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- W2082649101 abstract "Abstract The phenomenon, so clearly described in experimental animals, has been seen but rarely in man. A study of this phenomenon in has been made from the review and follow-up of the eleven cases previously reported in the literature and from recent observations upon three individuals who exhibited this phenomenon. This condition, when it occurs, usually involves individuals who have had diabetes mellitus for a considerable time. It is caused usually by infarction of the anterior lobe of the pituitary gland. One of the first effects of the anterior pituitary insufficiency is hypoglycemia. It follows within twenty-four hours after the infarction occurs. In these individuals the hypoglycemia is manifested by bizarre and rapidly changing neurologic signs associated with unconsciousness. These individuals exhibit extreme sensitivity to administered insulin. Those surviving the acute phases of this illness began within a month or two to exhibit the clinical manifestations of deficiencies of thyroid, adrenal and gonadal hormones. Diabetes in these individuals is by no means cured but only ameliorated for the diabetic tendency remains, although the symptoms of diabetes disappear, glycosuria decreases and the level of sugar in the blood approaches the normal level. The response to the stress of intravenously administered glucose is still diabetic in type. Continued administration of insulin to these individuals is sometimes required but the Houssay man is quite as sensitive to insulin as the Houssay dog, and hypoglycemia is always a threat to life." @default.
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- W2082649101 date "1955-09-01" @default.
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- W2082649101 title "The Houssay phenomenon in man" @default.
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- W2082649101 doi "https://doi.org/10.1016/0002-9343(55)90121-2" @default.
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