FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082781045> ?p ?o ?g. }

• W2082781045 endingPage "304" @default.
• W2082781045 startingPage "287" @default.
• W2082781045 abstract "Following a primary bovine herpesvlrus-1 (BHV-1) infection the concanavalln A (Con A) induced proliferative responses of peripheral blood T lymphocytes were suppressed. This suppression occurred in the absence of detectible serum suppressor factors, suppressor cell activity or decreased accessory cell function. However, regression analysis demonstrated a significant correlation between the percentage of T lymphocytes present within the peripheral blood mononuclear cell (PBMC) population and the amplitude of Con-A-induced lymphocyte proliferative responses (LPR). Direct evidence that a numerical deficit of responder T lymphocytes was limiting LPR was obtained by using an immunomagnetic microsphere (IMM) negative enrichment protocol to produce a PBMC population with a constant percentage (75 ± 6%) of T lymphocytes. The Con-A-induced LPR of these enriched T lymphocytes remained constant following BHV-1 infection. Flow cytometric (FC) analysis of PBMC indicated that the decreased percentage of circulating T lymphocytes, associated with BHV-1 infection, was caused primarily by a selective depletion of the BoT8 subset. These FC data were consistent with the indirect evidence of increased TH activity, as indicated by elevated Con A-induced IL-2 production. Thus, 2 to 5 days following viral infection, the circulating T lymphocytes were activated as shown by elevated IL-2 production, increased recombinant bovine IL-2 (rBoIL-2)-induced LPR, and elevated levels of cellular 2′-5′ A synthetase activity. The significance of the selective depletion of a lymphocyte subpopulation and immune activation following a primary BHV-1 infection is discussed." @default.
• W2082781045 created "2016-06-24" @default.
• W2082781045 creator A5009968414 @default.
• W2082781045 creator A5039088246 @default.
• W2082781045 creator A5047258184 @default.
• W2082781045 creator A5053235127 @default.
• W2082781045 creator A5058966859 @default.
• W2082781045 creator A5079330921 @default.
• W2082781045 creator A5082754214 @default.
• W2082781045 date "1987-01-01" @default.
• W2082781045 modified "2023-09-23" @default.
• W2082781045 title "T Lymphocyte Population Dynamics and Function Following a Primary Bovine Herpesvirus Type-1 Infection" @default.
• W2082781045 cites W1510734092 @default.
• W2082781045 cites W1545686401 @default.
• W2082781045 cites W1555319444 @default.
• W2082781045 cites W1569141376 @default.
• W2082781045 cites W1583955786 @default.
• W2082781045 cites W1860178574 @default.
• W2082781045 cites W1916947918 @default.
• W2082781045 cites W2022937128 @default.
• W2082781045 cites W2023706105 @default.
• W2082781045 cites W2028408293 @default.
• W2082781045 cites W2038758352 @default.
• W2082781045 cites W2055275614 @default.
• W2082781045 cites W2056026795 @default.
• W2082781045 cites W2062256867 @default.
• W2082781045 cites W2070491195 @default.
• W2082781045 cites W2079525639 @default.
• W2082781045 cites W2111653919 @default.
• W2082781045 cites W2112770600 @default.
• W2082781045 cites W2112923458 @default.
• W2082781045 doi "https://doi.org/10.1089/vim.1987.1.287" @default.
• W2082781045 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3509949" @default.
• W2082781045 hasPublicationYear "1987" @default.
• W2082781045 type Work @default.
• W2082781045 sameAs 2082781045 @default.
• W2082781045 citedByCount "66" @default.
• W2082781045 countsByYear W20827810452012 @default.
• W2082781045 countsByYear W20827810452013 @default.
• W2082781045 countsByYear W20827810452014 @default.
• W2082781045 countsByYear W20827810452016 @default.
• W2082781045 countsByYear W20827810452018 @default.
• W2082781045 countsByYear W20827810452019 @default.
• W2082781045 countsByYear W20827810452021 @default.
• W2082781045 countsByYear W20827810452023 @default.
• W2082781045 crossrefType "journal-article" @default.
• W2082781045 hasAuthorship W2082781045A5009968414 @default.
• W2082781045 hasAuthorship W2082781045A5039088246 @default.
• W2082781045 hasAuthorship W2082781045A5047258184 @default.
• W2082781045 hasAuthorship W2082781045A5053235127 @default.
• W2082781045 hasAuthorship W2082781045A5058966859 @default.
• W2082781045 hasAuthorship W2082781045A5079330921 @default.
• W2082781045 hasAuthorship W2082781045A5082754214 @default.
• W2082781045 hasConcept C137061746 @default.
• W2082781045 hasConcept C153911025 @default.
• W2082781045 hasConcept C202751555 @default.
• W2082781045 hasConcept C203014093 @default.
• W2082781045 hasConcept C2776090121 @default.
• W2082781045 hasConcept C2777761686 @default.
• W2082781045 hasConcept C2908647359 @default.
• W2082781045 hasConcept C2992881475 @default.
• W2082781045 hasConcept C55493867 @default.
• W2082781045 hasConcept C71924100 @default.
• W2082781045 hasConcept C86803240 @default.
• W2082781045 hasConcept C8891405 @default.
• W2082781045 hasConcept C99454951 @default.
• W2082781045 hasConceptScore W2082781045C137061746 @default.
• W2082781045 hasConceptScore W2082781045C153911025 @default.
• W2082781045 hasConceptScore W2082781045C202751555 @default.
• W2082781045 hasConceptScore W2082781045C203014093 @default.
• W2082781045 hasConceptScore W2082781045C2776090121 @default.
• W2082781045 hasConceptScore W2082781045C2777761686 @default.
• W2082781045 hasConceptScore W2082781045C2908647359 @default.
• W2082781045 hasConceptScore W2082781045C2992881475 @default.
• W2082781045 hasConceptScore W2082781045C55493867 @default.
• W2082781045 hasConceptScore W2082781045C71924100 @default.
• W2082781045 hasConceptScore W2082781045C86803240 @default.
• W2082781045 hasConceptScore W2082781045C8891405 @default.
• W2082781045 hasConceptScore W2082781045C99454951 @default.
• W2082781045 hasIssue "4" @default.
• W2082781045 hasLocation W20827810451 @default.
• W2082781045 hasLocation W20827810452 @default.
• W2082781045 hasOpenAccess W2082781045 @default.
• W2082781045 hasPrimaryLocation W20827810451 @default.
• W2082781045 hasRelatedWork W1506984959 @default.
• W2082781045 hasRelatedWork W1975729558 @default.
• W2082781045 hasRelatedWork W2001994960 @default.
• W2082781045 hasRelatedWork W2003613721 @default.
• W2082781045 hasRelatedWork W2056385328 @default.
• W2082781045 hasRelatedWork W2104268645 @default.
• W2082781045 hasRelatedWork W2149871822 @default.
• W2082781045 hasRelatedWork W2350954440 @default.
• W2082781045 hasRelatedWork W2402307906 @default.
• W2082781045 hasRelatedWork W91868852 @default.
• W2082781045 hasVolume "1" @default.
• W2082781045 isParatext "false" @default.
• W2082781045 isRetracted "false" @default.
• W2082781045 magId "2082781045" @default.

• next