Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082004906> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2082004906 endingPage "315" @default.
- W2082004906 startingPage "310" @default.
- W2082004906 abstract "The nitrocompounds 3-nitropropanol (NPOH) and 3-nitropropionic acid (NPA) were shown to be equally toxic when injected intraperitoneally into male Wistar rats. The LD50 for NPOH was 0.58 mmol/kg and for NPA it was 0.56 mmol/kg. NPOH was rapidly metabolized to NPA but this conversion was suppressed by prior administration of ethanol or 4-methylpyrazole to inhibit alcohol dehydrogenase. Administration of ethanol or 4-methylpyrazole before NPOH protected rats from intoxication. However, if the alcohol dehydrogenase inhibitors were given after the nitroalcohol, toxicity still occurred. Administration of the aldehyde dehydrogenase inhibitor diethyldithiocarbamic acid had little effect on the conversion of NPOH to NPA and did not alter the toxicity of NPOH. It was concluded that NPOH and NPA are equally toxic to rats but that NPOH is toxic due to its being rapidly converted to NPA." @default.
- W2082004906 created "2016-06-24" @default.
- W2082004906 creator A5027923205 @default.
- W2082004906 creator A5039286247 @default.
- W2082004906 creator A5056236598 @default.
- W2082004906 creator A5066694016 @default.
- W2082004906 date "1985-04-01" @default.
- W2082004906 modified "2023-10-12" @default.
- W2082004906 title "Effect of alcohol and aldehyde dehydrogenase inhibitors on the toxicity of 3-nitropropanol in rats" @default.
- W2082004906 cites W125738678 @default.
- W2082004906 cites W143108331 @default.
- W2082004906 cites W1607363102 @default.
- W2082004906 cites W1966568966 @default.
- W2082004906 cites W1972296376 @default.
- W2082004906 cites W1980284387 @default.
- W2082004906 cites W1987710703 @default.
- W2082004906 cites W1987812153 @default.
- W2082004906 cites W1987855345 @default.
- W2082004906 cites W1989708168 @default.
- W2082004906 cites W2015259400 @default.
- W2082004906 cites W2023758851 @default.
- W2082004906 cites W2055414594 @default.
- W2082004906 cites W2065148915 @default.
- W2082004906 cites W2089444449 @default.
- W2082004906 cites W2227741897 @default.
- W2082004906 cites W2267400930 @default.
- W2082004906 cites W2341495118 @default.
- W2082004906 cites W2439725228 @default.
- W2082004906 cites W2563405676 @default.
- W2082004906 doi "https://doi.org/10.1016/0041-008x(85)90294-7" @default.
- W2082004906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2994256" @default.
- W2082004906 hasPublicationYear "1985" @default.
- W2082004906 type Work @default.
- W2082004906 sameAs 2082004906 @default.
- W2082004906 citedByCount "27" @default.
- W2082004906 countsByYear W20820049062012 @default.
- W2082004906 countsByYear W20820049062013 @default.
- W2082004906 countsByYear W20820049062015 @default.
- W2082004906 countsByYear W20820049062018 @default.
- W2082004906 countsByYear W20820049062021 @default.
- W2082004906 crossrefType "journal-article" @default.
- W2082004906 hasAuthorship W2082004906A5027923205 @default.
- W2082004906 hasAuthorship W2082004906A5039286247 @default.
- W2082004906 hasAuthorship W2082004906A5056236598 @default.
- W2082004906 hasAuthorship W2082004906A5066694016 @default.
- W2082004906 hasConcept C167552308 @default.
- W2082004906 hasConcept C178790620 @default.
- W2082004906 hasConcept C181199279 @default.
- W2082004906 hasConcept C185592680 @default.
- W2082004906 hasConcept C25747580 @default.
- W2082004906 hasConcept C2777344606 @default.
- W2082004906 hasConcept C2780161600 @default.
- W2082004906 hasConcept C2781066024 @default.
- W2082004906 hasConcept C29730261 @default.
- W2082004906 hasConcept C55493867 @default.
- W2082004906 hasConcept C71924100 @default.
- W2082004906 hasConcept C98274493 @default.
- W2082004906 hasConceptScore W2082004906C167552308 @default.
- W2082004906 hasConceptScore W2082004906C178790620 @default.
- W2082004906 hasConceptScore W2082004906C181199279 @default.
- W2082004906 hasConceptScore W2082004906C185592680 @default.
- W2082004906 hasConceptScore W2082004906C25747580 @default.
- W2082004906 hasConceptScore W2082004906C2777344606 @default.
- W2082004906 hasConceptScore W2082004906C2780161600 @default.
- W2082004906 hasConceptScore W2082004906C2781066024 @default.
- W2082004906 hasConceptScore W2082004906C29730261 @default.
- W2082004906 hasConceptScore W2082004906C55493867 @default.
- W2082004906 hasConceptScore W2082004906C71924100 @default.
- W2082004906 hasConceptScore W2082004906C98274493 @default.
- W2082004906 hasIssue "2" @default.
- W2082004906 hasLocation W20820049061 @default.
- W2082004906 hasLocation W20820049062 @default.
- W2082004906 hasOpenAccess W2082004906 @default.
- W2082004906 hasPrimaryLocation W20820049061 @default.
- W2082004906 hasRelatedWork W128901179 @default.
- W2082004906 hasRelatedWork W1992119000 @default.
- W2082004906 hasRelatedWork W2019176894 @default.
- W2082004906 hasRelatedWork W2066175921 @default.
- W2082004906 hasRelatedWork W2074052481 @default.
- W2082004906 hasRelatedWork W2134978753 @default.
- W2082004906 hasRelatedWork W2144214926 @default.
- W2082004906 hasRelatedWork W2180134276 @default.
- W2082004906 hasRelatedWork W2467119538 @default.
- W2082004906 hasRelatedWork W2295232143 @default.
- W2082004906 hasVolume "78" @default.
- W2082004906 isParatext "false" @default.
- W2082004906 isRetracted "false" @default.
- W2082004906 magId "2082004906" @default.
- W2082004906 workType "article" @default.