Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082742611> ?p ?o ?g. }
- W2082742611 endingPage "297" @default.
- W2082742611 startingPage "292" @default.
- W2082742611 abstract "Belamcanda chinensis (Iridaceae) belongs to the family of iridaceae and its rhizoma has been widely used for the treatment of throat ailment. Here we report a new pharmacological activity of B. chinensis leaf extract (BCL), that is, the hypoglycemic effect in normal and STZ-induced diabetic rats. Animals either healthy or STZ-induced diabetic show significantly lowered fasting blood glucose levels after treatment with BCL. The serum insulin concentration in normal rats is also enhanced. Additionally, the increase in blood glucose levels after administration of various carbohydrates in normal rats is significantly decreased and the oral glucose tolerance (OGTT) of STZ-induced diabetic rats is largely improved by BCL treatment. However, co-administration of BCL with Nifedipine, a Ca2+ ion channel blocker, or Nicorandil, an ATP-sensitive K+ ion channel opener thoroughly abolishes the hypoglycemic effect of BCL. HPLC analysis and compound identification showed that several isoflavone glycosides with antidiabetic activities were contained in BCL while pharmacological experiment showed that the polysaccharide fraction of BCL had no significant hypoglycemic effect on normal rats. Therefore, the isoflavone glycosides but not polysaccharides might be the active fraction of BCL in diabetes treatment." @default.
- W2082742611 created "2016-06-24" @default.
- W2082742611 creator A5014957211 @default.
- W2082742611 creator A5027361910 @default.
- W2082742611 creator A5030400389 @default.
- W2082742611 creator A5037045029 @default.
- W2082742611 creator A5047535866 @default.
- W2082742611 creator A5056120792 @default.
- W2082742611 creator A5057272360 @default.
- W2082742611 creator A5077251679 @default.
- W2082742611 date "2011-02-01" @default.
- W2082742611 modified "2023-09-22" @default.
- W2082742611 title "Hypoglycemic effect of Belamcanda chinensis leaf extract in normal and STZ-induced diabetic rats and its potential active faction" @default.
- W2082742611 cites W1964616422 @default.
- W2082742611 cites W1964858438 @default.
- W2082742611 cites W1965220528 @default.
- W2082742611 cites W1968788297 @default.
- W2082742611 cites W1981153465 @default.
- W2082742611 cites W1981711957 @default.
- W2082742611 cites W1985156905 @default.
- W2082742611 cites W1999846963 @default.
- W2082742611 cites W2035609051 @default.
- W2082742611 cites W2036047122 @default.
- W2082742611 cites W2037029585 @default.
- W2082742611 cites W2052598014 @default.
- W2082742611 cites W2056526409 @default.
- W2082742611 cites W2061744220 @default.
- W2082742611 cites W2062384175 @default.
- W2082742611 cites W2064731429 @default.
- W2082742611 cites W2089863969 @default.
- W2082742611 cites W2092087913 @default.
- W2082742611 cites W2104214122 @default.
- W2082742611 cites W2111117284 @default.
- W2082742611 cites W2120704605 @default.
- W2082742611 cites W2124828030 @default.
- W2082742611 cites W2127062749 @default.
- W2082742611 cites W2138975391 @default.
- W2082742611 cites W2167665257 @default.
- W2082742611 cites W2253896940 @default.
- W2082742611 cites W2407236892 @default.
- W2082742611 doi "https://doi.org/10.1016/j.phymed.2010.07.005" @default.
- W2082742611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20739161" @default.
- W2082742611 hasPublicationYear "2011" @default.
- W2082742611 type Work @default.
- W2082742611 sameAs 2082742611 @default.
- W2082742611 citedByCount "46" @default.
- W2082742611 countsByYear W20827426112012 @default.
- W2082742611 countsByYear W20827426112013 @default.
- W2082742611 countsByYear W20827426112014 @default.
- W2082742611 countsByYear W20827426112015 @default.
- W2082742611 countsByYear W20827426112016 @default.
- W2082742611 countsByYear W20827426112017 @default.
- W2082742611 countsByYear W20827426112018 @default.
- W2082742611 countsByYear W20827426112019 @default.
- W2082742611 countsByYear W20827426112020 @default.
- W2082742611 countsByYear W20827426112021 @default.
- W2082742611 countsByYear W20827426112022 @default.
- W2082742611 countsByYear W20827426112023 @default.
- W2082742611 crossrefType "journal-article" @default.
- W2082742611 hasAuthorship W2082742611A5014957211 @default.
- W2082742611 hasAuthorship W2082742611A5027361910 @default.
- W2082742611 hasAuthorship W2082742611A5030400389 @default.
- W2082742611 hasAuthorship W2082742611A5037045029 @default.
- W2082742611 hasAuthorship W2082742611A5047535866 @default.
- W2082742611 hasAuthorship W2082742611A5056120792 @default.
- W2082742611 hasAuthorship W2082742611A5057272360 @default.
- W2082742611 hasAuthorship W2082742611A5077251679 @default.
- W2082742611 hasConcept C100817775 @default.
- W2082742611 hasConcept C126322002 @default.
- W2082742611 hasConcept C134018914 @default.
- W2082742611 hasConcept C142724271 @default.
- W2082742611 hasConcept C178790620 @default.
- W2082742611 hasConcept C185592680 @default.
- W2082742611 hasConcept C194671627 @default.
- W2082742611 hasConcept C204787440 @default.
- W2082742611 hasConcept C2777056448 @default.
- W2082742611 hasConcept C2778902376 @default.
- W2082742611 hasConcept C2779306644 @default.
- W2082742611 hasConcept C2779626144 @default.
- W2082742611 hasConcept C55493867 @default.
- W2082742611 hasConcept C555293320 @default.
- W2082742611 hasConcept C556039675 @default.
- W2082742611 hasConcept C71924100 @default.
- W2082742611 hasConcept C98274493 @default.
- W2082742611 hasConceptScore W2082742611C100817775 @default.
- W2082742611 hasConceptScore W2082742611C126322002 @default.
- W2082742611 hasConceptScore W2082742611C134018914 @default.
- W2082742611 hasConceptScore W2082742611C142724271 @default.
- W2082742611 hasConceptScore W2082742611C178790620 @default.
- W2082742611 hasConceptScore W2082742611C185592680 @default.
- W2082742611 hasConceptScore W2082742611C194671627 @default.
- W2082742611 hasConceptScore W2082742611C204787440 @default.
- W2082742611 hasConceptScore W2082742611C2777056448 @default.
- W2082742611 hasConceptScore W2082742611C2778902376 @default.
- W2082742611 hasConceptScore W2082742611C2779306644 @default.
- W2082742611 hasConceptScore W2082742611C2779626144 @default.
- W2082742611 hasConceptScore W2082742611C55493867 @default.
- W2082742611 hasConceptScore W2082742611C555293320 @default.