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• W2082614528 endingPage "1051" @default.
• W2082614528 startingPage "1049" @default.
• W2082614528 abstract "Feline immunodeficiency virus (FIV)-infected cells have been shown to undergo apoptosis by treatment with tumor necrosis factor alpha (TNF-α). This study detected a soluble factor which enhanced the apoptosis induced by TNF-α treatment. The sensitivity to TNF-α in the induction of apoptosis in a feline fibroblastoid cell line (CRFK) cells was significantly enhanced when the culture supernatant of FIV-infected CRFK cells or plasma samples from FIV-infected cats was added to the culture. These findings suggested that FIV infection induces production of a soluble factor which enhances CRFK cells sensitivity to TNF-α induction of apoptosis both in vitro and in vivo. This factor may contribute to the loss of lymphocytes in cats infected with FIV." @default.
• W2082614528 created "2016-06-24" @default.
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• W2082614528 date "1997-01-01" @default.
• W2082614528 modified "2023-10-17" @default.
• W2082614528 title "Apoptosis Enhanced by Soluble Factor Produced in Feline Immunodeficiency Virus Infection." @default.
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• W2082614528 doi "https://doi.org/10.1292/jvms.59.1049" @default.
• W2082614528 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9409524" @default.
• W2082614528 hasPublicationYear "1997" @default.
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