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• W2082665903 abstract "The application of taurine (2-aminoethanesulfonic acid) induces a long-lasting increase of synaptic efficacy and axon excitability (LLP-TAU) in rat hippocampal CA1 area. After taurine withdrawal, LLP-TAU lasted at least 3 h. This fact prompted us to assess whether the mechanisms involved in the maintenance of this particular potentiation were similar to those implicated in the late phase of long-term potentiation (L-LTP). In the presence of KN-62, an inhibitor of calcium/calmodulin-dependent protein kinase, taurine perfusion (10 mM, 30 min) did not affect the induction of LLP-TAU. However, LLP-TAU maintenance was completely suppressed by KT5720, an inhibitor of the cAMP-dependent protein kinase (PKA). Moreover, the late phase of LLP-TAU was blocked by inhibiting protein synthesis with anisomycin. In addition, taurine perfusion increased the phosphorylation of cAMP response element-binding protein (CREB), although did not affect cAMP levels. These features of LLP-TAU do not appear to be caused by the activation of D1/D5 dopamine receptors, as taurine also induced synaptic potentiation in the presence of SCH23390, an antagonist of this type of receptors. Finally, the late phase of both L-LTP and LLP-TAU occluded mutually. These results suggest that taurine triggers the sequence of some of the molecular events involved in the induction of L-LTP." @default.
• W2082665903 created "2016-06-24" @default.
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• W2082665903 date "2003-01-01" @default.
• W2082665903 modified "2023-09-30" @default.
• W2082665903 title "Taurine-induced synaptic potentiation and the late phase of long-term potentiation are related mechanistically" @default.
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• W2082665903 cites W1564467813 @default.
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• W2082665903 cites W164492255 @default.
• W2082665903 cites W1670445830 @default.
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• W2082665903 cites W1783929995 @default.
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• W2082665903 cites W1998247213 @default.
• W2082665903 cites W1999488417 @default.
• W2082665903 cites W2002927748 @default.
• W2082665903 cites W2008792865 @default.
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• W2082665903 doi "https://doi.org/10.1016/s0028-3908(02)00310-6" @default.
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