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- W2082087708 abstract "In order to investigate the role of gravity in a novel cancer treatment strategy called Gas Embolotherapy, we have computationally studied the evolution dynamics of two bubbles sticking to and sliding on the opposite walls of a 2D channel, under gravity-driven flow. We have modeled the moving three-phase contact lines using Tanner laws including contact angle hysteresis and have accounted for the gas-liquid interfacial dynamics in our model. Our model uses a Boundary Element Method (BEM) based moving-interface, multi-domain, iterative method to compute the flows and stresses on the domain boundaries at various instants of time. Since the normal and shear stresses acting on the endothelial layer of blood vessels are a major concern in the development of gas embolotherapy, we have examined the effect of bubble evolution and induced flows on the wall stresses. For a range of initial bubble pressures, we have studied the role of gravity by varying the Bond number and by using two different inclinations of the..." @default.
- W2082087708 created "2016-06-24" @default.
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- W2082087708 date "2010-06-01" @default.
- W2082087708 modified "2023-09-27" @default.
- W2082087708 title "A Boundary Element Model of Multiple Microcirculatory Bubbles in Cardiovasculature" @default.
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- W2082087708 doi "https://doi.org/10.1260/1756-8315.2.2-3.143" @default.
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