FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082324404> ?p ?o ?g. }

• W2082324404 endingPage "600" @default.
• W2082324404 startingPage "591" @default.
• W2082324404 abstract "Background: We have previously demonstrated that ethanol teratogenicity is associated with metallothionein‐induced fetal zinc (Zn) deficiency, and that maternal subcutaneous Zn treatment given with ethanol in early pregnancy prevents fetal abnormalities and spatial memory impairments in mice. Here we investigated whether dietary Zn supplementation throughout pregnancy can also prevent ethanol‐related dysmorphology. Methods: Pregnant mice were injected with saline or 25% ethanol (0.015 ml/g intraperitoneally at 0 and 4 hours) on gestational day (GD) 8 and fed either a control (35 mg Zn/kg) or a Zn‐supplemented diet (200 mg Zn/kg) from GD 0 to 18. Fetuses from the saline, saline + Zn, ethanol and ethanol + Zn groups were assessed for external birth abnormalities on GD 18. In a separate cohort of mice, postnatal growth and survival of offspring from these treatment groups were examined from birth until postnatal day 60. Results: Fetuses from dams treated with ethanol alone in early pregnancy had a significantly greater incidence of physical abnormalities (26%) compared to those from the saline (10%), saline + Zn (9%), or ethanol + Zn (12%) groups. The incidence of abnormalities in ethanol + Zn‐supplemented fetuses was not different from saline‐treated fetuses. While ethanol exposure did not affect the number of fetal resorptions or pre‐ or postnatal weight, there were more stillbirths with ethanol alone, and cumulative postnatal mortality was significantly higher in offspring exposed to ethanol alone (35% deaths) compared to all other treatment groups (13.5 to 20.5% deaths). Mice supplemented with Zn throughout pregnancy had higher plasma Zn concentrations than those in un‐supplemented groups. Conclusions: These findings demonstrate that dietary Zn supplementation throughout pregnancy ameliorates dysmorphology and postnatal mortality caused by ethanol exposure in early pregnancy." @default.
• W2082324404 created "2016-06-24" @default.
• W2082324404 creator A5033038197 @default.
• W2082324404 creator A5045287053 @default.
• W2082324404 creator A5089083023 @default.
• W2082324404 date "2009-03-25" @default.
• W2082324404 modified "2023-10-17" @default.
• W2082324404 title "Dietary Zinc Supplementation Throughout Pregnancy Protects Against Fetal Dysmorphology and Improves Postnatal Survival After Prenatal Ethanol Exposure in Mice" @default.
• W2082324404 cites W1509704113 @default.
• W2082324404 cites W1558878183 @default.
• W2082324404 cites W1585183194 @default.
• W2082324404 cites W1891922159 @default.
• W2082324404 cites W1895706734 @default.
• W2082324404 cites W1919108232 @default.
• W2082324404 cites W1964020041 @default.
• W2082324404 cites W1974120359 @default.
• W2082324404 cites W1979268276 @default.
• W2082324404 cites W1982031557 @default.
• W2082324404 cites W1982215705 @default.
• W2082324404 cites W1984540967 @default.
• W2082324404 cites W1986183892 @default.
• W2082324404 cites W1986492359 @default.
• W2082324404 cites W1987062717 @default.
• W2082324404 cites W1987826896 @default.
• W2082324404 cites W1995684690 @default.
• W2082324404 cites W2000906869 @default.
• W2082324404 cites W2003753368 @default.
• W2082324404 cites W2007389819 @default.
• W2082324404 cites W2011258416 @default.
• W2082324404 cites W2016907728 @default.
• W2082324404 cites W2018623236 @default.
• W2082324404 cites W2021555474 @default.
• W2082324404 cites W2026762290 @default.
• W2082324404 cites W2027955051 @default.
• W2082324404 cites W2029301296 @default.
• W2082324404 cites W2029932272 @default.
• W2082324404 cites W2032032976 @default.
• W2082324404 cites W2037538330 @default.
• W2082324404 cites W2040208650 @default.
• W2082324404 cites W2044118325 @default.
• W2082324404 cites W2048161650 @default.
• W2082324404 cites W2049698438 @default.
• W2082324404 cites W2051801328 @default.
• W2082324404 cites W2051892654 @default.
• W2082324404 cites W2052385802 @default.
• W2082324404 cites W2071743920 @default.
• W2082324404 cites W2073255901 @default.
• W2082324404 cites W2073960752 @default.
• W2082324404 cites W2082499884 @default.
• W2082324404 cites W2085287316 @default.
• W2082324404 cites W2085866221 @default.
• W2082324404 cites W2086809297 @default.
• W2082324404 cites W2087953327 @default.
• W2082324404 cites W2089920011 @default.
• W2082324404 cites W2092603433 @default.
• W2082324404 cites W2093594079 @default.
• W2082324404 cites W2100089767 @default.
• W2082324404 cites W2103199749 @default.
• W2082324404 cites W2104788447 @default.
• W2082324404 cites W2105803118 @default.
• W2082324404 cites W2110652761 @default.
• W2082324404 cites W2128934600 @default.
• W2082324404 cites W2145164012 @default.
• W2082324404 cites W2155775626 @default.
• W2082324404 cites W2161888905 @default.
• W2082324404 cites W2165592525 @default.
• W2082324404 cites W2320037076 @default.
• W2082324404 cites W2333866659 @default.
• W2082324404 cites W2412093151 @default.
• W2082324404 cites W4232344382 @default.
• W2082324404 cites W4232734394 @default.
• W2082324404 cites W4242843112 @default.
• W2082324404 cites W4244450487 @default.
• W2082324404 doi "https://doi.org/10.1111/j.1530-0277.2008.00873.x" @default.
• W2082324404 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19183140" @default.
• W2082324404 hasPublicationYear "2009" @default.
• W2082324404 type Work @default.
• W2082324404 sameAs 2082324404 @default.
• W2082324404 citedByCount "32" @default.
• W2082324404 countsByYear W20823244042012 @default.
• W2082324404 countsByYear W20823244042013 @default.
• W2082324404 countsByYear W20823244042014 @default.
• W2082324404 countsByYear W20823244042015 @default.
• W2082324404 countsByYear W20823244042016 @default.
• W2082324404 countsByYear W20823244042018 @default.
• W2082324404 countsByYear W20823244042021 @default.
• W2082324404 countsByYear W20823244042022 @default.
• W2082324404 countsByYear W20823244042023 @default.
• W2082324404 crossrefType "journal-article" @default.
• W2082324404 hasAuthorship W2082324404A5033038197 @default.
• W2082324404 hasAuthorship W2082324404A5045287053 @default.
• W2082324404 hasAuthorship W2082324404A5089083023 @default.
• W2082324404 hasConcept C112672928 @default.
• W2082324404 hasConcept C126322002 @default.
• W2082324404 hasConcept C134018914 @default.
• W2082324404 hasConcept C172680121 @default.
• W2082324404 hasConcept C2777397205 @default.
• W2082324404 hasConcept C2777601104 @default.

• next