FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082012028> ?p ?o ?g. }

• W2082012028 endingPage "1257" @default.
• W2082012028 startingPage "1248" @default.
• W2082012028 abstract "<h3>BACKGROUND:</h3> Ventilator management for children with hypoxemic respiratory failure may benefit from ventilator protocols, which rely on blood gases. Accurate noninvasive estimates for pH or P_aCO₂ could allow frequent ventilator changes to optimize lung-protective ventilation strategies. If these models are highly accurate, they can facilitate the development of closed-loop ventilator systems. We sought to develop and test algorithms for estimating pH and P_aCO₂ from measures of ventilator support, pulse oximetry, and end-tidal carbon dioxide pressure (P_ETCO₂). We also sought to determine whether surrogates for changes in dead space can improve prediction. <h3>METHODS:</h3> Algorithms were developed and tested using 2 data sets from previously published investigations. A baseline model estimated pH and P_aCO₂ from P_ETCO₂ using the previously observed relationship between P_ETCO₂ and P_aCO₂ or pH (using the Henderson-Hasselbalch equation). We developed a multivariate gaussian process (MGP) model incorporating other available noninvasive measurements. <h3>RESULTS:</h3> The training data set had 2,386 observations from 274 children, and the testing data set had 658 observations from 83 children. The baseline model predicted P_aCO₂ within ± 7 mm Hg of the observed P_aCO₂ 80% of the time. The MGP model improved this to ± 6 mm Hg. When the MGP model predicted P_aCO₂ between 35 and 60 mm Hg, the 80% prediction interval narrowed to ± 5 mm Hg. The baseline model predicted pH within ± 0.07 of the observed pH 80% of the time. The MGP model improved this to ± 0.05. <h3>CONCLUSIONS:</h3> We have demonstrated a conceptual first step for predictive models that estimate pH and P_aCO₂ to facilitate clinical decision making for children with lung injury. These models may have some applicability when incorporated in ventilator protocols to encourage practitioners to maintain permissive hypercapnia when using high ventilator support. Refinement with additional data may improve model accuracy." @default.
• W2082012028 created "2016-06-24" @default.
• W2082012028 creator A5006055654 @default.
• W2082012028 creator A5037209289 @default.
• W2082012028 creator A5040729990 @default.
• W2082012028 creator A5075768180 @default.
• W2082012028 creator A5085020072 @default.
• W2082012028 creator A5086572473 @default.
• W2082012028 creator A5091230938 @default.
• W2082012028 date "2013-12-24" @default.
• W2082012028 modified "2023-10-07" @default.
• W2082012028 title "Algorithms to Estimate P_aCO₂and pH Using Noninvasive Parameters for Children with Hypoxemic Respiratory Failure" @default.
• W2082012028 cites W12150989 @default.
• W2082012028 cites W1526478472 @default.
• W2082012028 cites W1543675445 @default.
• W2082012028 cites W1967710271 @default.
• W2082012028 cites W1983638123 @default.
• W2082012028 cites W1990135479 @default.
• W2082012028 cites W2007176121 @default.
• W2082012028 cites W2014765477 @default.
• W2082012028 cites W2014803145 @default.
• W2082012028 cites W2016890843 @default.
• W2082012028 cites W2017651161 @default.
• W2082012028 cites W2026172047 @default.
• W2082012028 cites W2029661393 @default.
• W2082012028 cites W2030400109 @default.
• W2082012028 cites W2065141787 @default.
• W2082012028 cites W2071901407 @default.
• W2082012028 cites W2073299367 @default.
• W2082012028 cites W2100802962 @default.
• W2082012028 cites W2115358726 @default.
• W2082012028 cites W2118146014 @default.
• W2082012028 cites W2162501655 @default.
• W2082012028 cites W2165772152 @default.
• W2082012028 cites W2170277652 @default.
• W2082012028 cites W2171886226 @default.
• W2082012028 cites W2318297363 @default.
• W2082012028 cites W2322355512 @default.
• W2082012028 cites W2597070792 @default.
• W2082012028 doi "https://doi.org/10.4187/respcare.02806" @default.
• W2082012028 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24368862" @default.
• W2082012028 hasPublicationYear "2013" @default.
• W2082012028 type Work @default.
• W2082012028 sameAs 2082012028 @default.
• W2082012028 citedByCount "15" @default.
• W2082012028 countsByYear W20820120282015 @default.
• W2082012028 countsByYear W20820120282016 @default.
• W2082012028 countsByYear W20820120282017 @default.
• W2082012028 countsByYear W20820120282019 @default.
• W2082012028 countsByYear W20820120282020 @default.
• W2082012028 countsByYear W20820120282021 @default.
• W2082012028 countsByYear W20820120282022 @default.
• W2082012028 countsByYear W20820120282023 @default.
• W2082012028 crossrefType "journal-article" @default.
• W2082012028 hasAuthorship W2082012028A5006055654 @default.
• W2082012028 hasAuthorship W2082012028A5037209289 @default.
• W2082012028 hasAuthorship W2082012028A5040729990 @default.
• W2082012028 hasAuthorship W2082012028A5075768180 @default.
• W2082012028 hasAuthorship W2082012028A5085020072 @default.
• W2082012028 hasAuthorship W2082012028A5086572473 @default.
• W2082012028 hasAuthorship W2082012028A5091230938 @default.
• W2082012028 hasBestOaLocation W20820120281 @default.
• W2082012028 hasConcept C2780124106 @default.
• W2082012028 hasConcept C42219234 @default.
• W2082012028 hasConcept C71924100 @default.
• W2082012028 hasConceptScore W2082012028C2780124106 @default.
• W2082012028 hasConceptScore W2082012028C42219234 @default.
• W2082012028 hasConceptScore W2082012028C71924100 @default.
• W2082012028 hasIssue "8" @default.
• W2082012028 hasLocation W20820120281 @default.
• W2082012028 hasLocation W20820120282 @default.
• W2082012028 hasLocation W20820120283 @default.
• W2082012028 hasOpenAccess W2082012028 @default.
• W2082012028 hasPrimaryLocation W20820120281 @default.
• W2082012028 hasRelatedWork W1506200166 @default.
• W2082012028 hasRelatedWork W1995515455 @default.
• W2082012028 hasRelatedWork W2048182022 @default.
• W2082012028 hasRelatedWork W2080531066 @default.
• W2082012028 hasRelatedWork W2748952813 @default.
• W2082012028 hasRelatedWork W2899084033 @default.
• W2082012028 hasRelatedWork W3031052312 @default.
• W2082012028 hasRelatedWork W3032375762 @default.
• W2082012028 hasRelatedWork W3108674512 @default.
• W2082012028 hasRelatedWork W4322727716 @default.
• W2082012028 hasVolume "59" @default.
• W2082012028 isParatext "false" @default.
• W2082012028 isRetracted "false" @default.
• W2082012028 magId "2082012028" @default.
• W2082012028 workType "article" @default.