FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082431946> ?p ?o ?g. }

• W2082431946 endingPage "650" @default.
• W2082431946 startingPage "636" @default.
• W2082431946 abstract "Summary Maternal deprivation [24 h on postnatal day 9] might represent an animal model of schizophrenia and behavioural and neurochemical alterations observed in adulthood may be mediated by hippocampal impairments induced by abnormally increased glucocorticoids due to neonatal stress. We aimed to provide new data for psychoimmunoendocrine characterization of this animal model by evaluating its effects in adolescent rats of both genders. In previous studies we found that cannabinoid compounds counteracted the enhanced impulsivity of maternally deprived animals and that the cannabinoid receptor agonist WIN 55,212-2 showed neuroprotective properties in neonatal rats. So, we hypothesised that this compound could counteract at least some of the detrimental effects that we expected to find in maternally deprived animals. Accordingly, the drug was administered immediately after the maternal deprivation period. Maternally deprived males showed significantly decreased motor activity in the holeboard and the plus-maze. The cannabinoid agonist induced, exclusively in males, a significant anxiogenic-like effect, which was reversed by maternal deprivation. In the forced swimming test, both treatments independently induced depressive-like responses. Maternal deprivation reduced immunological function whereas the drug exerted tissue-dependent effects on the immune parameters analysed. Maternally deprived females showed reduced corticosterone levels whereas the cannabinoid agonist increased hormone concentration in all groups. In general, the results show detrimental effects of both treatments as well as intriguing interactions, notably in relation to emotional behaviour and certain immunological responses." @default.
• W2082431946 created "2016-06-24" @default.
• W2082431946 creator A5021863361 @default.
• W2082431946 creator A5021894107 @default.
• W2082431946 creator A5024294784 @default.
• W2082431946 creator A5034905417 @default.
• W2082431946 creator A5063424030 @default.
• W2082431946 creator A5064712625 @default.
• W2082431946 creator A5072439115 @default.
• W2082431946 creator A5076873552 @default.
• W2082431946 date "2007-07-01" @default.
• W2082431946 modified "2023-10-01" @default.
• W2082431946 title "Early maternal deprivation and neonatal single administration with a cannabinoid agonist induce long-term sex-dependent psychoimmunoendocrine effects in adolescent rats" @default.
• W2082431946 cites W136925398 @default.
• W2082431946 cites W1516266278 @default.
• W2082431946 cites W1836729582 @default.
• W2082431946 cites W1964433068 @default.
• W2082431946 cites W1965833191 @default.
• W2082431946 cites W1965948488 @default.
• W2082431946 cites W1973202963 @default.
• W2082431946 cites W1975682905 @default.
• W2082431946 cites W1979742071 @default.
• W2082431946 cites W1985645068 @default.
• W2082431946 cites W1990432673 @default.
• W2082431946 cites W1990499895 @default.
• W2082431946 cites W1992786359 @default.
• W2082431946 cites W1995362640 @default.
• W2082431946 cites W1998915372 @default.
• W2082431946 cites W1999303525 @default.
• W2082431946 cites W2003084130 @default.
• W2082431946 cites W2003640068 @default.
• W2082431946 cites W2003893098 @default.
• W2082431946 cites W2005191203 @default.
• W2082431946 cites W2006802036 @default.
• W2082431946 cites W2008470260 @default.
• W2082431946 cites W2013499279 @default.
• W2082431946 cites W2018167750 @default.
• W2082431946 cites W2019613846 @default.
• W2082431946 cites W2025437677 @default.
• W2082431946 cites W2027465045 @default.
• W2082431946 cites W2030597357 @default.
• W2082431946 cites W2032888359 @default.
• W2082431946 cites W2039598436 @default.
• W2082431946 cites W2041561931 @default.
• W2082431946 cites W2042060537 @default.
• W2082431946 cites W2049950745 @default.
• W2082431946 cites W2050367922 @default.
• W2082431946 cites W2050766410 @default.
• W2082431946 cites W2051761307 @default.
• W2082431946 cites W2052435478 @default.
• W2082431946 cites W2055432435 @default.
• W2082431946 cites W2056891327 @default.
• W2082431946 cites W2059256029 @default.
• W2082431946 cites W2060569726 @default.
• W2082431946 cites W2062682953 @default.
• W2082431946 cites W2065048311 @default.
• W2082431946 cites W2066805539 @default.
• W2082431946 cites W2067768679 @default.
• W2082431946 cites W2068693996 @default.
• W2082431946 cites W2072705021 @default.
• W2082431946 cites W2073047972 @default.
• W2082431946 cites W2075171154 @default.
• W2082431946 cites W2077269414 @default.
• W2082431946 cites W2079745118 @default.
• W2082431946 cites W2080409680 @default.
• W2082431946 cites W2080761118 @default.
• W2082431946 cites W2082376482 @default.
• W2082431946 cites W2088441213 @default.
• W2082431946 cites W2089002543 @default.
• W2082431946 cites W2094081564 @default.
• W2082431946 cites W2094585505 @default.
• W2082431946 cites W2099228076 @default.
• W2082431946 cites W2104586148 @default.
• W2082431946 cites W2107817435 @default.
• W2082431946 cites W2108654808 @default.
• W2082431946 cites W2109177979 @default.
• W2082431946 cites W2112572641 @default.
• W2082431946 cites W2130638685 @default.
• W2082431946 cites W2131478967 @default.
• W2082431946 cites W2136669639 @default.
• W2082431946 cites W2136906274 @default.
• W2082431946 cites W2137360338 @default.
• W2082431946 cites W2144251434 @default.
• W2082431946 cites W2146904199 @default.
• W2082431946 cites W2149907201 @default.
• W2082431946 cites W2154782790 @default.
• W2082431946 cites W2155218627 @default.
• W2082431946 cites W2156019215 @default.
• W2082431946 cites W2157780018 @default.
• W2082431946 cites W2164553936 @default.
• W2082431946 cites W2168516165 @default.
• W2082431946 cites W2171512984 @default.
• W2082431946 cites W27790234 @default.
• W2082431946 doi "https://doi.org/10.1016/j.psyneuen.2007.04.002" @default.
• W2082431946 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17553622" @default.
• W2082431946 hasPublicationYear "2007" @default.
• W2082431946 type Work @default.
• W2082431946 sameAs 2082431946 @default.

• next