FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082851306> ?p ?o ?g. }

• W2082851306 endingPage "67" @default.
• W2082851306 startingPage "59" @default.
• W2082851306 abstract "In recent years, the concept of cancer chemoprevention has matured greatly. Significant reversal or suppression of premalignancy in several sites by chemopreventive agents appears achievable. This article summarizes experimental data on chemopreventive effects of tea polyphenols in different tumor bioassay systems. Tea (Camellia sinensis) is cultivated in about 30 countries, and is the most widely consumed beverage in the world. Three main commercial tea varieties--green, black, and oolong--are usually consumed, but most experimental studies demonstrating the antimutagenic and anticarcinogenic effects of tea have been conducted with water extract of green tea, or a polyphenolic fraction isolated from green tea (GTP). The majority of these studies have been conducted in a mouse skin tumor model system where tea is fed either as water extract through drinking water, or as purified GTP. GTP has been shown to exhibit antimutagenic activity in vitro, and inhibit carcinogen- as well as UV-induced skin carcinogenesis in vivo. Tea consumption has also been shown to afford protection against chemical carcinogen-induced stomach, lung, esophagus, duodenum, pancreas, liver, breast, and colon carcinogenesis in specific bioassay models. Several epicatechin derivatives (polyphenols) present in green tea have been shown to possess anticarcinogenic activity; the most active is (-)-epigallocatechin-3-gallate, which is also the major constituent of GTP. The mechanisms of tea's broad cancer chemopreventive effects are not completely understood. Several theories have been put forward, including inhibition of UV- and tumor promoter-induced ornithine decarboxylase, cyclo-oxygenase, and lipoxygenase activities, antioxidant and free radical scavenging activity; enhancement of antioxidant (glutathione peroxidase, catalase, and quinone reductase) and phase II (glutathione-S-transferase) enzyme activities; inhibition of lipid peroxidation, and anti-inflammatory activity. These properties of tea polyphenols make them effective chemopreventive agents against the initiation, promotion, and progression stages of multistage carcinogenesis." @default.
• W2082851306 created "2016-06-24" @default.
• W2082851306 creator A5036743590 @default.
• W2082851306 creator A5082425428 @default.
• W2082851306 date "1997-01-01" @default.
• W2082851306 modified "2023-10-17" @default.
• W2082851306 title "Tea antioxidants in cancer chemoprevention" @default.
• W2082851306 cites W115875504 @default.
• W2082851306 cites W1965211395 @default.
• W2082851306 cites W1967936513 @default.
• W2082851306 cites W1977908472 @default.
• W2082851306 cites W1980429742 @default.
• W2082851306 cites W1980608074 @default.
• W2082851306 cites W1986093516 @default.
• W2082851306 cites W1986635247 @default.
• W2082851306 cites W1987841769 @default.
• W2082851306 cites W1988050165 @default.
• W2082851306 cites W1990961363 @default.
• W2082851306 cites W2010692661 @default.
• W2082851306 cites W2018933707 @default.
• W2082851306 cites W2023504262 @default.
• W2082851306 cites W2024754142 @default.
• W2082851306 cites W2026398700 @default.
• W2082851306 cites W2028091438 @default.
• W2082851306 cites W2031377838 @default.
• W2082851306 cites W2038143172 @default.
• W2082851306 cites W2039249065 @default.
• W2082851306 cites W2047324474 @default.
• W2082851306 cites W2051620527 @default.
• W2082851306 cites W2054999245 @default.
• W2082851306 cites W2056576522 @default.
• W2082851306 cites W2058905454 @default.
• W2082851306 cites W2066196838 @default.
• W2082851306 cites W2074605208 @default.
• W2082851306 cites W2075480222 @default.
• W2082851306 cites W2078760421 @default.
• W2082851306 cites W2081505189 @default.
• W2082851306 cites W2084995559 @default.
• W2082851306 cites W2095046939 @default.
• W2082851306 cites W2117894833 @default.
• W2082851306 cites W2124690619 @default.
• W2082851306 cites W2330569962 @default.
• W2082851306 cites W2614442853 @default.
• W2082851306 cites W306138507 @default.
• W2082851306 doi "https://doi.org/10.1002/(sici)1097-4644(1997)27+<59::aid-jcb11>3.0.co;2-g" @default.
• W2082851306 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9591194" @default.
• W2082851306 hasPublicationYear "1997" @default.
• W2082851306 type Work @default.
• W2082851306 sameAs 2082851306 @default.
• W2082851306 citedByCount "187" @default.
• W2082851306 countsByYear W20828513062012 @default.
• W2082851306 countsByYear W20828513062013 @default.
• W2082851306 countsByYear W20828513062014 @default.
• W2082851306 countsByYear W20828513062015 @default.
• W2082851306 countsByYear W20828513062016 @default.
• W2082851306 countsByYear W20828513062017 @default.
• W2082851306 countsByYear W20828513062018 @default.
• W2082851306 countsByYear W20828513062019 @default.
• W2082851306 countsByYear W20828513062020 @default.
• W2082851306 countsByYear W20828513062021 @default.
• W2082851306 countsByYear W20828513062023 @default.
• W2082851306 crossrefType "journal-article" @default.
• W2082851306 hasAuthorship W2082851306A5036743590 @default.
• W2082851306 hasAuthorship W2082851306A5082425428 @default.
• W2082851306 hasConcept C104317684 @default.
• W2082851306 hasConcept C104488531 @default.
• W2082851306 hasConcept C114246631 @default.
• W2082851306 hasConcept C185592680 @default.
• W2082851306 hasConcept C2777192995 @default.
• W2082851306 hasConcept C2777787921 @default.
• W2082851306 hasConcept C2778004101 @default.
• W2082851306 hasConcept C2779107934 @default.
• W2082851306 hasConcept C2992816389 @default.
• W2082851306 hasConcept C31903555 @default.
• W2082851306 hasConcept C54355233 @default.
• W2082851306 hasConcept C55493867 @default.
• W2082851306 hasConcept C555283112 @default.
• W2082851306 hasConcept C59822182 @default.
• W2082851306 hasConcept C70899900 @default.
• W2082851306 hasConcept C86803240 @default.
• W2082851306 hasConcept C98274493 @default.
• W2082851306 hasConceptScore W2082851306C104317684 @default.
• W2082851306 hasConceptScore W2082851306C104488531 @default.
• W2082851306 hasConceptScore W2082851306C114246631 @default.
• W2082851306 hasConceptScore W2082851306C185592680 @default.
• W2082851306 hasConceptScore W2082851306C2777192995 @default.
• W2082851306 hasConceptScore W2082851306C2777787921 @default.
• W2082851306 hasConceptScore W2082851306C2778004101 @default.
• W2082851306 hasConceptScore W2082851306C2779107934 @default.
• W2082851306 hasConceptScore W2082851306C2992816389 @default.
• W2082851306 hasConceptScore W2082851306C31903555 @default.
• W2082851306 hasConceptScore W2082851306C54355233 @default.
• W2082851306 hasConceptScore W2082851306C55493867 @default.
• W2082851306 hasConceptScore W2082851306C555283112 @default.
• W2082851306 hasConceptScore W2082851306C59822182 @default.
• W2082851306 hasConceptScore W2082851306C70899900 @default.
• W2082851306 hasConceptScore W2082851306C86803240 @default.
• W2082851306 hasConceptScore W2082851306C98274493 @default.

• next