FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082128646> ?p ?o ?g. }

• W2082128646 endingPage "133" @default.
• W2082128646 startingPage "126" @default.
• W2082128646 abstract "Background— Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy (ARVD/C) Diagnostic Task Force Criteria (TFC) proposed in 1994 are highly specific but lack sensitivity. A new international task force modified criteria to improve diagnostic yield. A comparison of diagnosis by 1994 TFC versus newly proposed criteria in 3 patient groups was conducted. Methods and Results— In new TFC, scoring by major and minor criteria is maintained. Structural abnormalities are quantified and TFC highly specific for ARVD/C upgraded to major. Furthermore, new criteria are added: terminal activation duration of QRS ≥55 ms, ventricular tachycardia with left bundle-branch block morphology and superior axis, and genetic criteria. Three groups were studied: (1) 105 patients with proven ARVD/C according to 1994 TFC, (2) 89 of their family members, and (3) 39 patients with probable ARVD/C (ie, 3 points by 1994 TFC). All were screened for pathogenic mutations in desmosomal genes. Three ARVD/C patients did not meet the new sharpened criteria on structural abnormalities and thereby did not fulfill new TFC. In 62 of 105 patients with proven ARVD/C, mutations were found: 58 in the gene encoding Plakophilin2 ( PKP2 ), 3 in Desmoglein2, 3 in Desmocollin2, and 1 in Desmoplakin. Three patients had bigenic involvement. Ten additional relatives (11%) fulfilled new TFC: 9 (90%) were female, and all carried PKP2 mutations. No relatives lost diagnosis by application of new TFC. Of patients with probable ARVD/C, 25 (64%) fulfilled new TFC: 8 (40%) women and 14 (56%) carrying pathogenic mutations. Conclusions— In this first study applying new TFC to patients suspected of ARVD/C, 64% of probable ARVD/C patients and 11% of family members were additionally diagnosed. ECG criteria and pathogenic mutations especially contributed to new diagnosis. Newly proposed TFC have a major impact in increasing diagnostic yield of ARVD/C." @default.
• W2082128646 created "2016-06-24" @default.
• W2082128646 creator A5002151074 @default.
• W2082128646 creator A5008850936 @default.
• W2082128646 creator A5016961737 @default.
• W2082128646 creator A5017839586 @default.
• W2082128646 creator A5022941175 @default.
• W2082128646 creator A5024565033 @default.
• W2082128646 creator A5029273570 @default.
• W2082128646 creator A5037294241 @default.
• W2082128646 creator A5038816338 @default.
• W2082128646 creator A5044679752 @default.
• W2082128646 creator A5045837453 @default.
• W2082128646 creator A5050511817 @default.
• W2082128646 creator A5051983330 @default.
• W2082128646 creator A5059817891 @default.
• W2082128646 creator A5061063096 @default.
• W2082128646 creator A5087108967 @default.
• W2082128646 creator A5090144452 @default.
• W2082128646 date "2010-04-01" @default.
• W2082128646 modified "2023-10-18" @default.
• W2082128646 title "Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Diagnostic Task Force Criteria" @default.
• W2082128646 cites W1252778408 @default.
• W2082128646 cites W1969774384 @default.
• W2082128646 cites W1973928296 @default.
• W2082128646 cites W2002418172 @default.
• W2082128646 cites W2013670958 @default.
• W2082128646 cites W2019992253 @default.
• W2082128646 cites W2023634656 @default.
• W2082128646 cites W2036211423 @default.
• W2082128646 cites W2038373522 @default.
• W2082128646 cites W2046447203 @default.
• W2082128646 cites W2077186284 @default.
• W2082128646 cites W2094658226 @default.
• W2082128646 cites W2096649339 @default.
• W2082128646 cites W2100567991 @default.
• W2082128646 cites W2100750156 @default.
• W2082128646 cites W2101389618 @default.
• W2082128646 cites W2106899923 @default.
• W2082128646 cites W2121778435 @default.
• W2082128646 cites W2126286819 @default.
• W2082128646 cites W2127986488 @default.
• W2082128646 cites W2137677622 @default.
• W2082128646 cites W2138839726 @default.
• W2082128646 cites W2139781265 @default.
• W2082128646 cites W2154148336 @default.
• W2082128646 cites W2155110236 @default.
• W2082128646 cites W2165574770 @default.
• W2082128646 cites W2169350318 @default.
• W2082128646 cites W2170082059 @default.
• W2082128646 doi "https://doi.org/10.1161/circep.109.927202" @default.
• W2082128646 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20215590" @default.
• W2082128646 hasPublicationYear "2010" @default.
• W2082128646 type Work @default.
• W2082128646 sameAs 2082128646 @default.
• W2082128646 citedByCount "64" @default.
• W2082128646 countsByYear W20821286462012 @default.
• W2082128646 countsByYear W20821286462013 @default.
• W2082128646 countsByYear W20821286462014 @default.
• W2082128646 countsByYear W20821286462015 @default.
• W2082128646 countsByYear W20821286462016 @default.
• W2082128646 countsByYear W20821286462017 @default.
• W2082128646 countsByYear W20821286462018 @default.
• W2082128646 countsByYear W20821286462019 @default.
• W2082128646 countsByYear W20821286462020 @default.
• W2082128646 countsByYear W20821286462021 @default.
• W2082128646 countsByYear W20821286462022 @default.
• W2082128646 crossrefType "journal-article" @default.
• W2082128646 hasAuthorship W2082128646A5002151074 @default.
• W2082128646 hasAuthorship W2082128646A5008850936 @default.
• W2082128646 hasAuthorship W2082128646A5016961737 @default.
• W2082128646 hasAuthorship W2082128646A5017839586 @default.
• W2082128646 hasAuthorship W2082128646A5022941175 @default.
• W2082128646 hasAuthorship W2082128646A5024565033 @default.
• W2082128646 hasAuthorship W2082128646A5029273570 @default.
• W2082128646 hasAuthorship W2082128646A5037294241 @default.
• W2082128646 hasAuthorship W2082128646A5038816338 @default.
• W2082128646 hasAuthorship W2082128646A5044679752 @default.
• W2082128646 hasAuthorship W2082128646A5045837453 @default.
• W2082128646 hasAuthorship W2082128646A5050511817 @default.
• W2082128646 hasAuthorship W2082128646A5051983330 @default.
• W2082128646 hasAuthorship W2082128646A5059817891 @default.
• W2082128646 hasAuthorship W2082128646A5061063096 @default.
• W2082128646 hasAuthorship W2082128646A5087108967 @default.
• W2082128646 hasAuthorship W2082128646A5090144452 @default.
• W2082128646 hasBestOaLocation W20821286461 @default.
• W2082128646 hasConcept C126322002 @default.
• W2082128646 hasConcept C164705383 @default.
• W2082128646 hasConcept C17744445 @default.
• W2082128646 hasConcept C2777473070 @default.
• W2082128646 hasConcept C2777892804 @default.
• W2082128646 hasConcept C2778198053 @default.
• W2082128646 hasConcept C2778797674 @default.
• W2082128646 hasConcept C2780283014 @default.
• W2082128646 hasConcept C2985871740 @default.
• W2082128646 hasConcept C3116431 @default.
• W2082128646 hasConcept C71924100 @default.
• W2082128646 hasConceptScore W2082128646C126322002 @default.

• next