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- W2082157165 abstract "Summary. We found three truncated p53 transcipts in a patient with chronic myelogenous leukaemia in blast crisis carrying chromosome 17 abnormalities. Sequencing of these transcripts revealed complete absence of the entire exons 7, 8 and 9 in one, exons 8 and 9 in another, and exon 10 in the other. Sequencing analysis of genomic DNA, however, revealed no mutation in exons 6-10 and their flanking introns. These results suggest that the aberrant p53 transcripts in this case might not result from splicing mutations but from an unknown affected splicing process." @default.
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- W2082157165 date "1994-08-01" @default.
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- W2082157165 title "Multiple aberrant splicing of the p53 transcript without genomic mutations around exon-intron junctions in a case of chronic myelogenous leukaemia in blast crisis: a possible novel mechanism of p53 inactivation" @default.
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- W2082157165 doi "https://doi.org/10.1111/j.1365-2141.1994.tb06747.x" @default.
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