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• W2082476368 abstract "ABSTRACT Previous studies have suggested that lipoteichoic acid biosynthesis inhibition is the mechanism of action of daptomycin. In this investigation, daptomycin inhibited all macromolecular synthesis in Staphylococcus aureus , Enterococcus faecalis , and Enterococcus hirae without kinetic or dose specificity for lipoteichoic acid. Daptomycin remained bactericidal in the absence of ongoing lipoteichoic acid synthesis. Inhibition of lipoteichoic acid synthesis is apparently not the mechanism of action of daptomycin in these pathogens." @default.
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• W2082476368 date "2003-08-01" @default.
• W2082476368 modified "2023-10-13" @default.
• W2082476368 title "In Vitro Bactericidal Activities of Daptomycin against <i>Staphylococcus aureus</i> and <i>Enterococcus faecalis</i> Are Not Mediated by Inhibition of Lipoteichoic Acid Biosynthesis" @default.
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• W2082476368 doi "https://doi.org/10.1128/aac.47.8.2682-2684.2003" @default.
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