Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082736531> ?p ?o ?g. }
- W2082736531 endingPage "862" @default.
- W2082736531 startingPage "862" @default.
- W2082736531 abstract "The full-length cDNA of genomic segment A of three infectious bursal disease viruses, two attenuated strains (HZ2 and JD1) and one virulent field strain (ZJ2000), was amplified in a single step by reverse transcription-polymerase chain reaction, cloned into pGEM-T Easy Vector, and sequenced. The full length of cloned segment A contains 3259 nucleotides, which includes two partially overlapping open reading fragments (ORFs) ORF1 and ORF2, flanked by 5' and 3' noncoding regions. These strains shared high sequence identity with each other either at the nucleotide or deduced amino acid level. Strains HZ2 and JD1 were highly related to two attenuated strains, CEF94 and P2, whereas ZJ2000 was closely related to two other virulent strains, Cu-1 and Harbin. Substitutions of four amino acids at positions 253, 279, 284, and 330, a common feature of attenuated and most virulent strains, were also observed in these three strains. Two major hydrophilic peaks were conserved in the three strains; however, there are two amino acid substitutions at positions 280 (N to S) and 290 (M to L) in the second minor hydrophilic peak for all three strains, which might have a critical influence on antigenicity. Two amino acid substitutions near the VP2-VP4 cleavage site were identified in virulent strain JZ2000, which might be involved in increasing the virulence of the virus. Phylogenetic analyses indicated that these three Chinese strains are most closely related to some European virulent strains but are distinct from very virulent infectious bursal disease virus and variant strains." @default.
- W2082736531 created "2016-06-24" @default.
- W2082736531 creator A5023511950 @default.
- W2082736531 creator A5031687035 @default.
- W2082736531 creator A5053411772 @default.
- W2082736531 creator A5053489307 @default.
- W2082736531 creator A5084515803 @default.
- W2082736531 date "2001-10-01" @default.
- W2082736531 modified "2023-09-25" @default.
- W2082736531 title "Molecular Characteristics of Full-Length Genomic Segment A of Three Infectious Bursal Disease Viruses in China: Two Attenuated Strains and One Virulent Field Strain" @default.
- W2082736531 cites W1510193986 @default.
- W2082736531 cites W1953426278 @default.
- W2082736531 cites W1974417513 @default.
- W2082736531 cites W1974975419 @default.
- W2082736531 cites W1979399804 @default.
- W2082736531 cites W1981170346 @default.
- W2082736531 cites W2019602944 @default.
- W2082736531 cites W2022402960 @default.
- W2082736531 cites W2025093374 @default.
- W2082736531 cites W2026042432 @default.
- W2082736531 cites W2035803121 @default.
- W2082736531 cites W2038268657 @default.
- W2082736531 cites W2043915120 @default.
- W2082736531 cites W2054773709 @default.
- W2082736531 cites W2073919042 @default.
- W2082736531 cites W2078360808 @default.
- W2082736531 cites W2078388202 @default.
- W2082736531 cites W2080685033 @default.
- W2082736531 cites W2083699981 @default.
- W2082736531 cites W2086015895 @default.
- W2082736531 cites W2088944980 @default.
- W2082736531 cites W2107187291 @default.
- W2082736531 cites W2126238955 @default.
- W2082736531 cites W2131822013 @default.
- W2082736531 cites W2136467008 @default.
- W2082736531 cites W2137320144 @default.
- W2082736531 cites W2140798543 @default.
- W2082736531 cites W2141604717 @default.
- W2082736531 cites W2144679271 @default.
- W2082736531 cites W2148080468 @default.
- W2082736531 cites W2148394257 @default.
- W2082736531 cites W2169263563 @default.
- W2082736531 cites W2182575874 @default.
- W2082736531 cites W2189131273 @default.
- W2082736531 cites W2314026963 @default.
- W2082736531 cites W2314529641 @default.
- W2082736531 cites W2324521453 @default.
- W2082736531 cites W2326508225 @default.
- W2082736531 cites W2382094162 @default.
- W2082736531 cites W2391467791 @default.
- W2082736531 cites W3148135790 @default.
- W2082736531 doi "https://doi.org/10.2307/1592866" @default.
- W2082736531 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11785891" @default.
- W2082736531 hasPublicationYear "2001" @default.
- W2082736531 type Work @default.
- W2082736531 sameAs 2082736531 @default.
- W2082736531 citedByCount "16" @default.
- W2082736531 countsByYear W20827365312017 @default.
- W2082736531 countsByYear W20827365312018 @default.
- W2082736531 countsByYear W20827365312023 @default.
- W2082736531 crossrefType "journal-article" @default.
- W2082736531 hasAuthorship W2082736531A5023511950 @default.
- W2082736531 hasAuthorship W2082736531A5031687035 @default.
- W2082736531 hasAuthorship W2082736531A5053411772 @default.
- W2082736531 hasAuthorship W2082736531A5053489307 @default.
- W2082736531 hasAuthorship W2082736531A5084515803 @default.
- W2082736531 hasConcept C104317684 @default.
- W2082736531 hasConcept C147483822 @default.
- W2082736531 hasConcept C159047783 @default.
- W2082736531 hasConcept C167625842 @default.
- W2082736531 hasConcept C187882448 @default.
- W2082736531 hasConcept C2777810641 @default.
- W2082736531 hasConcept C2779026604 @default.
- W2082736531 hasConcept C2780530800 @default.
- W2082736531 hasConcept C47289529 @default.
- W2082736531 hasConcept C54355233 @default.
- W2082736531 hasConcept C54602769 @default.
- W2082736531 hasConcept C60987743 @default.
- W2082736531 hasConcept C84148353 @default.
- W2082736531 hasConcept C86803240 @default.
- W2082736531 hasConceptScore W2082736531C104317684 @default.
- W2082736531 hasConceptScore W2082736531C147483822 @default.
- W2082736531 hasConceptScore W2082736531C159047783 @default.
- W2082736531 hasConceptScore W2082736531C167625842 @default.
- W2082736531 hasConceptScore W2082736531C187882448 @default.
- W2082736531 hasConceptScore W2082736531C2777810641 @default.
- W2082736531 hasConceptScore W2082736531C2779026604 @default.
- W2082736531 hasConceptScore W2082736531C2780530800 @default.
- W2082736531 hasConceptScore W2082736531C47289529 @default.
- W2082736531 hasConceptScore W2082736531C54355233 @default.
- W2082736531 hasConceptScore W2082736531C54602769 @default.
- W2082736531 hasConceptScore W2082736531C60987743 @default.
- W2082736531 hasConceptScore W2082736531C84148353 @default.
- W2082736531 hasConceptScore W2082736531C86803240 @default.
- W2082736531 hasIssue "4" @default.
- W2082736531 hasLocation W20827365311 @default.
- W2082736531 hasLocation W20827365312 @default.
- W2082736531 hasOpenAccess W2082736531 @default.