Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082875761> ?p ?o ?g. }
- W2082875761 abstract "A key feature of many pathogenic microorganisms is the presence of a dense glycocalyx at their surface, composed of lipid-anchored glycoproteins and non-protein-bound polysaccharides. These surface glycolipids are important virulence factors for bacterial, fungal and protozoan pathogens. The highly complex glycoconjugate lipophosphoglycan (LPG) is one of the dominant surface macromolecules of the promastigote stage of all Leishmania parasitic species. LPG plays critical pleiotropic roles in parasite survival and infectivity in both the sandfly vector and the mammalian host. Here, we review the composition of the Leishmania glycocalyx, the chemical structure of LPG and what is currently known about its effects in the mammalian host, specifically. We will then discuss the current approaches employed to elucidate LPG functions. Finally, we will provide a viewpoint on future directions that this area of investigation could take to unravel in detail the biological activity of the specific molecular elements composing the structurally complex LPG." @default.
- W2082875761 created "2016-06-24" @default.
- W2082875761 creator A5006418968 @default.
- W2082875761 creator A5013131547 @default.
- W2082875761 creator A5043809554 @default.
- W2082875761 date "2015-01-21" @default.
- W2082875761 modified "2023-10-13" @default.
- W2082875761 title "Leishmania lipophosphoglycan: how to establish structure-activity relationships for this highly complex and multifunctional glycoconjugate?" @default.
- W2082875761 cites W1482209102 @default.
- W2082875761 cites W1492856261 @default.
- W2082875761 cites W1553079447 @default.
- W2082875761 cites W1872902033 @default.
- W2082875761 cites W1915912984 @default.
- W2082875761 cites W1944304173 @default.
- W2082875761 cites W1971258058 @default.
- W2082875761 cites W1973030143 @default.
- W2082875761 cites W1979736443 @default.
- W2082875761 cites W1983263820 @default.
- W2082875761 cites W1985622878 @default.
- W2082875761 cites W1992837217 @default.
- W2082875761 cites W1994068102 @default.
- W2082875761 cites W2000445336 @default.
- W2082875761 cites W2005547658 @default.
- W2082875761 cites W2013352196 @default.
- W2082875761 cites W2018138443 @default.
- W2082875761 cites W2024396003 @default.
- W2082875761 cites W2035113683 @default.
- W2082875761 cites W2035652756 @default.
- W2082875761 cites W2039070421 @default.
- W2082875761 cites W2040615674 @default.
- W2082875761 cites W2047439639 @default.
- W2082875761 cites W2047630725 @default.
- W2082875761 cites W2047718198 @default.
- W2082875761 cites W2049361955 @default.
- W2082875761 cites W2060087365 @default.
- W2082875761 cites W2066639757 @default.
- W2082875761 cites W2066648696 @default.
- W2082875761 cites W2075034695 @default.
- W2082875761 cites W2078670297 @default.
- W2082875761 cites W2085643898 @default.
- W2082875761 cites W2086157478 @default.
- W2082875761 cites W2087585684 @default.
- W2082875761 cites W2089392449 @default.
- W2082875761 cites W2091421625 @default.
- W2082875761 cites W2097479016 @default.
- W2082875761 cites W2097684886 @default.
- W2082875761 cites W2104475366 @default.
- W2082875761 cites W2113179494 @default.
- W2082875761 cites W2117786106 @default.
- W2082875761 cites W2121284960 @default.
- W2082875761 cites W2123377654 @default.
- W2082875761 cites W2125795592 @default.
- W2082875761 cites W2128903401 @default.
- W2082875761 cites W2129440396 @default.
- W2082875761 cites W2130967505 @default.
- W2082875761 cites W2131986661 @default.
- W2082875761 cites W2132913823 @default.
- W2082875761 cites W2133150386 @default.
- W2082875761 cites W2135554061 @default.
- W2082875761 cites W2136327400 @default.
- W2082875761 cites W2138974828 @default.
- W2082875761 cites W2140250744 @default.
- W2082875761 cites W2142161087 @default.
- W2082875761 cites W2145413858 @default.
- W2082875761 cites W2156580324 @default.
- W2082875761 cites W2164312174 @default.
- W2082875761 cites W2164354626 @default.
- W2082875761 cites W2165138725 @default.
- W2082875761 cites W2165199797 @default.
- W2082875761 cites W2167986691 @default.
- W2082875761 cites W2181304380 @default.
- W2082875761 cites W2242929700 @default.
- W2082875761 doi "https://doi.org/10.3389/fcimb.2014.00193" @default.
- W2082875761 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4301024" @default.
- W2082875761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25653924" @default.
- W2082875761 hasPublicationYear "2015" @default.
- W2082875761 type Work @default.
- W2082875761 sameAs 2082875761 @default.
- W2082875761 citedByCount "52" @default.
- W2082875761 countsByYear W20828757612015 @default.
- W2082875761 countsByYear W20828757612016 @default.
- W2082875761 countsByYear W20828757612017 @default.
- W2082875761 countsByYear W20828757612018 @default.
- W2082875761 countsByYear W20828757612019 @default.
- W2082875761 countsByYear W20828757612020 @default.
- W2082875761 countsByYear W20828757612021 @default.
- W2082875761 countsByYear W20828757612022 @default.
- W2082875761 countsByYear W20828757612023 @default.
- W2082875761 crossrefType "journal-article" @default.
- W2082875761 hasAuthorship W2082875761A5006418968 @default.
- W2082875761 hasAuthorship W2082875761A5013131547 @default.
- W2082875761 hasAuthorship W2082875761A5043809554 @default.
- W2082875761 hasBestOaLocation W20828757611 @default.
- W2082875761 hasConcept C104317684 @default.
- W2082875761 hasConcept C106358424 @default.
- W2082875761 hasConcept C108625454 @default.
- W2082875761 hasConcept C13426554 @default.
- W2082875761 hasConcept C136764020 @default.
- W2082875761 hasConcept C203014093 @default.
- W2082875761 hasConcept C206212055 @default.