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- W2082400577 endingPage "932" @default.
- W2082400577 startingPage "901" @default.
- W2082400577 abstract "Increasing evidence suggests that natriuretic peptides (NPs) play diverse roles in mammals, including renal hemodynamics, neuroendocrine, and cardiovascular functions. Collectively, NPs are classified as hypotensive hormones; the main actions of NPs are implicated in eliciting natriuretic, diuretic, steroidogenic, antiproliferative, and vasorelaxant effects, important factors in the control of body fluid volume and blood pressure homeostasis. One of the principal loci involved in the regulatory actions of NPs is their cognate plasma membrane receptor molecules, which are activated by binding with specific NPs. Interaction of NPs with their receptors plays a central role in physiology and pathophysiology of hypertension and cardiovascular disorders. Gaining insight into the intricacies of NPs-specific receptor signaling pathways is of pivotal importance for understanding both hormone-receptor biology and the disease states arising from abnormal hormone receptor interplay. During the last decade there has been a surge in interest in NP receptors; consequently, a wealth of information has emerged concerning molecular structure and function, signaling mechanisms, and use of transgenics and gene-targeted mouse models. The objective of this present review is to summarize and document the previous findings and recent discoveries in the field of the natriuretic peptide hormone family and receptor systems with emphasis on the structure-function relationship, signaling mechanisms, and the physiological and pathophysiological significance in health and disease." @default.
- W2082400577 created "2016-06-24" @default.
- W2082400577 creator A5013084644 @default.
- W2082400577 date "2005-06-01" @default.
- W2082400577 modified "2023-09-30" @default.
- W2082400577 title "Biology of natriuretic peptides and their receptors" @default.
- W2082400577 cites W101207630 @default.
- W2082400577 cites W1485109611 @default.
- W2082400577 cites W148648419 @default.
- W2082400577 cites W1486853239 @default.
- W2082400577 cites W1493349125 @default.
- W2082400577 cites W1496216397 @default.
- W2082400577 cites W1500832403 @default.
- W2082400577 cites W1510010134 @default.
- W2082400577 cites W1511221661 @default.
- W2082400577 cites W1520611194 @default.
- W2082400577 cites W1525728123 @default.
- W2082400577 cites W1527490253 @default.
- W2082400577 cites W1540426111 @default.
- W2082400577 cites W1541662023 @default.
- W2082400577 cites W1542279315 @default.
- W2082400577 cites W1545530316 @default.
- W2082400577 cites W1552901871 @default.
- W2082400577 cites W1557907474 @default.
- W2082400577 cites W1558386025 @default.
- W2082400577 cites W1559048099 @default.
- W2082400577 cites W1564187709 @default.
- W2082400577 cites W1566921440 @default.
- W2082400577 cites W1574096163 @default.
- W2082400577 cites W1574889281 @default.
- W2082400577 cites W1577009981 @default.
- W2082400577 cites W1579015292 @default.
- W2082400577 cites W1579903794 @default.
- W2082400577 cites W1599050967 @default.
- W2082400577 cites W1599602246 @default.
- W2082400577 cites W1603467189 @default.
- W2082400577 cites W1603537849 @default.
- W2082400577 cites W1605314587 @default.
- W2082400577 cites W1607672162 @default.
- W2082400577 cites W1610892577 @default.
- W2082400577 cites W1630792128 @default.
- W2082400577 cites W1741421471 @default.
- W2082400577 cites W1775131150 @default.
- W2082400577 cites W1836582633 @default.
- W2082400577 cites W1905627889 @default.
- W2082400577 cites W1912249044 @default.
- W2082400577 cites W1944726467 @default.
- W2082400577 cites W1958657793 @default.
- W2082400577 cites W1963921468 @default.
- W2082400577 cites W1964194790 @default.
- W2082400577 cites W1964409706 @default.
- W2082400577 cites W1964541624 @default.
- W2082400577 cites W1964933592 @default.
- W2082400577 cites W1965647535 @default.
- W2082400577 cites W1966210234 @default.
- W2082400577 cites W1966513216 @default.
- W2082400577 cites W1966884133 @default.
- W2082400577 cites W1967210990 @default.
- W2082400577 cites W1967295182 @default.
- W2082400577 cites W1967404762 @default.
- W2082400577 cites W1968331622 @default.
- W2082400577 cites W1968341507 @default.
- W2082400577 cites W1968573434 @default.
- W2082400577 cites W1968747525 @default.
- W2082400577 cites W1970407496 @default.
- W2082400577 cites W1970429382 @default.
- W2082400577 cites W1970463377 @default.
- W2082400577 cites W1970546352 @default.
- W2082400577 cites W1970970121 @default.
- W2082400577 cites W1971226432 @default.
- W2082400577 cites W1972616722 @default.
- W2082400577 cites W1972700689 @default.
- W2082400577 cites W1973363947 @default.
- W2082400577 cites W1973505268 @default.
- W2082400577 cites W1974847515 @default.
- W2082400577 cites W1975348615 @default.
- W2082400577 cites W1975728622 @default.
- W2082400577 cites W1975730039 @default.
- W2082400577 cites W1976134178 @default.
- W2082400577 cites W1976300627 @default.
- W2082400577 cites W1976353645 @default.
- W2082400577 cites W1977097733 @default.
- W2082400577 cites W1977186063 @default.
- W2082400577 cites W1977462706 @default.
- W2082400577 cites W1977787091 @default.
- W2082400577 cites W1978038902 @default.
- W2082400577 cites W1978411785 @default.
- W2082400577 cites W1978468242 @default.
- W2082400577 cites W1978573044 @default.
- W2082400577 cites W1979659033 @default.
- W2082400577 cites W1980214446 @default.
- W2082400577 cites W1980669305 @default.
- W2082400577 cites W1980946238 @default.
- W2082400577 cites W1981197421 @default.
- W2082400577 cites W1982621018 @default.
- W2082400577 cites W1983094993 @default.
- W2082400577 cites W1984092953 @default.
- W2082400577 cites W1984893737 @default.