
• W2081768879 cites W2072994164 @default.
• W2081768879 cites W2085265412 @default.
• W2081768879 cites W2092971835 @default.
• W2081768879 cites W2104871682 @default.
• W2081768879 cites W2105021217 @default.
• W2081768879 cites W2186924601 @default.
• W2081768879 cites W2315549694 @default.
• W2081768879 cites W2319622331 @default.
• W2081768879 cites W2328031273 @default.
• W2081768879 cites W2408866453 @default.
• W2081768879 cites W4300697074 @default.
• W2081768879 cites W982380865 @default.
• W2081768879 doi "https://doi.org/10.1016/0014-4894(87)90048-8" @default.
• W2081768879 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2824233" @default.
• W2081768879 hasPublicationYear "1987" @default.
• W2081768879 type Work @default.
• W2081768879 sameAs 2081768879 @default.
• W2081768879 citedByCount "41" @default.
• W2081768879 countsByYear W20817688792012 @default.
• W2081768879 countsByYear W20817688792013 @default.
• W2081768879 countsByYear W20817688792014 @default.
• W2081768879 countsByYear W20817688792015 @default.
• W2081768879 countsByYear W20817688792016 @default.
• W2081768879 countsByYear W20817688792018 @default.
• W2081768879 countsByYear W20817688792019 @default.
• W2081768879 countsByYear W20817688792021 @default.
• W2081768879 crossrefType "journal-article" @default.
• W2081768879 hasAuthorship W2081768879A5066960751 @default.
• W2081768879 hasAuthorship W2081768879A5090559101 @default.
• W2081768879 hasConcept C126322002 @default.
• W2081768879 hasConcept C134018914 @default.
• W2081768879 hasConcept C147483822 @default.
• W2081768879 hasConcept C165901193 @default.
• W2081768879 hasConcept C176685330 @default.
• W2081768879 hasConcept C181199279 @default.
• W2081768879 hasConcept C203014093 @default.
• W2081768879 hasConcept C2776042228 @default.
• W2081768879 hasConcept C2776225656 @default.
• W2081768879 hasConcept C2776352991 @default.
• W2081768879 hasConcept C2776452501 @default.
• W2081768879 hasConcept C2776685179 @default.
• W2081768879 hasConcept C2776863245 @default.
• W2081768879 hasConcept C2776914184 @default.
• W2081768879 hasConcept C2778078955 @default.
• W2081768879 hasConcept C2780664492 @default.
• W2081768879 hasConcept C49039625 @default.
• W2081768879 hasConcept C55493867 @default.
• W2081768879 hasConcept C71924100 @default.
• W2081768879 hasConcept C86803240 @default.
• W2081768879 hasConcept C8891405 @default.
• W2081768879 hasConceptScore W2081768879C126322002 @default.
• W2081768879 hasConceptScore W2081768879C134018914 @default.
• W2081768879 hasConceptScore W2081768879C147483822 @default.
• W2081768879 hasConceptScore W2081768879C165901193 @default.
• W2081768879 hasConceptScore W2081768879C176685330 @default.
• W2081768879 hasConceptScore W2081768879C181199279 @default.
• W2081768879 hasConceptScore W2081768879C203014093 @default.
• W2081768879 hasConceptScore W2081768879C2776042228 @default.
• W2081768879 hasConceptScore W2081768879C2776225656 @default.
• W2081768879 hasConceptScore W2081768879C2776352991 @default.
• W2081768879 hasConceptScore W2081768879C2776452501 @default.
• W2081768879 hasConceptScore W2081768879C2776685179 @default.
• W2081768879 hasConceptScore W2081768879C2776863245 @default.
• W2081768879 hasConceptScore W2081768879C2776914184 @default.
• W2081768879 hasConceptScore W2081768879C2778078955 @default.
• W2081768879 hasConceptScore W2081768879C2780664492 @default.
• W2081768879 hasConceptScore W2081768879C49039625 @default.
• W2081768879 hasConceptScore W2081768879C55493867 @default.
• W2081768879 hasConceptScore W2081768879C71924100 @default.
• W2081768879 hasConceptScore W2081768879C86803240 @default.
• W2081768879 hasConceptScore W2081768879C8891405 @default.
• W2081768879 hasIssue "3" @default.
• W2081768879 hasLocation W20817688791 @default.
• W2081768879 hasLocation W20817688792 @default.
• W2081768879 hasOpenAccess W2081768879 @default.
• W2081768879 hasPrimaryLocation W20817688791 @default.
• W2081768879 hasRelatedWork W1992865522 @default.
• W2081768879 hasRelatedWork W2038796486 @default.
• W2081768879 hasRelatedWork W2053306032 @default.
• W2081768879 hasRelatedWork W2076094967 @default.
• W2081768879 hasRelatedWork W2106821047 @default.

• next