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- W2082904682 abstract "A cylindrical shape prototype aerosol inhalation device that was previously shown to enhance pulmonary deposition from a nebulizer was evaluated for its performance in conjunction with a pressurized metered dose inhalation aerosol (MDI). Gammascintigraphic studies in human volunteers using radiolabeled technetium Tc 99m sulfur colloid (TSC) MDI showed this prototype to enhance sulfur colloid deposition in the lungs and minimize oropharyngeal deposition. A second in vivo study conducted with a new compact prototype designed for commercial development showed similar pulmonary deposition profiles with the radiolabeled TSC MDI. Data from these studies with the radiolabeled MDI show that both the prototypes enhanced pulmonary deposition and minimized oropharyngeal deposition in comparison with commercial inhalation devices." @default.
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- W2082904682 date "1996-02-01" @default.
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- W2082904682 title "A novel aerosol inhalation device for pressurized metered dose inhalation aerosols: Gammascintigraphic evaluation of pulmonary deposition profiles and comparison with commercial inhalation devices" @default.
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- W2082904682 doi "https://doi.org/10.1016/0378-5173(95)04219-9" @default.
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