FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082205722> ?p ?o ?g. }

• W2082205722 endingPage "1257" @default.
• W2082205722 startingPage "1257" @default.
• W2082205722 abstract "To compare ofloxacin solution with a combination of fortified antibiotic cefazolin sodium and tobramycin sulfate solutions in the treatment of bacterial keratitis.Patients under care at any one of 28 participating clinical centers who had an eye with suspected bacterial keratitis were randomly allocated in a double-masked manner to treatment with 0.3% ofloxacin solution or a combination of the fortified antibiotics (1.5% tobramycin and 10.0% cefazolin solutions).Time to healing defined as complete re-epithelization, accompanied by a nonprogressive stromal infiltrate for two consecutive visits. Secondary outcome measures included patient symptoms and signs of infection and adverse reactions to study medications. Only patients with a positive bacterial corneal culture were included in most analyses.A positive bacterial corneal culture was obtained in 140 (56%) of the 248 enrolled patients. The time to healing was similar among the 73 patients receiving ofloxacin and the 67 patients receiving fortified antibiotics (P = .70). By 7 days after study entry, the keratitis in 37% of the ofloxacin group and 38% of the fortified antibiotics group had healed. By 28 days, keratitis in 89% of the ofloxacin group and 86% of the fortified antibiotics group had healed. Two patients receiving ofloxacin and one receiving fortified antibiotics discontinued study medication because of lack of efficacy. Patients receiving ofloxacin reported substantially less burning and stinging on instillation than the patients receiving fortified antibiotics (P < .001). Five of six patients among the 140 with positive bacterial cultures who had study medications discontinued because of ocular side effects were in the fortified antibiotics group; an additional three patients, all in the fortified antibiotics group, among the remaining 108 receiving study medications had ocular side effects.The efficacy of ofloxacin solution in treating bacterial keratitis is equivalent to that of the fortified cefazolin and tobramycin solutions. The reduced frequency of ocular toxic effects and the relative ease of preparation of ofloxacin are additional considerations." @default.
• W2082205722 created "2016-06-24" @default.
• W2082205722 creator A5065318636 @default.
• W2082205722 date "1995-10-01" @default.
• W2082205722 modified "2023-10-18" @default.
• W2082205722 title "Efficacy of Ofloxacin vs Cefazolin and Tobramycin in the Therapy for Bacterial Keratitis" @default.
• W2082205722 cites W105156579 @default.
• W2082205722 cites W128488591 @default.
• W2082205722 cites W1483931223 @default.
• W2082205722 cites W1580788756 @default.
• W2082205722 cites W164610877 @default.
• W2082205722 cites W1965392945 @default.
• W2082205722 cites W1966138471 @default.
• W2082205722 cites W1972226672 @default.
• W2082205722 cites W1978009035 @default.
• W2082205722 cites W1978136073 @default.
• W2082205722 cites W1979158308 @default.
• W2082205722 cites W1979300931 @default.
• W2082205722 cites W1991533929 @default.
• W2082205722 cites W2004811917 @default.
• W2082205722 cites W2006698976 @default.
• W2082205722 cites W2011172868 @default.
• W2082205722 cites W2014530124 @default.
• W2082205722 cites W2026281986 @default.
• W2082205722 cites W2030507835 @default.
• W2082205722 cites W2033063747 @default.
• W2082205722 cites W2052855464 @default.
• W2082205722 cites W2068854103 @default.
• W2082205722 cites W2082958951 @default.
• W2082205722 cites W2088783507 @default.
• W2082205722 cites W2155198260 @default.
• W2082205722 cites W2398949925 @default.
• W2082205722 cites W2413347365 @default.
• W2082205722 cites W2484460550 @default.
• W2082205722 doi "https://doi.org/10.1001/archopht.1995.01100100045026" @default.
• W2082205722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7575256" @default.
• W2082205722 hasPublicationYear "1995" @default.
• W2082205722 type Work @default.
• W2082205722 sameAs 2082205722 @default.
• W2082205722 citedByCount "214" @default.
• W2082205722 countsByYear W20822057222012 @default.
• W2082205722 countsByYear W20822057222013 @default.
• W2082205722 countsByYear W20822057222014 @default.
• W2082205722 countsByYear W20822057222015 @default.
• W2082205722 countsByYear W20822057222016 @default.
• W2082205722 countsByYear W20822057222017 @default.
• W2082205722 countsByYear W20822057222018 @default.
• W2082205722 countsByYear W20822057222019 @default.
• W2082205722 countsByYear W20822057222020 @default.
• W2082205722 countsByYear W20822057222021 @default.
• W2082205722 countsByYear W20822057222022 @default.
• W2082205722 countsByYear W20822057222023 @default.
• W2082205722 crossrefType "journal-article" @default.
• W2082205722 hasAuthorship W2082205722A5065318636 @default.
• W2082205722 hasConcept C118487528 @default.
• W2082205722 hasConcept C126322002 @default.
• W2082205722 hasConcept C141071460 @default.
• W2082205722 hasConcept C2775832221 @default.
• W2082205722 hasConcept C2778049240 @default.
• W2082205722 hasConcept C2778353156 @default.
• W2082205722 hasConcept C2778512257 @default.
• W2082205722 hasConcept C2778560704 @default.
• W2082205722 hasConcept C2778974779 @default.
• W2082205722 hasConcept C501593827 @default.
• W2082205722 hasConcept C71924100 @default.
• W2082205722 hasConcept C86803240 @default.
• W2082205722 hasConcept C89423630 @default.
• W2082205722 hasConceptScore W2082205722C118487528 @default.
• W2082205722 hasConceptScore W2082205722C126322002 @default.
• W2082205722 hasConceptScore W2082205722C141071460 @default.
• W2082205722 hasConceptScore W2082205722C2775832221 @default.
• W2082205722 hasConceptScore W2082205722C2778049240 @default.
• W2082205722 hasConceptScore W2082205722C2778353156 @default.
• W2082205722 hasConceptScore W2082205722C2778512257 @default.
• W2082205722 hasConceptScore W2082205722C2778560704 @default.
• W2082205722 hasConceptScore W2082205722C2778974779 @default.
• W2082205722 hasConceptScore W2082205722C501593827 @default.
• W2082205722 hasConceptScore W2082205722C71924100 @default.
• W2082205722 hasConceptScore W2082205722C86803240 @default.
• W2082205722 hasConceptScore W2082205722C89423630 @default.
• W2082205722 hasIssue "10" @default.
• W2082205722 hasLocation W20822057221 @default.
• W2082205722 hasLocation W20822057222 @default.
• W2082205722 hasOpenAccess W2082205722 @default.
• W2082205722 hasPrimaryLocation W20822057221 @default.
• W2082205722 hasRelatedWork W171433666 @default.
• W2082205722 hasRelatedWork W1984229806 @default.
• W2082205722 hasRelatedWork W1986496024 @default.
• W2082205722 hasRelatedWork W1999068812 @default.
• W2082205722 hasRelatedWork W20224748 @default.
• W2082205722 hasRelatedWork W2070627405 @default.
• W2082205722 hasRelatedWork W2073266950 @default.
• W2082205722 hasRelatedWork W2082205722 @default.
• W2082205722 hasRelatedWork W4246697004 @default.
• W2082205722 hasRelatedWork W2181720398 @default.
• W2082205722 hasVolume "113" @default.
• W2082205722 isParatext "false" @default.
• W2082205722 isRetracted "false" @default.

• next