Matches in SemOpenAlex for { <https://semopenalex.org/work/W2081879843> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2081879843 endingPage "249" @default.
- W2081879843 startingPage "244" @default.
- W2081879843 abstract "Regional lymph node status is an important predictor of survival in patients with malignant melanoma. Mapping of sentinel lymph nodes using sensitive molecular techniques has recently been introduced. Malignant melanoma is heterogeneous in terms of its biological, immunological and metastatic properties, and melanoma cells exhibit a polymorphous expression of tumour markers. Thus, assays that include multiple markers appear to be more sensitive than single-marker assays.To characterize the molecular profiles of melanoma cells in sentinel lymph nodes employing the mRNA expression of tyrosinase, MIA and MART-1 as markers.Samples of sentinel lymph nodes from 17 melanoma patients and 18 control nodes from non-melanoma patients were assayed by reverse transcriptase-polymerase chain reaction, using specific primers for each marker.We found that both tyrosinase and MIA expression were sensitive indicators of micrometastases in sentinel lymph nodes that were negative on routine histopathological examination, and that the finding of micrometastases expressing MART-1 in sentinel lymph nodes was negatively correlated with overall survival.Characterization of the molecular profiles of melanoma cells constitutes a valid means of detecting metastatic melanoma cells in sentinel lymph nodes, and of predicting the survival of melanoma patients." @default.
- W2081879843 created "2016-06-24" @default.
- W2081879843 creator A5005611842 @default.
- W2081879843 creator A5007942645 @default.
- W2081879843 creator A5074296844 @default.
- W2081879843 creator A5080436588 @default.
- W2081879843 creator A5084095256 @default.
- W2081879843 date "2002-02-01" @default.
- W2081879843 modified "2023-10-16" @default.
- W2081879843 title "Expression of tyrosinase, MIA and MART-1 in sentinel lymph nodes of patients with malignant melanoma" @default.
- W2081879843 cites W1901112984 @default.
- W2081879843 cites W1926637130 @default.
- W2081879843 cites W1953419682 @default.
- W2081879843 cites W1968122151 @default.
- W2081879843 cites W1982593033 @default.
- W2081879843 cites W1990458632 @default.
- W2081879843 cites W1993234572 @default.
- W2081879843 cites W1996568527 @default.
- W2081879843 cites W2016438927 @default.
- W2081879843 cites W2022171676 @default.
- W2081879843 cites W2051590190 @default.
- W2081879843 cites W2071034864 @default.
- W2081879843 cites W2112858728 @default.
- W2081879843 cites W2134000357 @default.
- W2081879843 cites W2142647027 @default.
- W2081879843 cites W2143422545 @default.
- W2081879843 cites W2146600597 @default.
- W2081879843 cites W2172203250 @default.
- W2081879843 cites W2225834302 @default.
- W2081879843 cites W2321256948 @default.
- W2081879843 cites W2400744200 @default.
- W2081879843 cites W37316445 @default.
- W2081879843 cites W4242546443 @default.
- W2081879843 cites W4250357349 @default.
- W2081879843 doi "https://doi.org/10.1046/j.1365-2133.2002.04579.x" @default.
- W2081879843 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11903234" @default.
- W2081879843 hasPublicationYear "2002" @default.
- W2081879843 type Work @default.
- W2081879843 sameAs 2081879843 @default.
- W2081879843 citedByCount "32" @default.
- W2081879843 countsByYear W20818798432014 @default.
- W2081879843 countsByYear W20818798432017 @default.
- W2081879843 countsByYear W20818798432019 @default.
- W2081879843 crossrefType "journal-article" @default.
- W2081879843 hasAuthorship W2081879843A5005611842 @default.
- W2081879843 hasAuthorship W2081879843A5007942645 @default.
- W2081879843 hasAuthorship W2081879843A5074296844 @default.
- W2081879843 hasAuthorship W2081879843A5080436588 @default.
- W2081879843 hasAuthorship W2081879843A5084095256 @default.
- W2081879843 hasConcept C121608353 @default.
- W2081879843 hasConcept C126322002 @default.
- W2081879843 hasConcept C142724271 @default.
- W2081879843 hasConcept C2777658100 @default.
- W2081879843 hasConcept C2778123414 @default.
- W2081879843 hasConcept C2779013556 @default.
- W2081879843 hasConcept C2779720271 @default.
- W2081879843 hasConcept C2780212769 @default.
- W2081879843 hasConcept C2780849966 @default.
- W2081879843 hasConcept C502942594 @default.
- W2081879843 hasConcept C530470458 @default.
- W2081879843 hasConcept C71924100 @default.
- W2081879843 hasConceptScore W2081879843C121608353 @default.
- W2081879843 hasConceptScore W2081879843C126322002 @default.
- W2081879843 hasConceptScore W2081879843C142724271 @default.
- W2081879843 hasConceptScore W2081879843C2777658100 @default.
- W2081879843 hasConceptScore W2081879843C2778123414 @default.
- W2081879843 hasConceptScore W2081879843C2779013556 @default.
- W2081879843 hasConceptScore W2081879843C2779720271 @default.
- W2081879843 hasConceptScore W2081879843C2780212769 @default.
- W2081879843 hasConceptScore W2081879843C2780849966 @default.
- W2081879843 hasConceptScore W2081879843C502942594 @default.
- W2081879843 hasConceptScore W2081879843C530470458 @default.
- W2081879843 hasConceptScore W2081879843C71924100 @default.
- W2081879843 hasIssue "2" @default.
- W2081879843 hasLocation W20818798431 @default.
- W2081879843 hasLocation W20818798432 @default.
- W2081879843 hasOpenAccess W2081879843 @default.
- W2081879843 hasPrimaryLocation W20818798431 @default.
- W2081879843 hasRelatedWork W1975337694 @default.
- W2081879843 hasRelatedWork W198962690 @default.
- W2081879843 hasRelatedWork W1996568527 @default.
- W2081879843 hasRelatedWork W2079678431 @default.
- W2081879843 hasRelatedWork W2090463034 @default.
- W2081879843 hasRelatedWork W2107729139 @default.
- W2081879843 hasRelatedWork W2118262515 @default.
- W2081879843 hasRelatedWork W2357888066 @default.
- W2081879843 hasRelatedWork W2387549903 @default.
- W2081879843 hasRelatedWork W2409969332 @default.
- W2081879843 hasVolume "146" @default.
- W2081879843 isParatext "false" @default.
- W2081879843 isRetracted "false" @default.
- W2081879843 magId "2081879843" @default.
- W2081879843 workType "article" @default.