FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082288981> ?p ?o ?g. }

• W2082288981 abstract "Decreased upright cerebral blood flow (CBF) with hyperpnea and hypocapnia is seen in a minority of patients with postural tachycardia syndrome (POTS). More often, CBF is not decreased despite upright neurocognitive dysfunction. This may result from time-dependent changes in CBF. We hypothesized that increased oscillations in CBF occurs in POTS (N=12) compared to healthy controls (N=9), and tested by measuring CBF velocity (CBFv) by transcranial Doppler ultrasound of the middle cerebral artery, mean arterial pressure (MAP) and related parameters, supine and during 70o upright tilt. Autospectra for mean CBFv and MAP, and transfer function analysis were obtained over the frequency range of 0.0078 to 0.4 Hz. Upright HR was increased in POTS (125±8 vs 86±2 bpm), as was diastolic BP (74±3 vs 65±3 mmHg) compared to control, while peripheral resistance, cardiac output, and mean CBFv increased similarly with tilt. Upright BP variability (BPV), low frequency (LF) power (.04 - 0.13 Hz) , and peak frequency of BPV were increased in POTS (24.3±4.1, and 18.4±4.1 mmHg2/Hz at .091 Hz vs 11.8±3.3, and 8.8 ± 2 mmHg2/Hz c at 0.071 Hz), as was upright overall CBFv variability, low frequency power and peak frequency of CBFv variability (29.3±4.7, and 22.1±2.7 [cm/s]2/Hz at .092 Hz vs 14.7±2.6, and 6.7 ± 1.2 [cm/s]2/Hz at 0.077Hz). Autospectra were sharply peaked in POTS. LF phase was decreased in POTS (-14 ± 4 vs -25 ± 10 degrees) while upright. LF gain was increased (1.51 ± 0.09 vs 0.86 ± 0.12 [cm/s]/ mmHg) while coherence was increased (0.96 ± 0.01 vs 0.80 ± 0.04). Increased oscillatory BP in upright POTS patients is closely coupled to oscillatory CBFv over a narrow bandwidth corresponding to the Mayer wave frequency. Therefore combined increased oscillatory BP and increased LF gain markedly increases CBFv oscillations in a narrow bandwidth. This close coupling of CBF to MAP indicates impaired cerebral autoregulation that may underlie upright neurocognitive dysfunction in POTS." @default.
• W2082288981 created "2016-06-24" @default.
• W2082288981 creator A5032944582 @default.
• W2082288981 creator A5048258883 @default.
• W2082288981 creator A5066123311 @default.
• W2082288981 creator A5073854758 @default.
• W2082288981 creator A5078833076 @default.
• W2082288981 date "2014-06-23" @default.
• W2082288981 modified "2023-09-26" @default.
• W2082288981 title "Altered oscillatory cerebral blood flow velocity and autoregulation in postural tachycardia syndrome" @default.
• W2082288981 cites W1600275345 @default.
• W2082288981 cites W1731997554 @default.
• W2082288981 cites W1987706407 @default.
• W2082288981 cites W1997275331 @default.
• W2082288981 cites W2000659208 @default.
• W2082288981 cites W2013070592 @default.
• W2082288981 cites W2021945392 @default.
• W2082288981 cites W2022121530 @default.
• W2082288981 cites W2022385223 @default.
• W2082288981 cites W2034959806 @default.
• W2082288981 cites W2035196865 @default.
• W2082288981 cites W2036253606 @default.
• W2082288981 cites W2036922356 @default.
• W2082288981 cites W2042360472 @default.
• W2082288981 cites W2042730494 @default.
• W2082288981 cites W2044192936 @default.
• W2082288981 cites W2044420365 @default.
• W2082288981 cites W2044770073 @default.
• W2082288981 cites W2045199364 @default.
• W2082288981 cites W2045445225 @default.
• W2082288981 cites W2062701996 @default.
• W2082288981 cites W2066874389 @default.
• W2082288981 cites W2071853069 @default.
• W2082288981 cites W2073950908 @default.
• W2082288981 cites W2079310325 @default.
• W2082288981 cites W2085302484 @default.
• W2082288981 cites W2094429459 @default.
• W2082288981 cites W2095077755 @default.
• W2082288981 cites W2095748649 @default.
• W2082288981 cites W2095800632 @default.
• W2082288981 cites W2097388615 @default.
• W2082288981 cites W2098914003 @default.
• W2082288981 cites W2104164572 @default.
• W2082288981 cites W2106822551 @default.
• W2082288981 cites W2120609490 @default.
• W2082288981 cites W2121934251 @default.
• W2082288981 cites W2127352491 @default.
• W2082288981 cites W2128828233 @default.
• W2082288981 cites W2131339291 @default.
• W2082288981 cites W2135620001 @default.
• W2082288981 cites W2135871023 @default.
• W2082288981 cites W2158439994 @default.
• W2082288981 cites W2159235182 @default.
• W2082288981 cites W2160694091 @default.
• W2082288981 cites W2164469018 @default.
• W2082288981 cites W2173135046 @default.
• W2082288981 cites W2309256480 @default.
• W2082288981 cites W4249033469 @default.
• W2082288981 cites W4298352105 @default.
• W2082288981 doi "https://doi.org/10.3389/fphys.2014.00234" @default.
• W2082288981 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4067089" @default.
• W2082288981 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25002851" @default.
• W2082288981 hasPublicationYear "2014" @default.
• W2082288981 type Work @default.
• W2082288981 sameAs 2082288981 @default.
• W2082288981 citedByCount "19" @default.
• W2082288981 countsByYear W20822889812015 @default.
• W2082288981 countsByYear W20822889812016 @default.
• W2082288981 countsByYear W20822889812017 @default.
• W2082288981 countsByYear W20822889812018 @default.
• W2082288981 countsByYear W20822889812019 @default.
• W2082288981 countsByYear W20822889812020 @default.
• W2082288981 countsByYear W20822889812021 @default.
• W2082288981 countsByYear W20822889812022 @default.
• W2082288981 crossrefType "journal-article" @default.
• W2082288981 hasAuthorship W2082288981A5032944582 @default.
• W2082288981 hasAuthorship W2082288981A5048258883 @default.
• W2082288981 hasAuthorship W2082288981A5066123311 @default.
• W2082288981 hasAuthorship W2082288981A5073854758 @default.
• W2082288981 hasAuthorship W2082288981A5078833076 @default.
• W2082288981 hasBestOaLocation W20822889811 @default.
• W2082288981 hasConcept C111774379 @default.
• W2082288981 hasConcept C125567185 @default.
• W2082288981 hasConcept C126322002 @default.
• W2082288981 hasConcept C157767197 @default.
• W2082288981 hasConcept C164705383 @default.
• W2082288981 hasConcept C191616109 @default.
• W2082288981 hasConcept C2775841333 @default.
• W2082288981 hasConcept C2777037550 @default.
• W2082288981 hasConcept C2778866228 @default.
• W2082288981 hasConcept C42219234 @default.
• W2082288981 hasConcept C534529494 @default.
• W2082288981 hasConcept C541997718 @default.
• W2082288981 hasConcept C71924100 @default.
• W2082288981 hasConcept C84359808 @default.
• W2082288981 hasConcept C84393581 @default.
• W2082288981 hasConceptScore W2082288981C111774379 @default.
• W2082288981 hasConceptScore W2082288981C125567185 @default.
• W2082288981 hasConceptScore W2082288981C126322002 @default.
• W2082288981 hasConceptScore W2082288981C157767197 @default.

• next