FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082859532> ?p ?o ?g. }

• W2082859532 abstract "The world health organization (WHO) declared tuberculosis (TB) a global emergency, mainly affecting people in sub-Saharan Africa. However there is little data about the burden of TB among adolescents. We estimated the prevalence and incidence of TB and assessed factors associated with TB among adolescents aged 12–18 years in a rural population in Uganda in order to prepare the site for phase III clinical trials with novel TB vaccines among adolescents. In a prospective cohort study, we recruited 5000 adolescents and followed them actively, every 6 months, for 1–2 years. Participants suspected of having TB were those who had any of; TB signs and symptoms, history of TB contact or a positive tuberculin skin test (TST) of ≥10 mm. Laboratory investigations included sputum smear microscopy and culture. Of the 5000 participants, eight culture confirmed cases of TB were found at baseline: a prevalence of 160/100,000 (95% confidence interval (CI), 69–315). There were 13 incident TB cases detected in an average of 1.1 person years: an incidence of 235/100,000 person years (95% CI, 125–402). None of the confirmed TB cases were HIV infected. Predictors for prevalent TB disease were: a history of TB contact and a cough ≥ 2 weeks at baseline and being out of school, while the only predictor for incident TB was a positive TST during follow-up. The TB incidence among adolescents in this rural part of Uganda seemed too low for a phase III TB vaccine trial. However, the study site demonstrated capability to handle a large number of participants with minimal loss to follow-up and its suitability for future clinical trials. Improved contact tracing in TB program activities is likely to increase TB case detection among adolescents. Future studies should explore possible pockets of higher TB incidence in urban areas and among out of school youth." @default.
• W2082859532 created "2016-06-24" @default.
• W2082859532 creator A5016138987 @default.
• W2082859532 creator A5033846551 @default.
• W2082859532 creator A5046080862 @default.
• W2082859532 creator A5047224141 @default.
• W2082859532 creator A5050125317 @default.
• W2082859532 creator A5057946567 @default.
• W2082859532 creator A5069420215 @default.
• W2082859532 creator A5074967283 @default.
• W2082859532 date "2013-07-26" @default.
• W2082859532 modified "2023-10-09" @default.
• W2082859532 title "Burden of tuberculosis disease among adolescents in a rural cohort in Eastern Uganda" @default.
• W2082859532 cites W2032274680 @default.
• W2082859532 cites W2056855833 @default.
• W2082859532 cites W2066191478 @default.
• W2082859532 cites W2106682613 @default.
• W2082859532 cites W2116331185 @default.
• W2082859532 cites W2138203188 @default.
• W2082859532 cites W2146710904 @default.
• W2082859532 cites W2148298144 @default.
• W2082859532 cites W2152283349 @default.
• W2082859532 cites W2170536158 @default.
• W2082859532 cites W4240883132 @default.
• W2082859532 doi "https://doi.org/10.1186/1471-2334-13-349" @default.
• W2082859532 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3735406" @default.
• W2082859532 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23890464" @default.
• W2082859532 hasPublicationYear "2013" @default.
• W2082859532 type Work @default.
• W2082859532 sameAs 2082859532 @default.
• W2082859532 citedByCount "18" @default.
• W2082859532 countsByYear W20828595322015 @default.
• W2082859532 countsByYear W20828595322016 @default.
• W2082859532 countsByYear W20828595322017 @default.
• W2082859532 countsByYear W20828595322018 @default.
• W2082859532 countsByYear W20828595322019 @default.
• W2082859532 countsByYear W20828595322020 @default.
• W2082859532 countsByYear W20828595322021 @default.
• W2082859532 countsByYear W20828595322022 @default.
• W2082859532 countsByYear W20828595322023 @default.
• W2082859532 crossrefType "journal-article" @default.
• W2082859532 hasAuthorship W2082859532A5016138987 @default.
• W2082859532 hasAuthorship W2082859532A5033846551 @default.
• W2082859532 hasAuthorship W2082859532A5046080862 @default.
• W2082859532 hasAuthorship W2082859532A5047224141 @default.
• W2082859532 hasAuthorship W2082859532A5050125317 @default.
• W2082859532 hasAuthorship W2082859532A5057946567 @default.
• W2082859532 hasAuthorship W2082859532A5069420215 @default.
• W2082859532 hasAuthorship W2082859532A5074967283 @default.
• W2082859532 hasBestOaLocation W20828595321 @default.
• W2082859532 hasConcept C113162765 @default.
• W2082859532 hasConcept C120665830 @default.
• W2082859532 hasConcept C121332964 @default.
• W2082859532 hasConcept C126322002 @default.
• W2082859532 hasConcept C142724271 @default.
• W2082859532 hasConcept C185032368 @default.
• W2082859532 hasConcept C187212893 @default.
• W2082859532 hasConcept C188816634 @default.
• W2082859532 hasConcept C190139176 @default.
• W2082859532 hasConcept C201903717 @default.
• W2082859532 hasConcept C203014093 @default.
• W2082859532 hasConcept C2776247216 @default.
• W2082859532 hasConcept C2776301714 @default.
• W2082859532 hasConcept C2779134260 @default.
• W2082859532 hasConcept C2781069245 @default.
• W2082859532 hasConcept C2908647359 @default.
• W2082859532 hasConcept C3008058167 @default.
• W2082859532 hasConcept C524204448 @default.
• W2082859532 hasConcept C61511704 @default.
• W2082859532 hasConcept C71924100 @default.
• W2082859532 hasConcept C72563966 @default.
• W2082859532 hasConcept C99454951 @default.
• W2082859532 hasConceptScore W2082859532C113162765 @default.
• W2082859532 hasConceptScore W2082859532C120665830 @default.
• W2082859532 hasConceptScore W2082859532C121332964 @default.
• W2082859532 hasConceptScore W2082859532C126322002 @default.
• W2082859532 hasConceptScore W2082859532C142724271 @default.
• W2082859532 hasConceptScore W2082859532C185032368 @default.
• W2082859532 hasConceptScore W2082859532C187212893 @default.
• W2082859532 hasConceptScore W2082859532C188816634 @default.
• W2082859532 hasConceptScore W2082859532C190139176 @default.
• W2082859532 hasConceptScore W2082859532C201903717 @default.
• W2082859532 hasConceptScore W2082859532C203014093 @default.
• W2082859532 hasConceptScore W2082859532C2776247216 @default.
• W2082859532 hasConceptScore W2082859532C2776301714 @default.
• W2082859532 hasConceptScore W2082859532C2779134260 @default.
• W2082859532 hasConceptScore W2082859532C2781069245 @default.
• W2082859532 hasConceptScore W2082859532C2908647359 @default.
• W2082859532 hasConceptScore W2082859532C3008058167 @default.
• W2082859532 hasConceptScore W2082859532C524204448 @default.
• W2082859532 hasConceptScore W2082859532C61511704 @default.
• W2082859532 hasConceptScore W2082859532C71924100 @default.
• W2082859532 hasConceptScore W2082859532C72563966 @default.
• W2082859532 hasConceptScore W2082859532C99454951 @default.
• W2082859532 hasIssue "1" @default.
• W2082859532 hasLocation W20828595321 @default.
• W2082859532 hasLocation W20828595322 @default.
• W2082859532 hasLocation W20828595323 @default.
• W2082859532 hasLocation W20828595324 @default.
• W2082859532 hasLocation W20828595325 @default.

• next