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- W2082939540 abstract "Lipoproteins were isolated by sequential ultracentrifugation, and the concentrations and compositions were determined in nondiabetic (ND), borderline diabetic (BD), and diabetic (D) Macaca nigra males consuming a chow ration. The total concentrations and components of the VLDL and IDL increased significantly with metabolic deterioration (P < 0.01). Concentrations and components of LDL increased in the BD and D monkeys, but changes were not statistically significant. The HDLZ and HDL particles were virtually unchanged among the three different metabolic groups. The VLDL was the major carrier of the triglycerides, especially in D monkeys. Cholesterol was present predominantly in the LDL. The LDL-cholesterol to HDL-cholesterol ratio increased in the BD and D monkeys, owing mainly to increases in the LDL-cholesterol content. Apoprotein antisera showed apoprotein B in the VLDL, IDL, and LDL, apoprotein E in the VLDL and IDL, and apoprotein A-1 in the HDL2 and HDL3 fractions. Because Macaca nigra consume a nonatherogenic, low-cholesterol, low-fat ration, the changes in lipoproteins, particularly in VLDL and IDL, are attributable to metabolic alterations associated with diabetes." @default.
- W2082939540 created "2016-06-24" @default.
- W2082939540 creator A5005611287 @default.
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- W2082939540 date "1987-01-01" @default.
- W2082939540 modified "2023-10-18" @default.
- W2082939540 title "Lipoprotein patterns in nondiabetic, borderline diabetic, and diabetic Macaca nigra" @default.
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- W2082939540 doi "https://doi.org/10.1016/0021-9150(87)90084-0" @default.
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