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- W2082493627 abstract "Objectives: There is almost no information regarding the vitamin C status of patients treated in Canadian and American hospitals. We determined the prevalence and predictors of vitamin C deficiency in patients hospitalized on the acute-care wards of a Canadian teaching hospital, and tracked their plasma vitamin C concentrations while they were there.Methods: This was a population-based cross-sectional and time course survey of 149 medical patients shortly after admission to a university teaching hospital. The procedure for sample handling, storage and analysis was validated by measuring the vitamin C concentrations of a reference sample of 141 presumably well nourished people and comparing the results with published norms.Results: In keeping with published norms, 13% of people in the reference group had a subnormal vitamin C concentration (<28.4 μmol/L) and 3% were vitamin C deficient (<11.4 μmol/L). By contrast, 60% of hospitalized patients had a subnormal vitamin C concentration and 19% were deficient. A history of inadequate nutrition or failure to use a vitamin supplement prior to admission, low serum albumin, and male sex predicted plasma vitamin C deficiency, whereas use of a vitamin supplement prior to admission was associated with adequate vitamin C status in hospital. In a second measurement, obtained in 52 patients after an average of 17 days in hospital, vitamin C status had not improved.Conclusions: Vitamin C deficiency is prevalent and sustained in patients in a Canadian teaching hospital. The abnormality can be prevented by providing a diet sufficient in vitamin C or by prescribing a multiple vitamin tablet." @default.
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- W2082493627 date "2008-06-01" @default.
- W2082493627 modified "2023-09-25" @default.
- W2082493627 title "Vitamin C Deficiency in a University Teaching Hospital" @default.
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- W2082493627 doi "https://doi.org/10.1080/07315724.2008.10719721" @default.
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