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- W208199419 abstract "Objective To analyze the clinicopathological characteristics and prognosis of primary intestinal lymphoma. Methods The clinical and pathological data of 121 cases of primary intestinal lymphoma were reviewed.The pathology was examined by HE and immunohistochemical staining and reclassified according to the 2008 WHO classification of tumors derived from haematopoietic and lymphoid tissues.The clinical data were analyzed by Kaplan-Meier method. Results The age of patients ranged from 7 to 81 years,with an average of 52.7 years and median of 55 years.The male-to-female ratio was 8∶3(88∶33).The most frequent site of the lesions was the large intestine (n=62,51.2%),followed by small intestine (n=47,38.8%),duodenum (n=7,5.8%),multiple intestinal sites (n=4,3.3%) and appendix (n=1,0.8%).The clinical presentations included abdominal pain and/or distention (72.9%); lower digestive tract hemorrhage (22.0%),fever (10.2%),abdominal mass (8.5%),diarrhea (8.5%) and weight loss (5.1%).The major gross findings were bossing (37.3%),ulcer (33.9%) and infiltrating (28.8%).The diagnoses were:not specified diffuse large B-cell lymphoma (68/121,56.2% ),MALT lymphoma (18/121,14.9%),not specified peripheral T-cell lymphoma (13/121,10.7%),enteropathy-associated T-cell lymphoma(7/121,5.8%),extranodal NK/T cell lymphoma,nasal-type(4/121,3.3%),mantle cell lymphoma (3/121,2.5%),follicular lymphoma (3/121,2.5%),anaplastic large cell lymphoma,ALK-negative (2/121,1.7%),chronic lymphocytic leukemia /small lymphocytic lymphoma (1/121,0.8%),Burkitt lymphoma (1/121,0.8%) and unclassifiable B-cell lymphoma (1/121,0.8%).The follow-up time of 39 cases was 1~102 month with an average of 19.7 months.Conclusions Primary intestinal lymphoma can usually be found in mid-aged and elderly males.Large intestine (colon,rectum) is the most common site involved.Abdominal pain and/or distention are the common clinical manifestations.Diffuse large B-cell lymphoma,not otherwise specified is the most common histological type.Compared with B-cell lymphoma,primary intestinal T-cell lymphoma has a worse prognosis." @default.
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- W208199419 date "2009-01-01" @default.
- W208199419 modified "2023-09-24" @default.
- W208199419 title "Clinicopathological analysis of primary intestinal lymphoma: a report of 121 cases." @default.
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