FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082657714> ?p ?o ?g. }

• W2082657714 endingPage "914.e2" @default.
• W2082657714 startingPage "908" @default.
• W2082657714 abstract "Objective To evaluate the frequency and the natural history of potential (serology positive/Marsh 0-1 histology) celiac disease (CD) in children with a family risk of CD and factors associated with potential instead of overt (serology positive/Marsh 2-3 histology) CD expression. Study design Two-year follow-up study of 96 children (57 females; mean age: 29 ± 12 months) prospectively investigated from birth with: (1) a CD-affected first-degree relative; (2) positivity of serum IgA anti-tissue transglutaminase (tTG) or IgG antigliadin and IgA deficiency; and (3) the results of small intestinal biopsy. Children with potential CD were advised to remain on a gluten containing diet, repeat the celiac antibodies every 6 months, and to have an intestinal biopsy performed in case of persistently high anti-tTG level. Factors discriminating between potential and overt CD were analyzed by decision tree analysis based on the C4.5 algorithm. Results Twenty-four children had potential and 72 overt CD. The stronger predictors of potential CD were lack of symptoms, anti-tTG level lower than 11-fold the upper normal limit, age lower than 24 months, and breastfeeding longer than 8 months. Eighteen out of 21 (86%) patients with potential CD continuing a gluten-containing diet became antibody negative, 1/21 (5%) developed overt CD, and 2/21 (9%) had fluctuating antibodies levels after 2 years. Conclusions The prevalence of potential CD and the percentage of short-term loss of CD-related-antibodies are high in infants at-family-risk for CD. In symptomless children with a positive celiac serology, the decision of performing an intestinal biopsy should be preceded by a period of repeated serological testing. To evaluate the frequency and the natural history of potential (serology positive/Marsh 0-1 histology) celiac disease (CD) in children with a family risk of CD and factors associated with potential instead of overt (serology positive/Marsh 2-3 histology) CD expression. Two-year follow-up study of 96 children (57 females; mean age: 29 ± 12 months) prospectively investigated from birth with: (1) a CD-affected first-degree relative; (2) positivity of serum IgA anti-tissue transglutaminase (tTG) or IgG antigliadin and IgA deficiency; and (3) the results of small intestinal biopsy. Children with potential CD were advised to remain on a gluten containing diet, repeat the celiac antibodies every 6 months, and to have an intestinal biopsy performed in case of persistently high anti-tTG level. Factors discriminating between potential and overt CD were analyzed by decision tree analysis based on the C4.5 algorithm. Twenty-four children had potential and 72 overt CD. The stronger predictors of potential CD were lack of symptoms, anti-tTG level lower than 11-fold the upper normal limit, age lower than 24 months, and breastfeeding longer than 8 months. Eighteen out of 21 (86%) patients with potential CD continuing a gluten-containing diet became antibody negative, 1/21 (5%) developed overt CD, and 2/21 (9%) had fluctuating antibodies levels after 2 years. The prevalence of potential CD and the percentage of short-term loss of CD-related-antibodies are high in infants at-family-risk for CD. In symptomless children with a positive celiac serology, the decision of performing an intestinal biopsy should be preceded by a period of repeated serological testing." @default.
• W2082657714 created "2016-06-24" @default.
• W2082657714 creator A5020165539 @default.
• W2082657714 creator A5046930712 @default.
• W2082657714 creator A5057023049 @default.
• W2082657714 creator A5057481978 @default.
• W2082657714 creator A5065943107 @default.
• W2082657714 creator A5071162889 @default.
• W2082657714 creator A5073688582 @default.
• W2082657714 date "2012-11-01" @default.
• W2082657714 modified "2023-09-29" @default.
• W2082657714 title "Prevalence and Natural History of Potential Celiac Disease in At-Family-Risk Infants Prospectively Investigated from Birth" @default.
• W2082657714 cites W1592644639 @default.
• W2082657714 cites W1899913413 @default.
• W2082657714 cites W1927567833 @default.
• W2082657714 cites W1969319967 @default.
• W2082657714 cites W1978091982 @default.
• W2082657714 cites W1979439493 @default.
• W2082657714 cites W1991398091 @default.
• W2082657714 cites W2002865435 @default.
• W2082657714 cites W2033664948 @default.
• W2082657714 cites W2036798664 @default.
• W2082657714 cites W2041789252 @default.
