FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082710928> ?p ?o ?g. }

• W2082710928 endingPage "246" @default.
• W2082710928 startingPage "238" @default.
• W2082710928 abstract "Our objective was to explore interest in genetic testing among Ashkenazi Jewish (AJ) Parkinson's Disease (PD) cases and first-degree relatives, as genetic testing for LRRK2 G2019S is widely available. Approximately 18 % of AJ PD cases carry G2019S mutations; penetrance estimations vary between 24 and 100 % by age 80. A Genetic Attitude Questionnaire (GAQ) was administered at two New York sites to PD families unaware of LRRK2 G2019S mutation status. The association of G2019S, age, education, gender and family history of PD with desire for genetic testing (outcome) was modeled using logistic regression. One-hundred eleven PD cases and 77 relatives completed the GAQ. Both PD cases and relatives had excellent PD-specific genetic knowledge. Among PD, 32.6 % definitely and 41.1 % probably wanted testing, if offered now. Among relatives, 23.6 % definitely and 36.1 % probably wanted testing now. Desire for testing in relatives increased incrementally based on hypothetical risk of PD. The most important reasons for testing in probands and relatives were: if it influenced medication response, identifying no mutation, and early prevention and treatment. In logistic regression, older age was associated with less desire for testing in probands OR = 0.921 95%CI 0.868-0.977, p = 0.009. Both probands and relatives express interest in genetic testing, despite no link to current treatment or prevention." @default.
• W2082710928 created "2016-06-24" @default.
• W2082710928 creator A5004301111 @default.
• W2082710928 creator A5004865231 @default.
• W2082710928 creator A5015080716 @default.
• W2082710928 creator A5019194582 @default.
• W2082710928 creator A5019215184 @default.
• W2082710928 creator A5024118424 @default.
• W2082710928 creator A5028125302 @default.
• W2082710928 creator A5037098776 @default.
• W2082710928 creator A5039274182 @default.
• W2082710928 creator A5039384247 @default.
• W2082710928 creator A5044072989 @default.
• W2082710928 creator A5056393710 @default.
• W2082710928 creator A5070888101 @default.
• W2082710928 creator A5071249832 @default.
• W2082710928 creator A5083090238 @default.
• W2082710928 date "2014-08-17" @default.
• W2082710928 modified "2023-10-14" @default.
• W2082710928 title "Interest in Genetic Testing in Ashkenazi Jewish Parkinson’s Disease Patients and Their Unaffected Relatives" @default.
• W2082710928 cites W1558427337 @default.
• W2082710928 cites W1966745703 @default.
• W2082710928 cites W1977261578 @default.
• W2082710928 cites W2001666948 @default.
• W2082710928 cites W2008560062 @default.
• W2082710928 cites W2008886854 @default.
• W2082710928 cites W2021842029 @default.
• W2082710928 cites W2052135081 @default.
• W2082710928 cites W2055246234 @default.
• W2082710928 cites W2068351933 @default.
• W2082710928 cites W2076319039 @default.
• W2082710928 cites W2097983832 @default.
• W2082710928 cites W2109691114 @default.
• W2082710928 cites W2116877425 @default.
• W2082710928 cites W2170281382 @default.
• W2082710928 cites W2328105863 @default.
• W2082710928 doi "https://doi.org/10.1007/s10897-014-9756-x" @default.
• W2082710928 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4331260" @default.
• W2082710928 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25127731" @default.
• W2082710928 hasPublicationYear "2014" @default.
• W2082710928 type Work @default.
• W2082710928 sameAs 2082710928 @default.
• W2082710928 citedByCount "23" @default.
• W2082710928 countsByYear W20827109282015 @default.
• W2082710928 countsByYear W20827109282017 @default.
• W2082710928 countsByYear W20827109282018 @default.
• W2082710928 countsByYear W20827109282019 @default.
• W2082710928 countsByYear W20827109282020 @default.
• W2082710928 countsByYear W20827109282021 @default.
• W2082710928 countsByYear W20827109282022 @default.
• W2082710928 countsByYear W20827109282023 @default.
• W2082710928 crossrefType "journal-article" @default.
• W2082710928 hasAuthorship W2082710928A5004301111 @default.
• W2082710928 hasAuthorship W2082710928A5004865231 @default.
• W2082710928 hasAuthorship W2082710928A5015080716 @default.
• W2082710928 hasAuthorship W2082710928A5019194582 @default.
• W2082710928 hasAuthorship W2082710928A5019215184 @default.
• W2082710928 hasAuthorship W2082710928A5024118424 @default.
• W2082710928 hasAuthorship W2082710928A5028125302 @default.
• W2082710928 hasAuthorship W2082710928A5037098776 @default.
• W2082710928 hasAuthorship W2082710928A5039274182 @default.
• W2082710928 hasAuthorship W2082710928A5039384247 @default.
• W2082710928 hasAuthorship W2082710928A5044072989 @default.
• W2082710928 hasAuthorship W2082710928A5056393710 @default.
• W2082710928 hasAuthorship W2082710928A5070888101 @default.
• W2082710928 hasAuthorship W2082710928A5071249832 @default.
• W2082710928 hasAuthorship W2082710928A5083090238 @default.
• W2082710928 hasBestOaLocation W20827109282 @default.
• W2082710928 hasConcept C104317684 @default.
• W2082710928 hasConcept C126322002 @default.
• W2082710928 hasConcept C127716648 @default.
• W2082710928 hasConcept C144024400 @default.
• W2082710928 hasConcept C149923435 @default.
• W2082710928 hasConcept C151956035 @default.
• W2082710928 hasConcept C188997412 @default.
• W2082710928 hasConcept C200544954 @default.
• W2082710928 hasConcept C2779134260 @default.
• W2082710928 hasConcept C2780673598 @default.
• W2082710928 hasConcept C2781179581 @default.
• W2082710928 hasConcept C501734568 @default.
• W2082710928 hasConcept C512399662 @default.
• W2082710928 hasConcept C54355233 @default.
• W2082710928 hasConcept C71924100 @default.
• W2082710928 hasConcept C80227256 @default.
• W2082710928 hasConcept C86803240 @default.
• W2082710928 hasConceptScore W2082710928C104317684 @default.
• W2082710928 hasConceptScore W2082710928C126322002 @default.
• W2082710928 hasConceptScore W2082710928C127716648 @default.
• W2082710928 hasConceptScore W2082710928C144024400 @default.
• W2082710928 hasConceptScore W2082710928C149923435 @default.
• W2082710928 hasConceptScore W2082710928C151956035 @default.
• W2082710928 hasConceptScore W2082710928C188997412 @default.
• W2082710928 hasConceptScore W2082710928C200544954 @default.
• W2082710928 hasConceptScore W2082710928C2779134260 @default.
• W2082710928 hasConceptScore W2082710928C2780673598 @default.
• W2082710928 hasConceptScore W2082710928C2781179581 @default.
• W2082710928 hasConceptScore W2082710928C501734568 @default.
• W2082710928 hasConceptScore W2082710928C512399662 @default.

• next