FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082663986> ?p ?o ?g. }

• W2082663986 endingPage "1126" @default.
• W2082663986 startingPage "1123" @default.
• W2082663986 abstract "Hydroxyl radical footprinting is a technique for studying protein structure and binding that entails oxidizing a protein system of interest with diffusing hydroxyl radicals, and then measuring the amount of oxidation of each amino acid. One important issue in hydroxyl radical footprinting is limiting amino acid oxidation by secondary oxidants to prevent uncontrolled oxidation, which can cause amino acids to appear more solvent accessible than they really are. Previous work suggested that hydrogen peroxide was the major secondary oxidant of concern in hydroxyl radical footprinting experiments; however, even after elimination of all hydrogen peroxide, some secondary oxidation was still detected. Evidence is presented for the formation of peptidyl hydroperoxides as the most abundant product upon oxidation of aliphatic amino acids. Both reverse phase liquid chromatography and catalase treatment were shown to be ineffective at eliminating peptidyl hydroperoxides. The ability of these peptidyl hydroperoxides to directly oxidize methionine is demonstrated, suggesting the value of methionine amide as an in situ protectant. Hydroxyl radical footprinting protocols require the use of an organic sulfide or similar peroxide scavenger in addition to removal of hydrogen peroxide to successfully eradicate all secondary oxidizing species and prevent uncontrolled oxidation of sulfur-containing residues." @default.
• W2082663986 created "2016-06-24" @default.
• W2082663986 creator A5055980813 @default.
• W2082663986 creator A5056857548 @default.
• W2082663986 creator A5073108061 @default.
• W2082663986 creator A5073127030 @default.
• W2082663986 date "2009-06-01" @default.
• W2082663986 modified "2023-09-25" @default.
• W2082663986 title "Aliphatic peptidyl hydroperoxides as a source of secondary oxidation in hydroxyl radical protein footprinting" @default.
• W2082663986 cites W1702181542 @default.
• W2082663986 cites W1968831035 @default.
• W2082663986 cites W1982986081 @default.
• W2082663986 cites W1986085342 @default.
• W2082663986 cites W1986777063 @default.
• W2082663986 cites W2007912187 @default.
• W2082663986 cites W2024849484 @default.
• W2082663986 cites W2027856108 @default.
• W2082663986 cites W2036384204 @default.
• W2082663986 cites W2046879382 @default.
• W2082663986 cites W2061296264 @default.
• W2082663986 cites W2062184252 @default.
• W2082663986 cites W2079959579 @default.
• W2082663986 cites W2086120012 @default.
• W2082663986 cites W2127143218 @default.
• W2082663986 cites W2127411356 @default.
• W2082663986 cites W2130437872 @default.
• W2082663986 cites W2146686514 @default.
• W2082663986 cites W2163913710 @default.
• W2082663986 doi "https://doi.org/10.1016/j.jasms.2009.02.004" @default.
• W2082663986 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2684652" @default.
• W2082663986 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19278868" @default.
• W2082663986 hasPublicationYear "2009" @default.
• W2082663986 type Work @default.
• W2082663986 sameAs 2082663986 @default.
• W2082663986 citedByCount "36" @default.
• W2082663986 countsByYear W20826639862012 @default.
• W2082663986 countsByYear W20826639862013 @default.
• W2082663986 countsByYear W20826639862014 @default.
• W2082663986 countsByYear W20826639862015 @default.
• W2082663986 countsByYear W20826639862017 @default.
• W2082663986 countsByYear W20826639862018 @default.
• W2082663986 countsByYear W20826639862019 @default.
• W2082663986 countsByYear W20826639862020 @default.
• W2082663986 countsByYear W20826639862021 @default.
• W2082663986 countsByYear W20826639862022 @default.
• W2082663986 countsByYear W20826639862023 @default.
• W2082663986 crossrefType "journal-article" @default.
• W2082663986 hasAuthorship W2082663986A5055980813 @default.
• W2082663986 hasAuthorship W2082663986A5056857548 @default.
• W2082663986 hasAuthorship W2082663986A5073108061 @default.
• W2082663986 hasAuthorship W2082663986A5073127030 @default.
• W2082663986 hasBestOaLocation W20826639861 @default.
• W2082663986 hasConcept C139066938 @default.
• W2082663986 hasConcept C178790620 @default.
• W2082663986 hasConcept C181199279 @default.
• W2082663986 hasConcept C185592680 @default.
• W2082663986 hasConcept C2776778087 @default.
• W2082663986 hasConcept C2776880858 @default.
• W2082663986 hasConcept C2777608289 @default.
• W2082663986 hasConcept C2778021871 @default.
• W2082663986 hasConcept C2779201268 @default.
• W2082663986 hasConcept C2780912031 @default.
• W2082663986 hasConcept C2781048764 @default.
• W2082663986 hasConcept C3017666073 @default.
• W2082663986 hasConcept C515207424 @default.
• W2082663986 hasConcept C533411734 @default.
• W2082663986 hasConcept C552990157 @default.
• W2082663986 hasConcept C55493867 @default.
• W2082663986 hasConcept C77176794 @default.
• W2082663986 hasConceptScore W2082663986C139066938 @default.
• W2082663986 hasConceptScore W2082663986C178790620 @default.
• W2082663986 hasConceptScore W2082663986C181199279 @default.
• W2082663986 hasConceptScore W2082663986C185592680 @default.
• W2082663986 hasConceptScore W2082663986C2776778087 @default.
• W2082663986 hasConceptScore W2082663986C2776880858 @default.
• W2082663986 hasConceptScore W2082663986C2777608289 @default.
• W2082663986 hasConceptScore W2082663986C2778021871 @default.
• W2082663986 hasConceptScore W2082663986C2779201268 @default.
• W2082663986 hasConceptScore W2082663986C2780912031 @default.
• W2082663986 hasConceptScore W2082663986C2781048764 @default.
• W2082663986 hasConceptScore W2082663986C3017666073 @default.
• W2082663986 hasConceptScore W2082663986C515207424 @default.
• W2082663986 hasConceptScore W2082663986C533411734 @default.
• W2082663986 hasConceptScore W2082663986C552990157 @default.
• W2082663986 hasConceptScore W2082663986C55493867 @default.
• W2082663986 hasConceptScore W2082663986C77176794 @default.
• W2082663986 hasIssue "6" @default.
• W2082663986 hasLocation W20826639861 @default.
• W2082663986 hasLocation W20826639862 @default.
• W2082663986 hasLocation W20826639863 @default.
• W2082663986 hasLocation W20826639864 @default.
• W2082663986 hasOpenAccess W2082663986 @default.
• W2082663986 hasPrimaryLocation W20826639861 @default.
• W2082663986 hasRelatedWork W2082663986 @default.
• W2082663986 hasRelatedWork W2142635451 @default.
• W2082663986 hasRelatedWork W2315730682 @default.
• W2082663986 hasRelatedWork W2375797739 @default.
• W2082663986 hasRelatedWork W2396174601 @default.

• next