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- W2082488770 abstract "Objective: To compare serum creatine kinase (CK) values in patients with ectopic pregnancy vs patients with threatened miscarriage or normal pregnancy. Methods: An observational case-control study was performed at an urban teaching hospital. Pregnant women with a quantitative β-hCG obtained for suspicion of ectopic pregnancy were evaluated. Excluded were cases with recent trauma, IM injections, surgery, or history of heart, liver, or muscle disease. The serum β-hCG and CK values were recorded and compared between groups with 1-way ANOVA and Tukey's multiple comparison procedure at the overall 0.05 level. Results: The 15 ectopic, 28 threatened miscarriage, and 21 normal pregnancy cases were of similar gestational ages (p = 0.2), ranging from 3 to 12 weeks. Although the CK values for ectopic pregnancy (88.8 ± 33.6 IU/L) exceeded those for threatened miscarriage (65.9 ± 59.0 IU/L) and normal pregnancy (56.0 ± 38.1 U/L) (p = 0.02), there was significant overlap between groups. CK values were at or above a cutoff of 74 IU/L in 80% (95% confidence interval: 52–96%) of ectopic pregnancies, 25% (11–45%) of threatened miscarriages, and 14% (3–36%) of normal pregnancies. Conclusions: Although the ectopic pregnancy population is characterized by a higher mean CK than are patients with threatened miscarriage or a normal pregnancy, a significant overlap in CK values makes use of this serum marker unreliable for detecting ectopic pregnancy." @default.
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- W2082488770 date "1998-04-01" @default.
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- W2082488770 title "Serum Creatine Kinase Is an Unreliable Predictor of Ectopic Pregnancy" @default.
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- W2082488770 doi "https://doi.org/10.1111/j.1553-2712.1998.tb02708.x" @default.
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