• W2082657714 cites W2042740864 @default.
• W2082657714 cites W2050647893 @default.
• W2082657714 cites W2054367484 @default.
• W2082657714 cites W2065057152 @default.
• W2082657714 cites W2078462317 @default.
• W2082657714 cites W2100548379 @default.
• W2082657714 cites W2118173032 @default.
• W2082657714 cites W2132565526 @default.
• W2082657714 cites W2134138036 @default.
• W2082657714 cites W2134450123 @default.
• W2082657714 cites W2134686606 @default.
• W2082657714 cites W2137674259 @default.
• W2082657714 cites W2141753151 @default.
• W2082657714 cites W2332372698 @default.
• W2082657714 cites W2911964244 @default.
• W2082657714 cites W4210972014 @default.
• W2082657714 cites W4236137412 @default.
• W2082657714 doi "https://doi.org/10.1016/j.jpeds.2012.05.008" @default.
• W2082657714 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22704250" @default.
• W2082657714 hasPublicationYear "2012" @default.
• W2082657714 type Work @default.
• W2082657714 sameAs 2082657714 @default.
• W2082657714 citedByCount "56" @default.
• W2082657714 countsByYear W20826577142013 @default.
• W2082657714 countsByYear W20826577142014 @default.
• W2082657714 countsByYear W20826577142015 @default.
• W2082657714 countsByYear W20826577142016 @default.
• W2082657714 countsByYear W20826577142017 @default.
• W2082657714 countsByYear W20826577142018 @default.
• W2082657714 countsByYear W20826577142019 @default.
• W2082657714 countsByYear W20826577142020 @default.
• W2082657714 countsByYear W20826577142021 @default.
• W2082657714 countsByYear W20826577142022 @default.
• W2082657714 countsByYear W20826577142023 @default.
• W2082657714 crossrefType "journal-article" @default.
• W2082657714 hasAuthorship W2082657714A5020165539 @default.
• W2082657714 hasAuthorship W2082657714A5046930712 @default.
• W2082657714 hasAuthorship W2082657714A5057023049 @default.
• W2082657714 hasAuthorship W2082657714A5057481978 @default.
• W2082657714 hasAuthorship W2082657714A5065943107 @default.
• W2082657714 hasAuthorship W2082657714A5071162889 @default.
• W2082657714 hasAuthorship W2082657714A5073688582 @default.
• W2082657714 hasConcept C126322002 @default.
• W2082657714 hasConcept C159654299 @default.
• W2082657714 hasConcept C178498320 @default.
• W2082657714 hasConcept C181199279 @default.
• W2082657714 hasConcept C185592680 @default.
• W2082657714 hasConcept C187212893 @default.
• W2082657714 hasConcept C188816634 @default.
• W2082657714 hasConcept C203014093 @default.
• W2082657714 hasConcept C2775934546 @default.
• W2082657714 hasConcept C2776283161 @default.
• W2082657714 hasConcept C2779134260 @default.
• W2082657714 hasConcept C2781179581 @default.
• W2082657714 hasConcept C45189115 @default.
• W2082657714 hasConcept C55493867 @default.
• W2082657714 hasConcept C71924100 @default.
• W2082657714 hasConcept C90924648 @default.
• W2082657714 hasConceptScore W2082657714C126322002 @default.
• W2082657714 hasConceptScore W2082657714C159654299 @default.
• W2082657714 hasConceptScore W2082657714C178498320 @default.
• W2082657714 hasConceptScore W2082657714C181199279 @default.
• W2082657714 hasConceptScore W2082657714C185592680 @default.
• W2082657714 hasConceptScore W2082657714C187212893 @default.
• W2082657714 hasConceptScore W2082657714C188816634 @default.
• W2082657714 hasConceptScore W2082657714C203014093 @default.
• W2082657714 hasConceptScore W2082657714C2775934546 @default.
• W2082657714 hasConceptScore W2082657714C2776283161 @default.
• W2082657714 hasConceptScore W2082657714C2779134260 @default.
• W2082657714 hasConceptScore W2082657714C2781179581 @default.
• W2082657714 hasConceptScore W2082657714C45189115 @default.
• W2082657714 hasConceptScore W2082657714C55493867 @default.
• W2082657714 hasConceptScore W2082657714C71924100 @default.
• W2082657714 hasConceptScore W2082657714C90924648 @default.
• W2082657714 hasIssue "5" @default.

• next