FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2082995751> ?p ?o ?g. }

• W2082995751 endingPage "244" @default.
• W2082995751 startingPage "233" @default.
• W2082995751 abstract "In a cell-free system the influence of acute aflatoxin B1 administration on the fractions of the hepatic microsomal translation complex of female rats was examined and compared with the influence of chronic aflatoxin B1 treatment. Polypeptide synthesis determined by [14C]leucine incorporation with the postmitochondrial supernatant was inhibited by 80% 24 h after acute aflatoxin B1 administration whereas inhibition was only 17% in animals 30 weeks after chronic treatment. After acute aflatoxin B1 administration inhibition of protein synthesis was by 67%, mainly on the polysomal level, whereas inhibition with the pH 5 enzyme was only by 22%. After chronic aflatoxin B1 administration inhibition was by 18%, mainly with the pH 5 enzyme and by only 6% on the polysomes. The inhibition by pH 5 enzyme was further investigated with regard to aminoacyl-tRNA synthetases, components of pH 5 enzyme. Leucine-specific aminoacyl-tRNA synthesis was inhibited by 20% 24 h after acute and by 12% 30 weeks after chronic aflatoxin B1 treatment. Aminoacyl-tRNA synthetase activities in a crude synthetase preparation tested with 5 amino acids were found to be noncompetitively inhibited. It is concluded that the inhibition of protein synthesis after acute and chronic aflatoxin B1 administration is in part due to decreased aminoacyl-tRNA levels caused by inhibited aminoacyl-tRNA synthetases." @default.
• W2082995751 created "2016-06-24" @default.
• W2082995751 creator A5036949387 @default.
• W2082995751 creator A5066841598 @default.
• W2082995751 date "1981-10-01" @default.
• W2082995751 modified "2023-09-26" @default.
• W2082995751 title "Inhibition of rat liver aminoacyl-tRNA synthetases in vitro after acute and chronic aflatoxin B1 administration in vivo" @default.
• W2082995751 cites W1515940431 @default.
• W2082995751 cites W1775749144 @default.
• W2082995751 cites W1975207834 @default.
• W2082995751 cites W1985281171 @default.
• W2082995751 cites W1988002389 @default.
• W2082995751 cites W1997357069 @default.
• W2082995751 cites W2006282277 @default.
• W2082995751 cites W2010651340 @default.
• W2082995751 cites W2017684491 @default.
• W2082995751 cites W2018408395 @default.
• W2082995751 cites W2025742247 @default.
• W2082995751 cites W2025866652 @default.
• W2082995751 cites W2030999163 @default.
• W2082995751 cites W2053880949 @default.
• W2082995751 cites W2055455091 @default.
• W2082995751 cites W2064950949 @default.
• W2082995751 cites W2070939965 @default.
• W2082995751 cites W2073181437 @default.
• W2082995751 cites W2075688715 @default.
• W2082995751 cites W2107148003 @default.
• W2082995751 cites W2188702955 @default.
• W2082995751 cites W2232394755 @default.
• W2082995751 cites W2304606127 @default.
• W2082995751 cites W256512334 @default.
• W2082995751 doi "https://doi.org/10.1016/0009-2797(81)90180-0" @default.
• W2082995751 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6793252" @default.
• W2082995751 hasPublicationYear "1981" @default.
• W2082995751 type Work @default.
• W2082995751 sameAs 2082995751 @default.
• W2082995751 citedByCount "7" @default.
• W2082995751 countsByYear W20829957512013 @default.
• W2082995751 crossrefType "journal-article" @default.
• W2082995751 hasAuthorship W2082995751A5036949387 @default.
• W2082995751 hasAuthorship W2082995751A5066841598 @default.
• W2082995751 hasConcept C104317684 @default.
• W2082995751 hasConcept C150903083 @default.
• W2082995751 hasConcept C153957851 @default.
• W2082995751 hasConcept C181199279 @default.
• W2082995751 hasConcept C185592680 @default.
• W2082995751 hasConcept C202751555 @default.
• W2082995751 hasConcept C207001950 @default.
• W2082995751 hasConcept C2776580952 @default.
• W2082995751 hasConcept C2779315393 @default.
• W2082995751 hasConcept C28212737 @default.
• W2082995751 hasConcept C31903555 @default.
• W2082995751 hasConcept C3675279 @default.
• W2082995751 hasConcept C40758303 @default.
• W2082995751 hasConcept C515207424 @default.
• W2082995751 hasConcept C55493867 @default.
• W2082995751 hasConcept C67705224 @default.
• W2082995751 hasConcept C86803240 @default.
• W2082995751 hasConcept C87644729 @default.
• W2082995751 hasConcept C98274493 @default.
• W2082995751 hasConceptScore W2082995751C104317684 @default.
• W2082995751 hasConceptScore W2082995751C150903083 @default.
• W2082995751 hasConceptScore W2082995751C153957851 @default.
• W2082995751 hasConceptScore W2082995751C181199279 @default.
• W2082995751 hasConceptScore W2082995751C185592680 @default.
• W2082995751 hasConceptScore W2082995751C202751555 @default.
• W2082995751 hasConceptScore W2082995751C207001950 @default.
• W2082995751 hasConceptScore W2082995751C2776580952 @default.
• W2082995751 hasConceptScore W2082995751C2779315393 @default.
• W2082995751 hasConceptScore W2082995751C28212737 @default.
• W2082995751 hasConceptScore W2082995751C31903555 @default.
• W2082995751 hasConceptScore W2082995751C3675279 @default.
• W2082995751 hasConceptScore W2082995751C40758303 @default.
• W2082995751 hasConceptScore W2082995751C515207424 @default.
• W2082995751 hasConceptScore W2082995751C55493867 @default.
• W2082995751 hasConceptScore W2082995751C67705224 @default.
• W2082995751 hasConceptScore W2082995751C86803240 @default.
• W2082995751 hasConceptScore W2082995751C87644729 @default.
• W2082995751 hasConceptScore W2082995751C98274493 @default.
• W2082995751 hasIssue "1-2" @default.
• W2082995751 hasLocation W20829957511 @default.
• W2082995751 hasLocation W20829957512 @default.
• W2082995751 hasOpenAccess W2082995751 @default.
• W2082995751 hasPrimaryLocation W20829957511 @default.
• W2082995751 hasRelatedWork W130010948 @default.
• W2082995751 hasRelatedWork W2004312381 @default.
• W2082995751 hasRelatedWork W2009941107 @default.
• W2082995751 hasRelatedWork W2010372900 @default.
• W2082995751 hasRelatedWork W2041846912 @default.
• W2082995751 hasRelatedWork W2044628742 @default.
• W2082995751 hasRelatedWork W2089005067 @default.
• W2082995751 hasRelatedWork W2232615845 @default.
• W2082995751 hasRelatedWork W2374599087 @default.
• W2082995751 hasRelatedWork W2401495086 @default.
• W2082995751 hasVolume "37" @default.
• W2082995751 isParatext "false" @default.
• W2082995751 isRetracted "false" @default.
• W2082995751 magId "2082995751" @default.

• next