FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082756709> ?p ?o ?g. }

• W2082756709 endingPage "289" @default.
• W2082756709 startingPage "280" @default.
• W2082756709 abstract "Several herpesviruses induce expression of the selectin receptor sialyl-Lewis X (sLex) by activating transcription of one or more of silent host FUT genes, each one encoding a fucosyltransferase that catalyses the rate-limiting step of sLex synthesis. The aim here was to identify the identity of the glycoconjugate associated with sLex glycoepitope in herpes simplex virus type 1 (HSV-1) infected human diploid fibroblasts, using immunofluorescence confocal microscopy. Cells infected with all tested HSV-1 strains analysed demonstrated bright sLex fluorescence, except for two mutant viruses that were unable to induce proper expression of viral glycoprotein gC-1: One gC-1 null mutant and another mutant expressing gC-1 devoid of its major O-glycan-containing region (aa 33–116). The sLex reactivity of HSV-1 infected cells was abolished by mild alkali treatment. Altogether the results indicated that the detectable sLex was associated with O-linked glycans, situated in the mucin region of gC-1. No evidence for sLex (i) in other HSV-1 glycoproteins with mucin domains such as gI-1 or (ii) in host cell glycoproteins/glycolipids was found. Thus, the mucin domain of HSV-1 gC-1 may support expression of selectin ligands such as sLex and other larger O-linked glycans in cell types lacking endogenous mucin domain-containing glycoproteins, optimized for O-glycan expression, provided that the adequate host glycosyltransferase genes are activated." @default.
• W2082756709 created "2016-06-24" @default.
• W2082756709 creator A5006951133 @default.
• W2082756709 creator A5011340804 @default.
• W2082756709 creator A5016189480 @default.
• W2082756709 creator A5022316371 @default.
• W2082756709 creator A5035772207 @default.
• W2082756709 creator A5049912825 @default.
• W2082756709 creator A5051346408 @default.
• W2082756709 creator A5078801352 @default.
• W2082756709 date "2012-09-07" @default.
• W2082756709 modified "2023-09-25" @default.
• W2082756709 title "Involvement of viral glycoprotein gC-1 in expression of the selectin ligand sialyl-Lewis X induced after infection with herpes simplex virus type 1" @default.
• W2082756709 cites W1514619790 @default.
• W2082756709 cites W1546590751 @default.
• W2082756709 cites W1552707981 @default.
• W2082756709 cites W162468362 @default.
• W2082756709 cites W1867634595 @default.
• W2082756709 cites W1971801922 @default.
• W2082756709 cites W1974056920 @default.
• W2082756709 cites W1987111733 @default.
• W2082756709 cites W1994049232 @default.
• W2082756709 cites W2017614262 @default.
• W2082756709 cites W2018991730 @default.
• W2082756709 cites W2035809865 @default.
• W2082756709 cites W2040363612 @default.
• W2082756709 cites W2041740280 @default.
• W2082756709 cites W2044545721 @default.
• W2082756709 cites W2072969560 @default.
• W2082756709 cites W2077753375 @default.
• W2082756709 cites W2083217959 @default.
• W2082756709 cites W2091016446 @default.
• W2082756709 cites W2096533439 @default.
• W2082756709 cites W2096765666 @default.
• W2082756709 cites W2103522627 @default.
• W2082756709 cites W2106585168 @default.
• W2082756709 cites W2106604059 @default.
• W2082756709 cites W2109139112 @default.
• W2082756709 cites W2117946498 @default.
• W2082756709 cites W2138709084 @default.
• W2082756709 cites W2142738561 @default.
• W2082756709 cites W2145097136 @default.
• W2082756709 cites W2166720212 @default.
• W2082756709 cites W2171685333 @default.
• W2082756709 cites W2184766456 @default.
• W2082756709 cites W4297000720 @default.
• W2082756709 doi "https://doi.org/10.1111/j.1600-0463.2012.02967.x" @default.
• W2082756709 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23030500" @default.
• W2082756709 hasPublicationYear "2012" @default.
• W2082756709 type Work @default.
• W2082756709 sameAs 2082756709 @default.
• W2082756709 citedByCount "9" @default.
• W2082756709 countsByYear W20827567092014 @default.
• W2082756709 countsByYear W20827567092015 @default.
• W2082756709 countsByYear W20827567092016 @default.
• W2082756709 countsByYear W20827567092018 @default.
• W2082756709 countsByYear W20827567092020 @default.
• W2082756709 countsByYear W20827567092021 @default.
• W2082756709 countsByYear W20827567092022 @default.
• W2082756709 crossrefType "journal-article" @default.
• W2082756709 hasAuthorship W2082756709A5006951133 @default.
• W2082756709 hasAuthorship W2082756709A5011340804 @default.
• W2082756709 hasAuthorship W2082756709A5016189480 @default.
• W2082756709 hasAuthorship W2082756709A5022316371 @default.
• W2082756709 hasAuthorship W2082756709A5035772207 @default.
• W2082756709 hasAuthorship W2082756709A5049912825 @default.
• W2082756709 hasAuthorship W2082756709A5051346408 @default.
• W2082756709 hasAuthorship W2082756709A5078801352 @default.
• W2082756709 hasConcept C104317684 @default.
• W2082756709 hasConcept C108625454 @default.
• W2082756709 hasConcept C143065580 @default.
• W2082756709 hasConcept C153911025 @default.
• W2082756709 hasConcept C155619193 @default.
• W2082756709 hasConcept C159047783 @default.
• W2082756709 hasConcept C16224149 @default.
• W2082756709 hasConcept C179264091 @default.
• W2082756709 hasConcept C185592680 @default.
• W2082756709 hasConcept C206212055 @default.
• W2082756709 hasConcept C22222904 @default.
• W2082756709 hasConcept C2522874641 @default.
• W2082756709 hasConcept C2777117008 @default.
• W2082756709 hasConcept C2777762822 @default.
• W2082756709 hasConcept C2779212266 @default.
• W2082756709 hasConcept C2781196997 @default.
• W2082756709 hasConcept C55493867 @default.
• W2082756709 hasConcept C86803240 @default.
• W2082756709 hasConcept C95444343 @default.
• W2082756709 hasConceptScore W2082756709C104317684 @default.
• W2082756709 hasConceptScore W2082756709C108625454 @default.
• W2082756709 hasConceptScore W2082756709C143065580 @default.
• W2082756709 hasConceptScore W2082756709C153911025 @default.
• W2082756709 hasConceptScore W2082756709C155619193 @default.
• W2082756709 hasConceptScore W2082756709C159047783 @default.
• W2082756709 hasConceptScore W2082756709C16224149 @default.
• W2082756709 hasConceptScore W2082756709C179264091 @default.
• W2082756709 hasConceptScore W2082756709C185592680 @default.
• W2082756709 hasConceptScore W2082756709C206212055 @default.
• W2082756709 hasConceptScore W2082756709C22222904 @default.

• next