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• W2082304865 abstract "Cloned cDNA probes that recognize muscle-specific α-actin gene transcripts have been used to analyze two kinds of experimental embryos in Xenopus. In one, genetically marked nuclei of larval muscle cells were transplanted to wild-type enucleated eggs; α-actin genes became transcriptionally inactive in the resulting blastulae but were reactivated when these embryos reached the normal stage of α-actin expression (late gastrula). In the other, blastula embryos reared from fertilized eggs were separated into animal, vegetal, and equatorial regions, and their cells dissociated and reaggregated. α-Actin RNA was synthesized at the normal time in development, but only by equatorial cells. We conclude that α-actin gene transcription is normally regulated in nuclear-transplant embryos and is undisturbed by the absence of cell contacts during cleavage." @default.
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• W2082304865 date "1984-10-01" @default.
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• W2082304865 title "Transcription of muscle-specific actin genes in early xenopus development: Nuclear transplantation and cell dissociation" @default.
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• W2082304865 doi "https://doi.org/10.1016/0092-8674(84)90264-2" @default.
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