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- W2082422182 abstract "A bioassay-guided fractionation and chemical examination of the soft coral Sinularia flexibilis resulted in the isolation and characterization of sinulaflexiolides A−K (1−11), along with sinulariolone (12), 5-dehydrosinularolide (13), capillolide (14), sinulariolide (15), 5,8-epoxy-9-acetoxysinulariolide (16), flexibilide (17), dihydroflexibilide (18), and the enantiomer of 14-deoxycrassin (19). Their structures were determined on the basis of extensive spectroscopic (IR, MS, 2D NMR) data analysis and by comparison with spectroscopic data reported in the literature. Sinulaflexiolides D and E showed selective inhibitory activity against the gastric gland carcinoma cell line BGC-823 at 8.5 and 0.12 μM, respectively." @default.
- W2082422182 created "2016-06-24" @default.
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- W2082422182 date "2008-06-14" @default.
- W2082422182 modified "2023-09-26" @default.
- W2082422182 title "Sinulaflexiolides A−K, Cembrane-Type Diterpenoids from the Chinese Soft Coral <i>Sinularia flexibilis</i>" @default.
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- W2082422182 doi "https://doi.org/10.1021/np070640g" @default.
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