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• W2081787426 abstract "Lymphocystis disease virus (LCDV), a virus of Iridoviridae, can infect numerous teleost species, causing serious losses of aquaculture industry, and thus effective ways of prophylaxis and treatment are demanded. Previous studies have shown that phosvitin (Pv) is an antimicrobial agent in zebrafish, and vitellogenin, the precursor of yolk proteins including Pv, is able to neutralize virus, we thus hypothesize that Pv may have an antiviral activity. Here we clearly demonstrated that recombinant Pv (rPv) purified was capable of inhibiting the cytopathic effect in LCDV-infected cells and reducing the virus quantities in the infected cells as well as in the infected zebrafish. These data indicate that Pv possesses an antiviral activity and participates in immune defense of host against the infection by viruses like LCDV." @default.
• W2081787426 created "2016-06-24" @default.
• W2081787426 creator A5033919240 @default.
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• W2081787426 date "2013-05-01" @default.
• W2081787426 modified "2023-09-25" @default.
• W2081787426 title "Antiviral activity of phosvitin from zebrafish Danio rerio" @default.
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• W2081787426 doi "https://doi.org/10.1016/j.dci.2012.12.009" @default.
• W2081787426 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23305746" @default.
• W2081787426 hasPublicationYear "2013" @default.
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