Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082056536> ?p ?o ?g. }
- W2082056536 endingPage "260" @default.
- W2082056536 startingPage "249" @default.
- W2082056536 abstract "Cell adhesion and communication are interdependent aspects of cell behavior that are critical for morphogenesis and tissue architecture. In the skin, epidermal adhesion is mediated in part by specialized cell-cell junctions known as desmosomes, which are characterized by the presence of desmosomal cadherins, known as desmogleins and desmocollins. We identified a cadherin family member, desmoglein 4, which is expressed in the suprabasal epidermis and hair follicle. The essential role of desmoglein 4 in skin was established by identifying mutations in families with inherited hypotrichosis, as well as in the lanceolate hair mouse. We also show that DSG4 is an autoantigen in pemphigus vulgaris. Characterization of the phenotype of naturally occurring mutant mice revealed disruption of desmosomal adhesion and perturbations in keratinocyte behavior. We provide evidence that desmoglein 4 is a key mediator of keratinocyte cell adhesion in the hair follicle, where it coordinates the transition from proliferation to differentiation." @default.
- W2082056536 created "2016-06-24" @default.
- W2082056536 creator A5000638570 @default.
- W2082056536 creator A5004582329 @default.
- W2082056536 creator A5022409621 @default.
- W2082056536 creator A5028018778 @default.
- W2082056536 creator A5031368365 @default.
- W2082056536 creator A5031861792 @default.
- W2082056536 creator A5032533037 @default.
- W2082056536 creator A5035081543 @default.
- W2082056536 creator A5040472184 @default.
- W2082056536 creator A5042072885 @default.
- W2082056536 creator A5042446012 @default.
- W2082056536 creator A5044165610 @default.
- W2082056536 creator A5044490713 @default.
- W2082056536 creator A5049338658 @default.
- W2082056536 creator A5057489242 @default.
- W2082056536 creator A5065755081 @default.
- W2082056536 creator A5072310267 @default.
- W2082056536 creator A5074884431 @default.
- W2082056536 creator A5077319281 @default.
- W2082056536 creator A5088224374 @default.
- W2082056536 creator A5090007539 @default.
- W2082056536 date "2003-04-01" @default.
- W2082056536 modified "2023-10-17" @default.
- W2082056536 title "Desmoglein 4 in Hair Follicle Differentiation and Epidermal Adhesion" @default.
- W2082056536 cites W1566822031 @default.
- W2082056536 cites W1609524256 @default.
- W2082056536 cites W1873268238 @default.
- W2082056536 cites W1979814807 @default.
- W2082056536 cites W1984724202 @default.
- W2082056536 cites W1990669035 @default.
- W2082056536 cites W1990798651 @default.
- W2082056536 cites W2006756873 @default.
- W2082056536 cites W2011498938 @default.
- W2082056536 cites W2015369395 @default.
- W2082056536 cites W2017372544 @default.
- W2082056536 cites W2017428806 @default.
- W2082056536 cites W2019720769 @default.
- W2082056536 cites W2028851968 @default.
- W2082056536 cites W2033177640 @default.
- W2082056536 cites W2036949285 @default.
- W2082056536 cites W2045091655 @default.
- W2082056536 cites W2059032249 @default.
- W2082056536 cites W2061419466 @default.
- W2082056536 cites W2064553526 @default.
- W2082056536 cites W2073171596 @default.
- W2082056536 cites W2077890930 @default.
- W2082056536 cites W2085379791 @default.
- W2082056536 cites W2086296240 @default.
- W2082056536 cites W2087743593 @default.
- W2082056536 cites W2088318175 @default.
- W2082056536 cites W2106791166 @default.
- W2082056536 cites W2107374823 @default.
- W2082056536 cites W2109276727 @default.
- W2082056536 cites W2116239421 @default.
- W2082056536 cites W2127124640 @default.
- W2082056536 cites W2139781265 @default.
- W2082056536 cites W2140643841 @default.
- W2082056536 cites W2141411672 @default.
- W2082056536 cites W2144891441 @default.
- W2082056536 cites W2147532402 @default.
- W2082056536 cites W2150104849 @default.
- W2082056536 cites W2152004578 @default.
- W2082056536 cites W2158579288 @default.
- W2082056536 cites W2164158459 @default.
- W2082056536 cites W2315200576 @default.
- W2082056536 cites W248609722 @default.
- W2082056536 cites W4245809956 @default.
- W2082056536 cites W4251072180 @default.
- W2082056536 doi "https://doi.org/10.1016/s0092-8674(03)00273-3" @default.
- W2082056536 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12705872" @default.
- W2082056536 hasPublicationYear "2003" @default.
- W2082056536 type Work @default.
- W2082056536 sameAs 2082056536 @default.
- W2082056536 citedByCount "298" @default.
- W2082056536 countsByYear W20820565362012 @default.
- W2082056536 countsByYear W20820565362013 @default.
- W2082056536 countsByYear W20820565362014 @default.
- W2082056536 countsByYear W20820565362015 @default.
- W2082056536 countsByYear W20820565362016 @default.
- W2082056536 countsByYear W20820565362017 @default.
- W2082056536 countsByYear W20820565362018 @default.
- W2082056536 countsByYear W20820565362019 @default.
- W2082056536 countsByYear W20820565362020 @default.
- W2082056536 countsByYear W20820565362021 @default.
- W2082056536 countsByYear W20820565362022 @default.
- W2082056536 countsByYear W20820565362023 @default.
- W2082056536 crossrefType "journal-article" @default.
- W2082056536 hasAuthorship W2082056536A5000638570 @default.
- W2082056536 hasAuthorship W2082056536A5004582329 @default.
- W2082056536 hasAuthorship W2082056536A5022409621 @default.
- W2082056536 hasAuthorship W2082056536A5028018778 @default.
- W2082056536 hasAuthorship W2082056536A5031368365 @default.
- W2082056536 hasAuthorship W2082056536A5031861792 @default.
- W2082056536 hasAuthorship W2082056536A5032533037 @default.
- W2082056536 hasAuthorship W2082056536A5035081543 @default.
- W2082056536 hasAuthorship W2082056536A5040472184 @default.