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• W2082381478 abstract "Gliomas that arise in the brain stem and other malignant gliomas constitute approximately 60% of all brain tumors and have eluded effective therapy, in part because they are able to infiltrate the normal brain. Histopathologic studies have confirmed the presence of infiltrating tumor cells very distant from the glioma mass. We review the neuroimaging and pathologic features of glioma-cell infiltration and some of the complex cellular and biochemical determinants of tumor-cell motility and invasiveness. Understanding how glioma cells become motile and invasive is pivotal to therapeutically targeting the machinery that enables gliomas to infiltrate the brain. (J Child Neurol 1993;8:292-305)." @default.
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• W2082381478 date "1993-10-01" @default.
• W2082381478 modified "2023-09-23" @default.
• W2082381478 title "Topical Review Article: Brainstem and Other Malignant Gliomas: II. Possible Mechanisms of Brain Infiltration by Tumor Cells" @default.
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• W2082381478 doi "https://doi.org/10.1177/088307389300800402" @default.
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