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- W2082207907 abstract "David Shepro, PhD, ed 1732 pages. Burlington, Mass: Elsevier Academic Press; 2005. $299.00. ISBN 13:978–0–12–639510–5Microvascular Research: Biology and Pathology is a 2-volume compendium comprising 5 parts, 167 chapters, and nearly 1200 pages devoted to a detailed understanding of the microcirculation. The book is edited by David Shepro, PhD, and an editorial board that reads like the “who’s who” in microvascular research. The textbook takes a modern day approach to gathering, organizing, and reporting information in an outline form, cognizant that new information is being generated and published at a rate that exceeds its ability to be truly up to date. Rather, the authors have taken the approach of focusing on key principals and their experimental basis as the foundation for each chapter. The editors promise to provide updates through Web offerings when salient and novel findings are published, remedying the issue of a textbook that is out of date before it is published.In some cases, the respective chapters read as well-referenced outlines rather than comprehensive reviews. To the cognoscenti, such an approach may seem superficial, but to those whose scientific interests border on the field of microcirculation, the chapters are insightful and easily comprehensible, if not comprehensive.The initial section is devoted to cell biology and defines the role of the endothelium, extracellular matrix, and autocrine and paracrine factors in the genesis of the microcirculation. The fundamental roles of endothlin-1 and vascular endothelial growth factor and their signaling in microvascular regulation are presented. New developments with respect to the role of interleukin-7, classically considered a growth and antiapoptotic factor in T- and B-cell …" @default.
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- W2082207907 title "Microvascular Research: Biology and Pathology" @default.
- W2082207907 doi "https://doi.org/10.1161/circulationaha.105.605782" @default.
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