Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082192835> ?p ?o ?g. }
- W2082192835 endingPage "1079" @default.
- W2082192835 startingPage "1066" @default.
- W2082192835 abstract "A lipid bilayer deposited on an electrode surface can serve as a benchmark system to investigate lipid-protein interactions in the presence of physiological electric fields. Recoverin and myelin-associated glycoprotein (MAG) are used to study the impact of strong and weak protein-lipid interactions on the structure of model lipid bilayers, respectively. The structural changes in lipid bilayers are followed using electrochemical polarization modulation infrared reflection-absorption spectroscopy (PM IRRAS). Recoverin contains a myristoyl group that anchors in the hydrophobic part of a cell membrane. Insertion of the protein into the 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (DMPC)-cholesterol lipid bilayer leads to an increase in the capacitance of the lipid film adsorbed on a gold electrode surface. The stability and kinetics of the electric-field-driven adsorption-desorption process are not affected by the interaction with protein. Upon interaction with recoverin, the hydrophobic hydrocarbon chains become less ordered. The polar head groups are separated from each other, which allows for recoverin association in the membrane. MAG is known to interact with glycolipids present on the surface of a cell membrane. Upon probing the interaction of the DMPC-cholesterol-glycolipid bilayer with MAG a slight decrease in the capacity of the adsorbed lipid film is observed. The stability of the lipid bilayer increases towards negative potentials. At the molecular scale this interaction results in minor changes in the structure of the lipid bilayer. MAG causes small ordering in the hydrocarbon chains region and an increase in the hydration of the polar head groups. Combining an electrochemical approach with a structure-sensitive technique, such as PM IRRAS, is a powerful tool to follow small but significant changes in the structure of a supramolecular assembly." @default.
- W2082192835 created "2016-06-24" @default.
- W2082192835 creator A5039901888 @default.
- W2082192835 creator A5048456400 @default.
- W2082192835 creator A5057357802 @default.
- W2082192835 creator A5069886485 @default.
- W2082192835 creator A5070167637 @default.
- W2082192835 creator A5076567062 @default.
- W2082192835 date "2011-03-25" @default.
- W2082192835 modified "2023-10-16" @default.
- W2082192835 title "Impact of Strong and Weak Lipid-Protein Interactions on the Structure of a Lipid Bilayer on a Gold Electrode Surface" @default.
- W2082192835 cites W1206713406 @default.
- W2082192835 cites W1546405873 @default.
- W2082192835 cites W1562919767 @default.
- W2082192835 cites W1566113502 @default.
- W2082192835 cites W1584403942 @default.
- W2082192835 cites W1586738217 @default.
- W2082192835 cites W1601396769 @default.
- W2082192835 cites W1641556734 @default.
- W2082192835 cites W1670420367 @default.
- W2082192835 cites W1858234177 @default.
- W2082192835 cites W1966498960 @default.
- W2082192835 cites W1971866561 @default.
- W2082192835 cites W1973375372 @default.
- W2082192835 cites W1973998213 @default.
- W2082192835 cites W1975038690 @default.
- W2082192835 cites W1975246736 @default.
- W2082192835 cites W1980302794 @default.
- W2082192835 cites W1980305758 @default.
- W2082192835 cites W1980747645 @default.
- W2082192835 cites W1981539461 @default.
- W2082192835 cites W1984030246 @default.
- W2082192835 cites W1984156785 @default.
- W2082192835 cites W1986617615 @default.
- W2082192835 cites W1989043041 @default.
- W2082192835 cites W1991296357 @default.
- W2082192835 cites W1992045220 @default.
- W2082192835 cites W1993578376 @default.
- W2082192835 cites W1994387300 @default.
- W2082192835 cites W1995247662 @default.
- W2082192835 cites W1999554227 @default.
- W2082192835 cites W2001511531 @default.
- W2082192835 cites W2011589842 @default.
- W2082192835 cites W2012233471 @default.
- W2082192835 cites W2013287900 @default.
- W2082192835 cites W2014126179 @default.
- W2082192835 cites W2015423235 @default.
- W2082192835 cites W2015463719 @default.
- W2082192835 cites W2016326704 @default.
- W2082192835 cites W2016567150 @default.
- W2082192835 cites W2016849856 @default.
- W2082192835 cites W2017033865 @default.
- W2082192835 cites W2019883183 @default.
- W2082192835 cites W2020295187 @default.
- W2082192835 cites W2022256983 @default.
- W2082192835 cites W2022425508 @default.
- W2082192835 cites W2026376788 @default.
- W2082192835 cites W2028045919 @default.
- W2082192835 cites W2028758362 @default.
- W2082192835 cites W2031403719 @default.
- W2082192835 cites W2031850930 @default.
- W2082192835 cites W2036164670 @default.
- W2082192835 cites W2037655288 @default.
- W2082192835 cites W2042074864 @default.
- W2082192835 cites W2047810853 @default.
- W2082192835 cites W2060548005 @default.
- W2082192835 cites W2062298836 @default.
- W2082192835 cites W2062718138 @default.
- W2082192835 cites W2062759144 @default.
- W2082192835 cites W2063537903 @default.
- W2082192835 cites W2066181699 @default.
- W2082192835 cites W2067504163 @default.
- W2082192835 cites W2068341834 @default.
- W2082192835 cites W2072114159 @default.
- W2082192835 cites W2076820350 @default.
- W2082192835 cites W2077946227 @default.
- W2082192835 cites W2079287985 @default.
- W2082192835 cites W2080333994 @default.
- W2082192835 cites W2080868570 @default.
- W2082192835 cites W2081653633 @default.
- W2082192835 cites W2084524162 @default.
- W2082192835 cites W2088027496 @default.
- W2082192835 cites W2088107416 @default.
- W2082192835 cites W2092173694 @default.
- W2082192835 cites W2095096053 @default.
- W2082192835 cites W2098062600 @default.
- W2082192835 cites W2105257219 @default.
- W2082192835 cites W2122608961 @default.
- W2082192835 cites W2133874606 @default.
- W2082192835 cites W2148932927 @default.
- W2082192835 cites W2162053418 @default.
- W2082192835 cites W2178669379 @default.
- W2082192835 cites W2236762033 @default.
- W2082192835 cites W4235809796 @default.
- W2082192835 cites W4241068331 @default.
- W2082192835 cites W4300647540 @default.
- W2082192835 doi "https://doi.org/10.1002/cphc.201100036" @default.
- W2082192835 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21442718" @default.