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- W2082550072 abstract "Abstract Objectives Overactive bladder (OAB) is a pathology impairing patients’ quality of life and with a high percentage of patients who are refractory to medication. In this paper, technical opinion of an «expert panel» is assessed in order to gain the most reliable professional consensus on scientific evidence available on the criteria for the use of Onabotulinumtoxin A (OnabotA) in OAB. Material and methods According to DELPHI method, 42 panelists answered a survey of 93 items divided into four strategic areas including clinical criteria and recommendations in order to improve, at different levels, the current approach to patients with OAB. The recent advances in the field, areas of controversy and their real application possibilities in the different areas of our health care system were taken into consideration. Results Two rounds of the questionnaire were completed by all experts. In the first round, a criteria consensus was reached for 64 of 93 (68.8%) questions analyzed; in the second round the consensus reached was for 83 items evaluated (89.25%). An agreement among panelists was reached for: (1) definition, classification, detection and differential diagnosis; (2) medical treatment; (3) surgical treatment; and (4) role of OnabotA in the treatment of OAB. Conclusions The consensus is broadly in line with the latest scientific evidence on OAB. The panelists believe that it is necessary to propose a change in the current definition of OAB and that it seems necessary to improve the screening tools too. Medical treatment of OAB must be tailored to each patient, staged and progressive. The use of OnabotA (Botox ® ) could imply therapeutic advantages with respect to other treatments, and positions itself as a safe and effective alternative to treat drug refractory OAB." @default.
- W2082550072 created "2016-06-24" @default.
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- W2082550072 date "2014-05-01" @default.
- W2082550072 modified "2023-10-16" @default.
- W2082550072 title "Expert consensus on scientific evidence available on the use of botulinum toxin in overactive bladder" @default.
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- W2082550072 doi "https://doi.org/10.1016/j.acuroe.2014.02.010" @default.
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